Antioxidant mechanism of heme oxygenase-1 involves an increase in superoxide dismutase and catalase in experimental diabetes

Role of Oxidative Stress in Development of Complications in Diabetes

Baynes, J. (1991) · Diabetes · doi:10.2337/diab.40.4.405 · Cited by 3,791

Angiotensin II-mediated hypertension in the rat increases vascular superoxide production via membrane NADH/NADPH oxidase activation. Contribution to alterations of vasomotor tone.

Rajagopalan, S., Kurz, S. D., Münzel, T. F., Tarpey, M. M., Freeman, B. Α., Griendling, K. K., & Harrison, D. G. (1996) · Journal of Clinical Investigation · doi:10.1172/jci118623 · Cited by 2,467

Number and Migratory Activity of Circulating Endothelial Progenitor Cells Inversely Correlate With Risk Factors for Coronary Artery Disease

Vasa‐Nicotera, M., Fichtlscherer, S., Aicher, A., Adler, K., Urbich, C., Martin, H., Zeiher, A. M., & Dimmeler, S. (2001) · Circulation Research · doi:10.1161/hh1301.093953 · Cited by 2,328

Ferritin: a cytoprotective antioxidant strategem of endothelium.

Balla, G., Jacob, H., Balla, J., Rosenberg, M. E., Nath, K. A., Apple, F., Eaton, J. W., & Vercellotti, G. M. (1992) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)37165-0 · Cited by 1,097

Smooth muscle cell-derived carbon monoxide is a regulator of vascular cGMP.

Morita, T., Perrella, M. A., Lee, M. E., & Kourembanas, S. (1995) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.92.5.1475 · Cited by 712

Vascular protection: superoxide dismutase isoforms in the vessel wall.

Faraci, F., & Didion, S. (2004) · Arteriosclerosis, Thrombosis and Vascular Biology · doi:10.1161/01.atv.0000133604.20182.cf · Cited by 528

Carbon monoxide suppresses arteriosclerotic lesions associated with chronic graft rejection and with balloon injury

Otterbein, L. E., Zuckerbraun, B. S., Haga, M., Liu, F., Song, R., Usheva, A., Stachulak, C., Bodyak, N. D., Smith, R. N., Csizmadia, E., et al. (2003) · Nature Medicine · doi:10.1038/nm817 · Cited by 527

Oxidation of Tetrahydrobiopterin by Peroxynitrite: Implications for Vascular Endothelial Function

Milstien, S., & Katušić, Z. S. (1999) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.1999.1422 · Cited by 492

Exogenous administration of heme oxygenase-1 by gene transfer provides protection against hyperoxia-induced lung injury

Otterbein, L. E., Kolls, J. K., Mantell, L. L., Cook, J. L., Alam, J., & Choi, A. M. K. (1999) · Journal of Clinical Investigation · doi:10.1172/jci5342 · Cited by 492

Inhibition of platelet aggregation by carbon monoxide is mediated by activation of guanylate cyclase.

Brüne, B., & Ullrich, V. (1987) · Molecular Pharmacology · doi:10.1016/s0026-895x(25)13029-0 · Cited by 472

3D collagen architecture regulates cell adhesion through degradability, thereby controlling metabolic and oxidative stress

Velez, D. O., Ranamukhaarachchi, S. K., Kumar, A., Modi, R. N., Lim, E. W., Engler, A. J., Metallo, C. M., & Fraley, S. I. (2019) · Integrative Biology · doi:10.1093/intbio/zyz019 · Cited by 45

Upregulation of Nrf2 signaling and suppression of ferroptosis and NF-κB pathway by leonurine attenuate iron overload-induced hepatotoxicity

Salama, S. A., Abdel‐Bakky, M. S., & Mohamed, A. A. (2022) · Chemico-Biological Interactions · doi:10.1016/j.cbi.2022.109875 · Cited by 45

Oxidant-Redox Regulation of Pulmonary Vascular Responses to Hypoxia and Nitric Oxide-cGMP Signaling

Wolin, M. S., Gupte, S. A., Neo, B. H., Gao, Q., & Ahmad, M. (2010) · Cardiology in Review · doi:10.1097/crd.0b013e3181c9f088 · Cited by 47

