Cited by 130Cardiovascular Function and Risk FactorsCardiac Imaging and DiagnosticsAdvanced MRI Techniques and Applications

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Evaluation of left ventricular diastolic function with cardiac MR imaging.

Caudron, Jérôme, Fares, Jeannette, Bauer, Fabrice, Dacher, Jean-Nicolas·2011·Radiographics

DOI 10.1148/rg.311105049

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Abstract

Assessment of left ventricular (LV) function with cardiac magnetic resonance (MR) imaging is often limited to evaluation of systolic function, including analysis of regional wall motion, measurement of mass and volume, and estimation of ejection fraction. However, diastolic dysfunction is present in various heart diseases, particularly in heart failure with preserved ejection fraction, which is increasingly prevalent and is associated with a poor prognosis. In daily practice, the assessment of diastolic function is mainly performed with transthoracic echocardiography. Evaluation of diastolic function with cardiac MR imaging is seldom performed in clinical practice. However, basic assessment of LV relaxation and stiffness abnormalities can be achieved with MR imaging by using a combination of left atrium size measurement and phase-contrast evaluation of transmitral flow. In addition, assessment of pulmonary venous flow and the LV filling curve can also be performed. Furthermore, MR imaging with late gadolinium enhancement sequences provides insight into the extent of myocardial fibrosis, which strongly influences LV stiffness. Finally, phase-contrast evaluation of tissue velocities, myocardial tagging, MR spectroscopy, and MR elastography are promising tools for a better understanding of LV diastolic function but require further evaluation.

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Authors: Caudron, J., Fares, J., Bauer, F., & Dacher, J.-N.
Affiliations: Centre Hospitalier Universitaire de Rouen (FR)
ORCID: Bauer, Fabrice
Dacher, Jean-Nicolas
Venue: Radiographics
Publisher: Radiological Society of North America (RSNA)
Published: 2011-01
Volume: 31
Issue: 1
Pages: 239-259
ISSN: 0271-5333 (ISSN-L)
1527-1323
DOI: 10.1148/rg.311105049
OpenAlex: W2096980073
Cited by: 129
References: 53
Citations by year: 2026: 3 · 2025: 4 · 2024: 7 · 2023: 8 · 2022: 7 · 2021: 12 · 2020: 11 · 2019: 7 · 2018: 5 · 2017: 8 · 2016: 7 · 2015: 6 · 2014: 15 · 2013: 10 · 2012: 12
FWCI: 2.27
Type: journal article
Language: en
Open access: closed
Locations: Radiographics (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Function and Risk Factors
Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Cardiac Imaging and Diagnostics
Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Advanced MRI Techniques and Applications
Keywords: left ventricular diastolic function, diastolic dysfunction, heart failure with preserved ejection fraction, left ventricular relaxation, left ventricular stiffness, left atrium size, transmitral flow, pulmonary venous flow, late gadolinium enhancement, myocardial fibrosis, phase-contrast MRI, myocardial tagging, MR spectroscopy, magnetic resonance elastography, tissue velocity imaging
MeSH terms: Blood Flow Velocity, Diastole, Heart Failure, Humans, Magnetic Resonance Imaging, Cardiomyopathies, Myocardial Infarction, Pulmonary Circulation, Pulmonary Veins, Ventricular Dysfunction, Left

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Evaluation of left ventricular diastolic function with cardiac MR imaging.

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