Antibodies to tumor necrosis factor-alpha inhibit liver regeneration after partial hepatectomy

Single dose intravenous thioacetamide administration as a model of acute liver damage in rats

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Evidence for non-traditional activation of complement factor C3 during murine liver regeneration

Clark, A., Weymann, A., Hartman, E., Turmelle, Y. P., Carroll, M. C., Thurman, J. M., Holers, V. M., Hourcade, D. E., & Rudnick, D. A. (2008) · Molecular Immunology · doi:10.1016/j.molimm.2008.03.008 · Cited by 87

Cytokine-Responsive Gene-2/IFN-Inducible Protein-10 Expression in Multiple Models of Liver and Bile Duct Injury Suggests a Role in Tissue Regeneration

Koniaris, L. G., Zimmers, T. A., Hsiao, E. C., Chavin, K. D., Sitzmann, J. V., & Farber, J. M. (2001) · The Journal of Immunology · doi:10.4049/jimmunol.167.1.399 · Cited by 84

The platelet receptor CLEC-2 blocks neutrophil mediated hepatic recovery in acetaminophen induced acute liver failure

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Regulation of Hepatocyte Cell Cycle Progression and Differentiation by Type I Collagen Structure

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Antioxidants attenuate nuclear factor-kappa B activation and tumor necrosis factor-alpha production in alcoholic hepatitis patient monocytes and rat Kupffer cells, in vitro

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Tumour necrosis factor alpha (TNF alpha) suppresses apoptosis and induces DNA synthesis in rodent hepatocytes: a mediator of the hepatocarcinogenicity of peroxisome proliferators?

Rolfe, M. (1997) · Carcinogenesis · doi:10.1093/carcin/18.11.2277 · Cited by 82

Mouse CD11b+Kupffer Cells Recruited from Bone Marrow Accelerate Liver Regeneration after Partial Hepatectomy

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Hepatic NKT cells: friend or foe?

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Single-cell omics analysis reveals functional diversification of hepatocytes during liver regeneration

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TIGIT safeguards liver regeneration through regulating natural killer cell-hepatocyte crosstalk

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NO sensitizes rat hepatocytes to proliferation by modifying S-adenosylmethionine levels

García–Trevijano, E. R., Martínez‐Chantar, M. L., Latasa, M. U., Mato, J. M., & Avila, M. A. (2002) · Gastroenterology · doi:10.1053/gast.2002.33020 · Cited by 78

Cytokine Expression in Hepatocytes: Role of Oxidant Stress

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Liver Regeneration and the Atrophy-Hypertrophy Complex

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Advances in the regulation of liver regeneration

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Contribution of the Lymphotoxin β Receptor to Liver Regeneration

Anders, R. A., Subudhi, S. K., Wang, J. H., Pfeffer, K., & Fu, Y. (2005) · The Journal of Immunology · doi:10.4049/jimmunol.175.2.1295 · Cited by 73

TNF-α Regulates Transforming Growth Factor-α Expression in Regenerating Murine Liver and Isolated Hepatocytes

Gallucci, R. M., Simeonova, P. P., Toriumi, W., & Luster, M. I. (2000) · The Journal of Immunology · doi:10.4049/jimmunol.164.2.872 · Cited by 73

Effects of chronic ethanol consumption on cytokine regulation of liver regeneration

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Circulating interleukin-1 and tumor necrosis factor antagonists in liver disease

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Induction Of Mdr1b Expression by Tumor Necrosis Factor–α in Rat Liver Cells Is Independent of P53 But Requires Nf–κB Signaling

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Impact of bacteria on the phenotype, functions, and therapeutic activities of invariant NKT cells in mice

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Mechanisms and biomarkers of liver regeneration after drug-induced liver injury

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Platelets Promote Liver Regeneration under Conditions of Kupffer Cell Depletion after Hepatectomy in Mice