The role of pericytes in brain disorders: from the periphery to the brain

Hirunpattarasilp, C., Attwell, D., & Freitas, F. (2019) · Journal of Neurochemistry · doi:10.1111/jnc.14725 · Cited by 44

An analysis of the DOCA-salt model of hypertension in HO-1−/− mice and the Gunn rat

Nath, K. A., d’Uscio, L. V., Juncos, J. P., Croatt, A. J., Manriquez, M. C., Pittock, S. T., & Katušić, Z. S. (2007) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00870.2006 · Cited by 44

Impact of silencing HO‐2 on EC‐SOD and the mitochondrial signaling pathway

Türkseven, S., Drummond, G., Rezzani, R., Rodella, L. F., Quan, S., Ikehara, S., & Abraham, N. G. (2006) · Journal of Cellular Biochemistry · doi:10.1002/jcb.21138 · Cited by 43

Antioxidant and Cytoprotective Effects of (−)-Epigallocatechin-3-(3″-O-methyl) Gallate

Kim, E., Han, S. Y., Hwang, K., Kim, D., Kim, E., Hossain, M. A., Kim, J., & Cho, J. Y. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20163993 · Cited by 43

Emerging links between non‐neurogenic lower urinary tract symptoms secondary to benign prostatic obstruction, metabolic syndrome and its components: A systematic review

Russo, G. I., Castelli, T., Urzì, D., Privitera, S., Vignera, S. L., Condorelli, R. A., Calogero, A. E., Favilla, V., Cimino, S., & Morgia, G. (2015) · International Journal of Urology · doi:10.1111/iju.12877 · Cited by 42

Upregulating the Heme Oxygenase System Suppresses Left Ventricular Hypertrophy in Adult Spontaneously Hypertensive Rats for 3 Months

Ndisang, J. F., & Jadhav, A. (2009) · Journal of Cardiac Failure · doi:10.1016/j.cardfail.2009.02.003 · Cited by 42

Chronic CO levels has a beneficial effect on vascular relaxation in diabetes

Pascoli, M. D., Rodella, L. F., Sacerdoti, D., Bolognesi, M., Türkseven, S., & Abraham, N. G. (2005) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2005.12.082 · Cited by 42

Epoxyeicosatrienoic acids and heme oxygenase-1 interaction attenuates diabetes and metabolic syndrome complications

Burgess, A., Vanella, L., Bellner, L., Schwartzman, M. L., & Abraham, N. G. (2011) · Prostaglandins & Other Lipid Mediators · doi:10.1016/j.prostaglandins.2011.10.002 · Cited by 41

Cobalt-Protoporphyrin Improves Heart Function by Blunting Oxidative Stress and Restoring NO Synthase Equilibrium in an Animal Model of Experimental Diabetes

Cao, J. J., Vecoli, C., Neglia, D., Tavazzi, B., Lazzarino, G., Novelli, M., Masiello, P., Wang, Y., Puri, N., Paolocci, N., et al. (2012) · Frontiers in Physiology · doi:10.3389/fphys.2012.00160 · Cited by 41

Correlation Between Lipid Profile and Heme Oxygenase System in Patients With Benign Prostatic Hyperplasia

Vanella, L., Russo, G. I., Cimino, S., Fragalà, E., Favilla, V., Volti, G. L., Barbagallo, I. A., Sorrenti, V., & Morgia, G. (2014) · Urology · doi:10.1016/j.urology.2014.03.007 · Cited by 40

The hepatoprotective effect of sitagliptin against hepatic ischemia reperfusion-induced injury in rats involves Nrf-2/HO-1 pathway

Abdel-Gaber, S. A., Geddawy, A., & Moussa, R. A. (2019) · Pharmacological Reports · doi:10.1016/j.pharep.2019.06.006 · Cited by 40

IL-8 as a Potential Therapeutic Target for Periodontitis and Its Inhibition by Caffeic Acid Phenethyl Ester In Vitro

Huang, Y., Tseng, K.-F., Tsai, P.-H., Wang, J.-S., Lee, C.-Y., & Shen, M. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22073641 · Cited by 40

Heme Oxygenase-Derived Carbon Monoxide Restores Vascular Function in Type 1 Diabetes

Rodella, L. F., Vanella, L., Peterson, S. J., Drummond, G., Rezzani, R., Falck, J. R., & Abraham, N. G. (2008) · Drug Metabolism Letters · doi:10.2174/187231208786734058 · Cited by 41

