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Posterior pituitary gland: appearance on MR images in normal and pathologic states.
Abstract
T1-weighted magnetic resonance (MR) images of the pituitary gland and sella turcica routinely demonstrate a region of high signal intensity in the neurohypophysis. High-resolution MR imaging studies of the sella turcica in 200 subjects with a normal or abnormal sella were analyzed. The hyperintensity was found in the images of about 90% of healthy subjects and patients with microadenoma, in only 43% of patients with macroadenoma, and in 12% of patients with empty sellae. The signal was absent in several patients with functional or anatomic abnormalities of the hypothalamic-hypophyseal axis. It is concluded that the high signal intensity in the posterior lobe of the pituitary gland is present in most healthy individuals and that its absence in many patients with large intrasellar masses and empty sellae is due to compression of posterior lobe tissue. Its absence in diabetes insipidus further suggests a relationship between hyperintensity and the functional status of the hypothalamic-hypophyseal axis.
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Citations
Cited by
Lymphocytic Infundibuloneurohypophysitis as a Cause of Central Diabetes Insipidus
Imura, H., Nakao, K., Shimatsu, A., Ogawa, Y., Sando, T., Fujisawa, I., & Yamabe, H. (1993) · New England Journal of Medicine · doi:10.1056/nejm199309023291002 · Cited by 454
CENTRAL NERVOUS SYSTEM DISEASE IN LANGERHANS CELL HISTIOCYTOSIS
Grois, N. G., Favara, B. E., Mostbeck, G. H., & Prayer, D. (1998) · Hematology/Oncology Clinics of North America · doi:10.1016/s0889-8588(05)70511-6 · Cited by 347
Predictors of diabetes insipidus after transsphenoidal surgery: A review of 881 patients
Nemergut, E. C., Zuo, Z., Jane, J. A., & Laws, E. R. (2005) · Journal of neurosurgery · doi:10.3171/jns.2005.103.3.0448 · Cited by 313
Imaging of the pituitary: Recent advances
Chaudhary, V., & Bano, S. (2011) · Indian Journal of Endocrinology and Metabolism · doi:10.4103/2230-8210.84871 · Cited by 106
Neuroimaging in posttraumatic hypopituitarism
Makulski, D. D., Taber, K. H., & Chiou-Tan, F. Y. (2008) · Journal of Computer Assisted Tomography · doi:10.1097/rct.0b013e3181636ed4 · Cited by 30
Metadata
- Authors
- Colombo, N., Berry, I., Kucharczyk, J., Kucharczyk, W., de Groot, J., Larson, T., Norman, D., & Newton, T. H.
- Venue
- Radiology
- Published
- 1987-11
- Volume
- 165
- Issue
- 2
- Pages
- 481-485
- ISSN
- 0033-8419 (ISSN-L)
- 1527-1315
- OpenAlex
- W2068582330
- Cited by
- 179
- References
- 0
- FWCI
- 3.93
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Posterior pituitary gland: appearance on MR images in normal and pathologic states. https://app.cochat.ai/papers/10.1148/radiology.165.2.3659370
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- Colombo, N., Berry, I., Kucharczyk, J., Kucharczyk, W., de Groot, J., Larson, T., Norman, D., & Newton, T. H. (1987). Posterior pituitary gland: appearance on MR images in normal and pathologic states. Radiology. https://doi.org/10.1148/radiology.165.2.3659370
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