Murata, S., Matsuo, R., Ikeda, O., Myronovych, A., Watanabe, M., Hisakura, K., Nakano, Y., Hashimoto, I., & Ohkohchi, N. (2008) · World Journal of Surgery · doi:10.1007/s00268-008-9493-0 · Cited by 66

Therapeutic opportunities for alcoholic steatohepatitis and nonalcoholic steatohepatitis: exploiting similarities and differences in pathogenesis

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Role of nitric oxide in liver regeneration

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Normal Liver Regeneration in P50/Nuclear Factor κB1 Knockout Mice

DeAngelis, R. A., Kovalovich, K. K., Cressman, D. E., & Taub, R. A. (2001) · Hepatology · doi:10.1053/jhep.2001.23192 · Cited by 66

Ethanol Induces Redox‐Sensitive Cell‐Cycle Inhibitors and Inhibits Liver Regeneration After Partial Hepatectomy

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High mobility group B1 impairs hepatocyte regeneration in acetaminophen hepatotoxicity

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Role of Kupffer cells and oxidants in signaling peroxisome proliferator-induced hepatocyte proliferation

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Suppression of mouse hepatocyte apoptosis by peroxisome proliferators: role of PPARα and TNFα

Hasmall, S. C., James, N. H., Macdonald, N., Gonzalez, F. J., Peters, J. M., & Roberts, R. A. (2000) · Mutation research. Fundamental and molecular mechanisms of mutagenesis · doi:10.1016/s0027-5107(99)00236-5 · Cited by 62

Novel Role of Oxidants in the Molecular Mechanism of Action of Peroxisome Proliferators

Rusyn, I., Rose, M., Bojes, H. K., & Thurman, R. G. (2000) · Antioxidants and Redox Signaling · doi:10.1089/15230860050192350 · Cited by 61

Novel functions of platelets in the liver

Kurokawa, T., Zheng, Y., & Ohkohchi, N. (2015) · Journal of Gastroenterology and Hepatology · doi:10.1111/jgh.13244 · Cited by 60

Hepatocyte organoids and cell transplantation: What the future holds

Peng, W. C., Kraaier, L. J., & Kluiver, T. A. (2021) · Experimental & Molecular Medicine · doi:10.1038/s12276-021-00579-x · Cited by 62

Sex difference in the proliferative response of mouse hepatocytes to treatment with the CAR ligand, TCPOBOP

Columbano, A. (2003) · Carcinogenesis · doi:10.1093/carcin/bgg063 · Cited by 62

Genomic Profiling in Nuclear Receptor-Mediated Toxicity

Woods, C. G., Heuvel, J. P. V., & Rusyn, I. (2007) · Toxicologic Pathology · doi:10.1080/01926230701311351 · Cited by 60

The hippo pathway: A master regulator of liver metabolism, regeneration, and disease

Nguyen‐Lefebvre, A. T., Selzner, N., Wrana, J. L., & Bhat, M. (2021) · The FASEB Journal · doi:10.1096/fj.202002284rr · Cited by 58

Cytokines in non-genotoxic hepatocarcinogenesis

Roberts, R. A. (1999) · Carcinogenesis · doi:10.1093/carcin/20.8.1397 · Cited by 58

Impaired Ras membrane association and activation in PPARα knockout mice after partial hepatectomy

Wheeler, M. D., Smutney, O. M., Check, J. F., Rusyn, I., Schulte‐Hermann, R., & Thurman, R. G. (2003) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.00175.2002 · Cited by 57

Glutathione modulates rat and mouse hepatocyte sensitivity to tumor necrosis factor α toxicity

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Liver regeneration

Diehl, A. M. (2002) · Frontiers in bioscience · doi:10.2741/a925 · Cited by 55

Liver Regeneration after Liver Transplantation

Taki‐Eldin, A., Zhou, L., Xie, H., & Zheng, S. (2012) · European Surgical Research · doi:10.1159/000337865 · Cited by 55

NF-κB activation in Kupffer cells after partial hepatectomy

Yang, L., Magness, S. T., Bataller, R. A., Rippe, R. A., & Brenner, D. A. (2005) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.00526.2004 · Cited by 55