Induction of heme oxygenase-1 with β-CD-hemin complex mitigates cadmium-induced oxidative damage in the roots of Medicago sativa

Fu, G.-Q., Zhang, L., Cui, W., Wang, Y., Shen, W., Ren, Y., & Zheng, T. (2011) · Plant and Soil · doi:10.1007/s11104-011-0779-x · Cited by 40

Insulin Up-Regulates Heme Oxygenase-1 Expression in 3T3-L1 Adipocytes via PI3-Kinase- and PKC-Dependent Pathways and Heme Oxygenase-1–Associated MicroRNA Downregulation

Chang, C.-L., Au, L., Huang, S., Kwok, C., Ho, L., & Juan, C. (2010) · Endocrinology · doi:10.1210/en.2010-0493 · Cited by 40

Potential Benefits of Berry Anthocyanins on Vascular Function

Festa, J., Boit, M. D., Hussain, A., & Singh, H. (2021) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.202100170 · Cited by 40

Role of Heme Oxygenase-1 in Polymyxin B-Induced Nephrotoxicity in Rats

da Fonseca, C. D., Watanabe, M., & Vattimo, M. D. F. F. (2012) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.00925-12 · Cited by 39

Modulation by heme and zinc protoporphyrin of colonic heme oxygenase-1 and experimental inflammatory bowel disease in the rat

Varga, C., László, F. A., Fritz, P., Cavicchi, M., Lamarque, D., Horvath, K., Pósa, A., Berkó, A. M., & Whittle, B. J. R. (2007) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2006.12.022 · Cited by 38

A Phosphodiesterase III Inhibitor Protects Rat Liver From Sinusoidal Obstruction Syndrome Through Heme Oxygenase-1 Induction

Narita, M., Hatano, E., Ikai, I., Miyagawa‐Hayashino, A., Yanagida, A., Nagata, H., Asechi, H., Taura, K., & Üemoto, S. (2009) · Annals of Surgery · doi:10.1097/sla.0b013e3181a38ed5 · Cited by 37

Improved myocardial perfusion in chronic diabetic mice by the up‐regulation of pLKB1 and AMPK signaling

Kusmic, C., L’Abbate, A., Sambuceti, G., Drummond, G., Barsanti, C., Matteucci, M., Cao, J. J., Piccolomini, F., Cheng, J., & Abraham, N. G. (2010) · Journal of Cellular Biochemistry · doi:10.1002/jcb.22486 · Cited by 38

Transplantation of Bone Marrow Mesenchymal Stem Cells Prevents Radiation‐Induced Artery Injury by Suppressing Oxidative Stress and Inflammation

Shen, Y., Jiang, X. M., Meng, L., Xia, C., Zhang, L., & Xin, Y. (2018) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2018/5942916 · Cited by 36

Impairment of Dilator Responses of Cerebral Arterioles During Diabetes Mellitus

Kitayama, J., Faraci, F. M., Gunnett, C. A., & Heistad, D. D. (2006) · Stroke · doi:10.1161/01.str.0000231654.79017.df · Cited by 36

Telmisartan attenuates N-nitrosodiethylamine-induced hepatocellular carcinoma in mice by modulating the NF-κB-TAK1-ERK1/2 axis in the context of PPARγ agonistic activity

Saber, S., Khodir, A. E., Soliman, W. E., Salama, M. M., Abdo, W. S., El-Saeed, B., Nader, K., Abdelnasser, A., Megahed, N., Basuony, M., et al. (2019) · Naunyn-Schmiedeberg s Archives of Pharmacology · doi:10.1007/s00210-019-01706-2 · Cited by 35

Adverse Effects of Oxidative Stress on Bone and Vasculature in Corticosteroid-Associated Osteonecrosis: Potential Role of Nuclear Factor Erythroid 2-Related Factor 2 in Cytoprotection

Kubo, Y., Drescher, W., Fragoulis, A., Tohidnezhad, M., Jahr, H., Gatz, M., Driessen, A., Eschweiler, J., Tingart, M., Wruck, C. J., et al. (2021) · Antioxidants and Redox Signaling · doi:10.1089/ars.2020.8163 · Cited by 35

Galangin mitigates iron overload-triggered liver injury: Up-regulation of PPARγ and Nrf2 signaling, and abrogation of the inflammatory responses

