The DOI matches its Crossref record.
Anatomy and metabolism of the normal human brain studied by magnetic resonance at 1.5 Tesla.
Abstract
Proton magnetic resonance (MR) images were obtained of the human head in magnetic fields as high as 1.5 Tesla (T) using slotted resonator high radio-frequency (RF) detection coils. The images showed no RF field penetration problems and exhibited an 11 (+/- 1)-fold improvement in signal-to-noise ratio over a .12-T imaging system. The first localized phosphorus 31, carbon 13, and proton MR chemical shift spectra recorded with surface coils from the head and body in the same instrument showed relative concentrations of phosphorus metabolites, triglycerides, and, when correlated with proton images, negligible lipid (-CH2-) signal from brain tissue on the time scale of the imaging experiment. Sugar phosphate and phosphodiester concentrations were significantly elevated in the head compared with muscle. This method should allow the combined assessment of anatomy, metabolism, and biochemistry in both the normal and diseased brain.
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Cited by
Awad, I. A., Johnson, P. C., Spetzler, R. F., & Hodak, J. A. (1986) · Stroke · doi:10.1161/01.str.17.6.1090 · Cited by 572
Depth-resolved surface-coil spectroscopy (DRESS) for in Vivo 1H, 31P, and 13C NMR
Bottomley, P. A., Foster, T. B., & Darrow, R. D. (1984) · Journal of Magnetic Resonance (1969) · doi:10.1016/0022-2364(84)90179-3 · Cited by 290
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Metadata
- Authors
- Bottomley, P. A., Hart, H. R., Edelstein, W. A., Schenck, J. F., Smith, L. S., Leue, W. M., Mueller, O. M., & Redington, R. W.
- Venue
- Radiology
- Published
- 1984-02
- Volume
- 150
- Issue
- 2
- Pages
- 441-446
- ISSN
- 0033-8419 (ISSN-L)
- 1527-1315
- OpenAlex
- W2058161459
- Cited by
- 161
- References
- 0
- FWCI
- 28.02
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Anatomy and metabolism of the normal human brain studied by magnetic resonance at 1.5 Tesla. https://app.cochat.ai/papers/10.1148/radiology.150.2.6691099
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- Bottomley, P. A., Hart, H. R., Edelstein, W. A., Schenck, J. F., Smith, L. S., Leue, W. M., Mueller, O. M., & Redington, R. W. (1984). Anatomy and metabolism of the normal human brain studied by magnetic resonance at 1.5 Tesla. Radiology. https://doi.org/10.1148/radiology.150.2.6691099
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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