Activation of Mouse Natural Killer T Cells Accelerates Liver Regeneration After Partial Hepatectomy

Nakashima, H., Inui, T., Habu, Y., Kinoshita, M., Nagao, S., Kawaguchi, A., Miura, S., Shinomiya, N., Yagita∥, H., & Seki, S. (2006) · Gastroenterology · doi:10.1053/j.gastro.2006.08.028 · Cited by 55

Macrophages and platelets in liver fibrosis and hepatocellular carcinoma

Casari, M., Siegl, D., Deppermann, C., & Schuppan, D. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1277808 · Cited by 55

Liver regeneration: a spotlight on the novel role of platelets and serotonin

Clavien, P. (2008) · Swiss Medical Weekly · doi:10.4414/smw.2008.12231 · Cited by 52

Pioglitazone promotes survival and prevents hepatic regeneration failure after partial hepatectomy in obese and diabetic KK-Ay mice #

Aoyama, T., Ikejima, K., Kon, K., Okumura, K., Arai, K., & Watanabe, S. (2009) · Hepatology · doi:10.1002/hep.22828 · Cited by 53

Diabetes Mellitus and Liver Surgery: The Effect of Diabetes on Oxidative Stress and Inflammation

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Upregulation of lymphotoxin β expression in liver progenitor (oval) cells in chronic hepatitis C

Lowes, K. N., Croager, E. J., Abraham, L. J., Olynyk, J. K., & Yeoh, G. C. (2003) · Gut · doi:10.1136/gut.52.9.1327 · Cited by 52

Aspartate alleviates liver injury and regulates mRNA expressions of TLR4 and NOD signaling-related genes in weaned pigs after lipopolysaccharide challenge

Leng, W., Liu, Y., Shi, H., Li, S., Zhu, H., Pi, D., Hou, Y., & Gong, J. (2014) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2014.01.010 · Cited by 50

TNF/LT? double knockout mice display abnormal inflammatory and regenerative responses to acute and chronic liver injury

Knight, B., & Yeoh, G. C. (2004) · Cell and Tissue Research · doi:10.1007/s00441-004-1003-6 · Cited by 50

After Portal Branch Ligation in Rat, Nuclear Factor κB, Interleukin–6, Signal Transducers and Activators of Transcription 3, C– Fos , C– Myc , and C– Jun Are Similarly Induced in the Ligated and Nonligated Lobes

Stärkel, P., Horsmans, Y., Sempoux, C. L., Saeger, C. D., Wary, J., Lause, P., Maiter, D. M., & Lambotte, L. (1999) · Hepatology · doi:10.1002/hep.510290503 · Cited by 49

Delayed fas-mediated hepatocyte apoptosis during liver regeneration in mice: hepatoprotective role of TNFα

Takehara, T., Hayashi, N., Mita, E., Kanto, T., Tatsumi, T., Sasaki, Y., Kasahara, A., & Hori, M. (1998) · Hepatology · doi:10.1002/hep.510270625 · Cited by 50

Rosiglitazone inhibits mouse liver regeneration

Turmelle, Y. P., Shikapwashya, O., Tu, S., Hruz, P. W., Yan, Q., & Rudnick, D. A. (2006) · The FASEB Journal · doi:10.1096/fj.06-6511fje · Cited by 49

Tumor necrosis factor-alpha modulates CCAAT/enhancer binding proteins-DNA binding activities and promotes hepatocyte-specific gene expression during liver regeneration

Diehl, A. M., Yang, S. Q., Yin, M., Lin, H. Z., Nelson, S., & Bagby, G. J. (1995) · Hepatology · doi:10.1002/hep.1840220136 · Cited by 49

ROLE OF KUPFFER CELLS IN PEROXISOME PROLIFERATOR-INDUCED HEPATOCYTE PROLIFERATION*

Rose, M., Rusyn, I., Bojes, H. K., Germolec, D. R., Luster, M. I., & Thurman, R. G. (1999) · Drug Metabolism Reviews · doi:10.1081/dmr-100101909 · Cited by 47