Salama, S. A., & Elshafey, M. M. (2021) · Life Sciences · doi:10.1016/j.lfs.2021.119856 · Cited by 35

Reduced HO-1 Protein Expression is Associated with More Severe Neurodegeneration after Transient Ischemia Induced by Cortical Compression in Diabetic Goto—Kakizaki Rats

Moreira, T. J., Cebere, A., Cebers, G., Östenson, C., Efendić, S., & Liljequist, S. (2007) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1038/sj.jcbfm.9600479 · Cited by 35

Heme Oxygenase‐1 is Associated with Wheat Salinity Acclimation by Modulating Reactive Oxygen Species HomeostasisF

Xie, Y., Cui, W., Yuan, X., Shen, W., & Yang, Q. (2011) · Journal of Integrative Plant Biology · doi:10.1111/j.1744-7909.2011.01052.x · Cited by 35

In Vitro and In Vivo Neuroprotective Effects of Stellettin B Through Anti-Apoptosis and the Nrf2/HO-1 Pathway

Feng, C., Chen, N., Wen, Z., Yang, W.-Y., Kuo, H., Sung, P., Su, J., Cheng, S.-Y., & Chen, W.-F. (2019) · Marine Drugs · doi:10.3390/md17060315 · Cited by 34

Heme Oxygenase-1 as Therapeutic Target for Diabetic Foot Ulcers

Leal, E. C., & Carvalho, E. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms231912043 · Cited by 36

Heme oxygenase-1 is involved in the cytokinin-induced alleviation of senescence in detached wheat leaves during dark incubation

Huang, J., Han, B., Xu, S. B., Zhou, M., & Shen, W. (2010) · Journal of Plant Physiology · doi:10.1016/j.jplph.2010.10.010 · Cited by 34

Role of Carbon Monoxide in Vascular Diseases

Barbagallo, I. A., Marrazzo, G., Frigiola, A., Zappalà, A., & Volti, G. L. (2012) · Current Pharmaceutical Biotechnology · doi:10.2174/138920112800399086 · Cited by 33

Arctigenin alleviates cadmium-induced nephrotoxicity: Targeting endoplasmic reticulum stress, Nrf2 signaling, and the associated inflammatory response

Salama, S. A., Mohamadin, A. M., & Abdel‐Bakky, M. S. (2021) · Life Sciences · doi:10.1016/j.lfs.2021.120121 · Cited by 33

Curcumin ameliorates high glucose‐induced acute vascular endothelial dysfunction in rat thoracic aorta

Fang, X., Yang, F., Zhu, L., Shen, Y., Wang, L., & Chen, Y. (2009) · Clinical and Experimental Pharmacology and Physiology · doi:10.1111/j.1440-1681.2009.05210.x · Cited by 33

Edaravone Improves Septic Cardiac Function by Inducing an HIF‐1α/HO‐1 Pathway

He, C., Zhang, W., Li, S., Ruan, W., Xu, J., & Xiao, F. (2018) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2018/5216383 · Cited by 32

Resveratrol treatment modulates several antioxidant and anti-inflammatory genes expression and ameliorated oxidative stress mediated fibrosis in the kidneys of high-fat diet-fed rats

Chowdhury, F. I., Yasmin, T., Akter, R., Islam, M. N., Hossain, M. M., Khan, F., Aldhahrani, A., Soliman, M. M., Subhan, N., Haque, M. A., et al. (2022) · Saudi Pharmaceutical Journal · doi:10.1016/j.jsps.2022.07.006 · Cited by 32

Cobalt Protoporphyrin Induces HO-1 Expression Mediated Partially by FOXO1 and Reduces Mitochondria-Derived Reactive Oxygen Species Production

Liu, X., Cui, Y., Li, M., Xu, H. C., Zuo, J., Fang, F., & Chang, Y. (2013) · PLoS ONE · doi:10.1371/journal.pone.0080521 · Cited by 32

Does Glucagon-like Peptide-1 Ameliorate Oxidative Stress in Diabetes? Evidence Based on Experimental and Clinical Studies

Petersen, K. E., Rakipovski, G., Raun, K., & Lykkesfeldt, J. (2016) · Current Diabetes Reviews · doi:10.2174/1573399812666150918150608 · Cited by 35

Quercetin, but not rutin, attenuated hydrogen peroxide-induced cell damage via heme oxygenase-1 induction in endothelial cells

Tian, R., Yang, Z., Lu, N., & Peng, Y. (2019) · Archives of Biochemistry and Biophysics · doi:10.1016/j.abb.2019.108157 · Cited by 32

Effect of repeatedly heated palm olein on blood pressure-regulating enzymes activity and lipid peroxidation in rats.

