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Cerebral astrocytomas: histopathologic correlation of MR and CT contrast enhancement with stereotactic biopsy.
Abstract
Gadolinium-labeled diethylenetriaminepentaacetic acid was used as a contrast agent for stereotactic magnetic resonance (MR) imaging in six selected patients with brain tumors who underwent stereotactic biopsy. Regions of contrast enhancement demonstrated by computed tomography (CT) and MR imaging in four of the six patients correlated with areas of malignant neovascularity and endothelial proliferation within solid tumor. Radiation necrosis produced contrast enhancement indistinguishable from that of recurrent neoplasm. Isolated tumor cells within intact white matter were identified in biopsy specimens obtained outside of regions that were depicted as abnormal by contrast material-enhanced CT, as well as by precontrast and postcontrast T1- and T2-weighted MR images.
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Cited by
Brown, T. J., Brennan, M. C., Li, M., Church, E. W., Brandmeir, N. J., Rakszawski, K. L., Patel, A. S., Rizk, E. B., Suki, D., Sawaya, R., et al. (2016) · JAMA Oncology · doi:10.1001/jamaoncol.2016.1373 · Cited by 1,081
Stummer, W., Novotny, A., Stepp, H., Goetz, C., Bise, K., & Reulen, H. J. (2000) · Journal of Neurosurgery · doi:10.3171/jns.2000.93.6.1003 · Cited by 881
Identification of noninvasive imaging surrogates for brain tumor gene-expression modules
Diehn, M., Nardini, C., Wang, D. S., McGovern, S., Jayaraman, M., Liang, Y., Aldape, K., Cha, S., & Kuo, M. D. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0801279105 · Cited by 440
Simulated Brain Tumor Growth Dynamics Using a Three-Dimensional Cellular Automaton
KANSAL, A. R., TORQUATO, S., HARSH, G. R., CHIOCCA, E. A., & DEISBOECK, T. S. (2000) · Journal of Theoretical Biology · doi:10.1006/jtbi.2000.2000 · Cited by 431
Texture Analysis: A Review of Neurologic MR Imaging Applications
Kassner, A., & Thornhill, R. E. (2010) · American Journal of Neuroradiology · doi:10.3174/ajnr.a2061 · Cited by 408
Metadata
- Authors
- Earnest, F., Kelly, P. J., Scheithauer, B. W., Kall, B. A., Cascino, T. L., Ehman, R. L., Forbes, G. S., & Axley, P. L.
- Venue
- Radiology
- Published
- 1988-03
- Volume
- 166
- Issue
- 3
- Pages
- 823-827
- ISSN
- 0033-8419 (ISSN-L)
- 1527-1315
- OpenAlex
- W1968841854
- Cited by
- 370
- References
- 0
- FWCI
- 9.07
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Cerebral astrocytomas: histopathologic correlation of MR and CT contrast enhancement with stereotactic biopsy. https://app.cochat.ai/papers/10.1148/radiology.166.3.2829270
- The paper
- Earnest, F., Kelly, P. J., Scheithauer, B. W., Kall, B. A., Cascino, T. L., Ehman, R. L., Forbes, G. S., & Axley, P. L. (1988). Cerebral astrocytomas: histopathologic correlation of MR and CT contrast enhancement with stereotactic biopsy. Radiology. https://doi.org/10.1148/radiology.166.3.2829270
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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