Effect of silibinin and vitamin E on restoration of cellular immune response after partial hepatectomy

Horváth, M. É., Gonzalez-Cabello, R., Blázovics, A., van der Looij, M., Barta, I., Műzes, G., Gergely, P., & Fehér, J. (2001) · Journal of Ethnopharmacology · doi:10.1016/s0378-8741(01)00298-7 · Cited by 46

Liver regeneration: Prospects for therapy based on new technologies

Kay, M. A., & Fausto, N. (1997) · Molecular Medicine Today · doi:10.1016/s1357-4310(96)10062-9 · Cited by 46

Loss of cyclin D1 does not inhibit the proliferative response of mouse liver to mitogenic stimuli

Ledda-Columbano, G. M., Pibiri, M., Concas, D., Cossu, C., Tripodi, M., & Columbano, A. (2002) · Hepatology · doi:10.1053/jhep.2002.36159 · Cited by 45

V. Knocking out genes to study liver regeneration: present and future

Fausto, N. (1999) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.1999.277.5.g917 · Cited by 44

Protection of Reduced-Size Liver for Transplantation

Franco-Gou, R., Peralta, C., Massip‐Salcedo, M., Xaus, C., Serafín, A., & Roselló‐Catafau, J. (2004) · American Journal of Transplantation · doi:10.1111/j.1600-6143.2004.00532.x · Cited by 44

Clinical Implications of Advances in the Basic Science of Liver Repair and Regeneration

Karp, S. J. (2009) · American Journal of Transplantation · doi:10.1111/j.1600-6143.2009.02731.x · Cited by 43

MicroRNAs in Liver Regeneration

Chen, X., Zhao, Y., Wang, F., Bei, Y., Xiao, J., & Yang, C. (2015) · Cellular Physiology and Biochemistry · doi:10.1159/000430381 · Cited by 44

HMG Box Transcriptional Repressor HBP1 Maintains a Proliferation Barrier in Differentiated Liver Tissue

Shih, H. H., Xiu, M., Berasi, S. P., Sampson, E. M., Leiter, A. B., Paulson, K. E., & Yee, A. S. (2001) · Molecular and Cellular Biology · doi:10.1128/mcb.21.17.5723-5732.2001 · Cited by 44

Novel Approaches to Preventing Ischemia-Reperfusion Injury During Liver Transplantation

Akhtar, M. Z., Henderson, T., Sutherland, A., Vogel, T., & Friend, P. J. (2013) · Transplantation Proceedings · doi:10.1016/j.transproceed.2013.04.004 · Cited by 43

Effects of Ischemic Preconditioning on Regenerative Capacity of Hepatocyte in the Ischemically Damaged Rat Livers

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Some lessons from the tissue transglutaminase knockout mouse

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Molecular and cellular features of hepatic regeneration

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Hepatoprotection by Ginsenoside Rg1 in alcoholic liver disease

Yang, C. N., He, X., Zhao, J., & Huang, W. (2021) · International Immunopharmacology · doi:10.1016/j.intimp.2020.107327 · Cited by 41

Lead stimulates intercellular signalling between hepatocytes and Kupffer cells

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Triiodothyronine stimulates hepatocyte proliferation in two models of impaired liver regeneration

Columbano, A., Simbula, M., Pibiri, M., Perra, A., Deidda, M., Locker, J. D., Pisanu, A., Uccheddu, A., & Ledda‐Columbano, G. M. (2008) · Cell Proliferation · doi:10.1111/j.1365-2184.2008.00532.x · Cited by 39

Signal Transduction of Platelet-Induced Liver Regeneration and Decrease of Liver Fibrosis

Murata, S., Maruyama, T., Nowatari, T., Takahashi, K., & Ohkohchi, N. (2014) · International Journal of Molecular Sciences · doi:10.3390/ijms15045412 · Cited by 39

Effect of ethanol on tumor necrosis factor signaling during liver regeneration

Diehl, A. M. (1999) · Clinical Biochemistry · doi:10.1016/s0009-9120(99)00057-0 · Cited by 40

p53-independent induction of p21WAF1/CIP1 expression in pericentral hepatocytes following carbon tetrachloride intoxication.