Leong, X.-F., Salimon, J., Mustafa, M. R., & Jaarin, K. (2012) · Europe PMC (PubMed Central) · Cited by 30

Pro-healing potential of hemin: An inducer of heme oxygenase-1

Ahanger, A. A., Prawez, S., Leo, M. D., Kathirvel, K., Kumar, D., Tandan, S. K., & Malik, J. K. (2010) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2010.06.048 · Cited by 30

Erythropoietin regulates signaling pathways associated with neuroprotective events

Cornelio-Martínez, S., & Castañeda‐Arellano, R. (2022) · Experimental Brain Research · doi:10.1007/s00221-022-06331-9 · Cited by 29

Antihypertensive Actions of Moderate Hyperbilirubinemia: Role of Superoxide Inhibition

Stec, D. E., Storm, M. V., Pruett, B. E., & Gousset, M. (2013) · American Journal of Hypertension · doi:10.1093/ajh/hpt038 · Cited by 29

Effect of biologically active fraction of Nardostachys jatamansi on cerulein-induced acute pancreatitis.

Bae, G., Kim, M.-S., Park, K., Koo, B. S., Jo, I., Choi, S.-B., Lee, D., Kim, Y., Kim, T., Seo, S.-W., et al. (2012) · Europe PMC (PubMed Central) · doi:10.3748/wjg.v18.i25.3223 · Cited by 28

Water-Soluble Fullerenol C60(OH)36 toward Effective Anti-Air Pollution Induced by Urban Particulate Matter in HaCaT Cell

Lee, C., Chi, M., Peng, K., Chiang, Y., Hsu, L., Yan, Y., Li, H.-Y., Chen, M., Lee, I., & Lai, C. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20174259 · Cited by 26

Adrenic acid induces oxidative stress in hepatocytes

Zhao, J., Nishiumi, S., Tagawa, R., Yano, Y., Inoue, J., Hoshi, N., Yoshida, M., & Kodama, Y. (2020) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2020.08.102 · Cited by 27

Heme Arginate Suppresses Cardiac Lesions and Hypertrophy in Deoxycorticosterone Acetate-Salt Hypertension

Jadhav, A., & Ndisang, J. F. (2009) · Experimental Biology and Medicine · doi:10.3181/0810-rm-302 · Cited by 28

Ameliorative effects of silymarin on HCl-induced acute lung injury in rats; role of the Nrf-2/HO-1 pathway.

Ahmed, R. F., Moussa, R. A., EL-Demerdash, R. S., Zakaria, M. M., & Abdel-Gaber, S. A. (2019) · Europe PMC (PubMed Central) · doi:10.22038/ijbms.2019.14069 · Cited by 28

Metabolic syndrome and prostatic disease: potentially role of polyphenols in preventive strategies. A review

Castelli, T., Russo, G. I., Reale, G., Privitera, S., Chisari, M., Fragalà, E., Favilla, V., Cimino, S., & Morgia, G. (2016) · International braz j urol · doi:10.1590/s1677-5538.ibju.2015.0095 · Cited by 27

Upregulation of Heme Oxygenase-1 Combined with Increased Adiponectin Lowers Blood Pressure in Diabetic Spontaneously Hypertensive Rats through a Reduction in Endothelial Cell Dysfunction, Apoptosis and Oxidative Stress

Cao, J. J., Drummond, G., Inoue, K., Sodhi, K., Li, X. Y., & Omura, S. (2008) · International Journal of Molecular Sciences · doi:10.3390/ijms9122388 · Cited by 28

Heme oxygenase-1 is involved in ascorbic acid-induced alleviation of cadmium toxicity in root tissues of Medicago sativa

Jin, Q., Zhu, K., Xie, Y., & Shen, W. (2012) · Plant and Soil · doi:10.1007/s11104-012-1451-9 · Cited by 25

Combined carvacrol and cilostazol ameliorate ethanol-induced liver fibrosis in rats: Possible role of SIRT1/Nrf2/HO-1 pathway

