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Performance of an Open-Source Large Language Model in Extracting Information from Free-Text Radiology Reports
Open accessAbstract
“Just Accepted” papers have undergone full peer review and have been accepted for publication in Radiology: Artificial Intelligence. This article will undergo copyediting, layout, and proof review before it is published in its final version. Please note that during production of the final copyedited article, errors may be discovered which could affect the content. Purpose To assess the performance of a local open-source large language model (LLM) on various information extraction tasks from real-life emergency brain MRI reports. Materials and Methods All consecutive emergency brain MRI reports written in 2022 from a French quaternary center were retrospectively reviewed. Two radiologists identified MRIs that were performed for headaches. Four radiologists scored reports' conclusions as normal or abnormal. Abnormalities were labeled as either headache-causing or incidental. Vicuna, an open-source LLM, performed the same tasks. Vicuna’s performance metrics were evaluated using the radiologists’ consensus as the reference standard. Results Among the 2398 reports during the study period, radiologists identified 595 that included headaches in their indication (median age of patients, 35 years [IQR, 26–51], 68% (403/595) female). A positive finding was reported in 227/595 (38%) cases, 136 of which could explain the headache. The LLM had a sensitivity/specificity (95%CI), respectively, of 98% (583/595)(97–99)/99% (1791/1803)(99–100) for detecting the presence of headache in the clinical context, 99% (514/517)(98–100)/99% (68/69)(92–100) for the use of contrast medium injection, 97% (219/227)(93–99)/99% (364/368)(97–100) for study categorization as normal or abnormal and 88% (120/136)(82– 93)/73% (66/91)(62–81) for causal inference between MRI findings and headache. Conclusion An open-source LLM was able to extract information from free-text radiology reports with excellent accuracy without requiring further training. ©RSNA, 2024
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“Most studies applying LLM on clinical notes have been conducted in the US without individual consent, using de-identified data, with only one study from France utilising retrospective MRI reports without identifiable data [5, 6, 13, 14, 17–20].”
From A pilot feasibility study comparing large language models in extracting key information from ICU patient text records from an Irish population (2024) · cites this paper as [20]
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Large language models encode clinical knowledge
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Large Language Models Encode Clinical Knowledge
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Metadata
- Authors
- Le Guellec, B., Lefèvre, A., Geay, C., Shorten, L., Bruge, C., Hacein-Bey, L., Amouyel, P., Pruvo, J.-P., Kuchcinski, G., & Hamroun, A.
- Affiliations
- Inserm (FR)
- ORCID
- Venue
- Radiology: Artificial Intelligence
- Published
- 2024-07-01
- Volume
- 6
- Issue
- 4
- Pages
- e230364-e230364
- ISSN
- 2638-6100 (ISSN-L)
- PMC
- PMC11294959
- OpenAlex
- W4396722287
- Cited by
- 115
- References
- 28
- Citations by year
- 2026: 42 · 2025: 60 · 2024: 12
- FWCI
- 10.66
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Licence
- cc-by
- Locations
- Radiology Artificial Intelligence (publishedVersion)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- HAL (submittedVersion, cc-by)
- eScholarship (California Digital Library) (submittedVersion, cc-by)
- LillOA (Université de Lille (University Of Lille)) (submittedVersion)
- LillOA (Université de Lille (University Of Lille)) (submittedVersion, other-oa)
- Topics
- Health Sciences › Medicine › Health Informatics › Artificial Intelligence in Healthcare and Education
- Physical Sciences › Computer Science › Artificial Intelligence › Topic Modeling
- Physical Sciences › Computer Science › Artificial Intelligence › Machine Learning in Healthcare
- Keywords
- open-source large language models, vicuña, headache, contrast medium injection, incidental finding, radiologist consensus, local LLM deployment, radiology education, radiology workforce shortage
- MeSH terms
- Adult, Brain, Emergency Service, Hospital, Female, Headache, Humans, Magnetic Resonance Imaging, Male, Middle Aged, Natural Language Processing, Retrospective Studies, Sensitivity and Specificity
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