Serfas, M. S., Goufman, E., Feuerman, M. H., Gartel, A. L., & Tyner, A. L. (1997) · PubMed · Cited by 39

Role of macrophages in regeneration of liver

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TNF-α and IL-6 signals from the bone marrow derived cells are necessary for normal murine liver regeneration

Sudo, K., Yamada, Y., Saito, K., Shimizu, S., Ohashi, H., Kato, T., Moriwaki, H., Ito, H., & Seishima, M. (2008) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2008.09.010 · Cited by 38

Post-exposure targeting of specific epitopes on ricin toxin abrogates toxin-induced hypoglycemia, hepatic injury, and lethality in a mouse model

Roche, J. K., Stone, M. K., Gross, L. K., Lindner, M. H., Seaner, R. M., Pincus, S. H., & Obrig, T. G. (2008) · Laboratory Investigation · doi:10.1038/labinvest.2008.83 · Cited by 38

Alcoholic Hepatitis: Prognostic Models and Treatment

Singal, A. K., & Shah, V. H. (2011) · Gastroenterology Clinics of North America · doi:10.1016/j.gtc.2011.06.008 · Cited by 37

Tumor necrosis factor alpha is not required for WY14,643-induced cell proliferation

Lawrence, J. W. (2001) · Carcinogenesis · doi:10.1093/carcin/22.3.381 · Cited by 37

Nonalcoholic Fatty Liver Disease: Implications for Alcoholic Liver Disease Pathogenesis

Diehl, A. M. (2001) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.2001.tb02368.x · Cited by 37

IL6 supports long-term expansion of hepatocytes in vitro

Guo, R., Jiang, M., Wang, G., Li, B., Jia, X., Ai, Y., Chen, S., Tang, P., Liu, A., Yuan, Q., et al. (2022) · Nature Communications · doi:10.1038/s41467-022-35167-8 · Cited by 36

Lipopolysaccharide potentiates the effect of hepatocyte growth factor on hepatocyte replication in rats by augmenting AP-1 activity

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Endogenous glucocorticoids released during acute toxic liver injury enhance hepatic IL-10 synthesis and release

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Hepatocyte proliferation induced in rats by lead nitrate is suppressed by several tumor necrosis factor α inhibitors

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Dexamethasone inhibits induction of liver tumor necrosis factor-alpha mRNA and liver growth induced by lead nitrate and ethylene dibromide.

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Novel therapy for liver regeneration by increasing the number of platelets

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The CAR Nuclear Receptor and Hepatocyte Proliferation * #

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Control of rate and extent of the proliferative response after partial hepatectomy

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Cytokines and the Molecular Mechanisms of Alcoholic Liver Disease

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Post-hepatectomy liver regeneration in the context of bile acid homeostasis and the gut-liver signaling axis

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Acute Hepatotoxicant Exposure Induces TNFR-Mediated Hepatic Injury and Cytokine/Apoptotic Gene Expression

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Antitumour necrosis factor-α agents and development of new-onset cirrhosis or non-alcoholic fatty liver disease: a retrospective cohort

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Effect of partial liver resection on tumour growth

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HEPATIC REGENERATION INDUCES TRANSIENT ACUTE PHASE REACTION: SYSTEMIC ELEVATION OF ACUTE PHASE REACTANTS AND SOLUBLE CYTOKINE RECEPTORS

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Keratinocyte growth factor induces proliferation of hepatocytes and epithelial cells throughout the rat gastrointestinal tract Housley RM, Morris CF, Boyle W, Ring B, Biltz R, Tarpley JE, Aukerman SL, et al. J Clin Invest 1994; 94: 1764?1777

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Opposing roles of RAGE and Myd88 signaling in extensive liver resection

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