Abu-Risha, S. E.-S., Sokar, S. S., Elbohoty, H. R., & El‐Sisi, A. E. (2023) · International Immunopharmacology · doi:10.1016/j.intimp.2023.109750 · Cited by 27

Heme oxygenase-1 induction modulates hypoxic pulmonary vasoconstriction through upregulation of ecSOD

Ahmad, M., Zhao, X., Kelly, M. R., Kandhi, S., Pérez, Ó., Abraham, N. G., & Wolin, M. S. (2009) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00315.2009 · Cited by 26

Glycofullerenes Inhibit Particulate Matter Induced Inflammation and Loss of Barrier Proteins in HaCaT Human Keratinocytes

Lee, C., Su, Y.-H., Chiang, Y., Lee, I., Li, S.-Y., Lee, H.-C., Hsu, L., Yan, Y., Li, H.-Y., Chen, M., et al. (2020) · Biomolecules · doi:10.3390/biom10040514 · Cited by 25

Acerola (Malpighia emarginata) Anti-Inflammatory Activity—A Review

Olędzki, R., & Harasym, J. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25042089 · Cited by 25

Hyperglycaemia exerts deleterious effects on late endothelial progenitor cell secretion actions

Zhang, J., Zhang, X., Li, H., Cui, X., Guan, X., Tang, K., Jin, C., & Cheng, M. (2012) · Diabetes and Vascular Disease Research · doi:10.1177/1479164112444639 · Cited by 25

Modification of Caffeic Acid with Pyrrolidine Enhances Antioxidant Ability by Activating AKT/HO-1 Pathway in Heart

Ku, H.-C., Lee, S.-Y., Yang, K., Kuo, Y., & Su, M. (2016) · PLoS ONE · doi:10.1371/journal.pone.0148545 · Cited by 25

Heme Oxygenase-1 Induction Does Not Improve Vascular Relaxation in Angiotensin II Hypertensive Mice

Stec, D. E., Vera, T., McLemore, G. R., Kelsen, S., Rimoldi, J. M., Gadepalli, R. S., & Ryan, M. J. (2008) · American Journal of Hypertension · doi:10.1038/ajh.2007.29 · Cited by 25

Andrographis paniculata diterpenoids and ethanolic extract inhibit TNFα-induced ICAM-1 expression in EA.hy926 cells

Lin, H.-C., Li, C., Yang, Y., Chiu, T.-H., Liu, K., Lii, C., & Chen, H. (2018) · Phytomedicine · doi:10.1016/j.phymed.2018.09.205 · Cited by 24

Chronic tempol treatment attenuates the renal hemodynamic effects induced by a heme oxygenase inhibitor in streptozotocin diabetic rats

Rodríguez, F., López, B., Perez, C., Fenoy, F. J., Hernández, I., Stec, D. E., Volti, G. L., & Salom, M. G. (2011) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00847.2010 · Cited by 24

ApoA1

Vanella, L., Li, M., Kim, D.-H., Malfa, G. A., Bellner, L., Kawakami, T., & Abraham, N. G. (2012) · Cell Cycle · doi:10.4161/cc.11.4.19125 · Cited by 23

Cytoprotective effects of erythropoietin: What about the lung?

Haine, L., Yegen, C.-H., Marchant, D., Richalet, J., Boncoeur, É., & Voituron, N. (2021) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2021.111547 · Cited by 23

Total serum bilirubin and 8-year incident type 2 diabetes mellitus: The Korean Genome and Epidemiology Study

Kwon, Y., Lee, Y., Park, B., Hong, K., & Jung, D. (2017) · Diabetes & Metabolism · doi:10.1016/j.diabet.2017.07.004 · Cited by 23

Induction of hemeoxygenase-1 attenuates the hypertension and renal inflammation in spontaneously hypertensive rats

Elmarakby, A. A., Faulkner, J., Posey, S. P., & Sullivan, J. C. (2010) · Pharmacological Research · doi:10.1016/j.phrs.2010.07.005 · Cited by 23

An overview of hyperbaric oxygen preconditioning against ischemic stroke

Wu, X., You, J., Chen, X., Zhou, M., Ma, H., Zhang, T., & Huang, C. (2023) · Metabolic Brain Disease · doi:10.1007/s11011-023-01165-y · Cited by 25

Targeting Endothelial Cells with Heme Oxygenase-1 Gene Using VE-Cadherin Promoter Attenuates Hyperglycemia-Mediated Cell Injury and Apoptosis

Asija, A., Peterson, S. J., Stec, D. E., & Abraham, N. G. (2007) · Antioxidants and Redox Signaling · doi:10.1089/ars.2007.1804 · Cited by 22

Differential Cellular Responses to Protein Adducts of Naphthoquinone and Monocrotaline Pyrrole

Wong, L. S. N., Lamé, M. W., Jones, A. D., & Wilson, D. W. (2010) · Chemical Research in Toxicology · doi:10.1021/tx1002436 · Cited by 21

New light on the anti-colitic actions of therapeutic aminosalicylates: the role of heme oxygenase

Whittle, B. J. R., & Varga, C. (2010) · Pharmacological Reports · doi:10.1016/s1734-1140(10)70312-1 · Cited by 21

Insulin-Induced Oxidative Stress Up-Regulates Heme Oxygenase-1 via Diverse Signaling Cascades in the C2 Skeletal Myoblast Cell Line

Aggeli, I.-K. S., Theofilatos, D., Beis, I. D., & Gaitanaki, C. (2011) · Endocrinology · doi:10.1210/en.2010-1319 · Cited by 21

Pinocembrin Attenuates Mitochondrial Dysfunction in Human Neuroblastoma SH-SY5Y Cells Exposed to Methylglyoxal: Role for the Erk1/2–Nrf2 Signaling Pathway

de Oliveira, M. R., Peres, A., & Ferreira, G. C. (2016) · Neurochemical Research · doi:10.1007/s11064-016-2140-5 · Cited by 21

Therapeutic approaches to diabetic cardiomyopathy: Targeting the antioxidant pathway

Arad, M., Waldman, M., Abraham, N. G., & Hochhauser, E. (2020) · Prostaglandins & Other Lipid Mediators · doi:10.1016/j.prostaglandins.2020.106454 · Cited by 20

Zinc protoporphyrin inhibition of lipopolysaccharide-, lipoteichoic acid-, and peptidoglycan-induced nitric oxide production through stimulating iNOS protein ubiquitination

Chow, J., Lin, H.-Y., Shen, S., Wu, M., Lin, C., Chiu, W., Lin, C., & Chen, Y. (2009) · Toxicology and Applied Pharmacology · doi:10.1016/j.taap.2009.04.009 · Cited by 20

Heme oxygenase-1 induction depletes heme and attenuates pulmonary artery relaxation and guanylate cyclase activation by nitric oxide

Mingone, C. J., Ahmad, M., Gupte, S. A., Chow, J. L., & Wolin, M. S. (2008) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00846.2007 · Cited by 20

Pravastatin improves fetal survival in mice with a partial deficiency of heme oxygenase-1

Tsur, A., Kalish, F. S., Burgess, J. J., Nayak, N. R., Zhao, H. F., Casey, K. M., Druzin, M. L., Wong, R. J., & Stevenson, D. K. (2018) · Placenta · doi:10.1016/j.placenta.2018.11.001 · Cited by 19

Andrographolide inhibits IL-1β release in bone marrow-derived macrophages and monocyte infiltration in mouse knee joints induced by monosodium urate

Lo, C., Lii, C., Hong, J.-J., Chuang, W.-T., Yang, Y., Huang, C., & Chen, H. (2020) · Toxicology and Applied Pharmacology · doi:10.1016/j.taap.2020.115341 · Cited by 19

Targeting SIRT1, NLRP3 inflammasome, and Nrf2 signaling with chrysin alleviates the iron-triggered hepatotoxicity in rats

Alanazi, S., Salama, S. A., Elebiary, A. M., Altowairqi, A. K., Alharthi, A. T., Alzahrani, S. M., Althagafi, S. H., Alotaibi, R. E., & Tammam, A. A.-E. (2024) · Toxicology · doi:10.1016/j.tox.2024.153766 · Cited by 18

Physiological and Pathological Roles of Free Radicals in Male Reproduction

Tvrdá, E., Massányi, P., & Lukáč, N. (2018) · InTech eBooks · doi:10.5772/intechopen.70793 · Cited by 20

Elderberries as a potential supplement to improve vascular function in a SARS‐CoV ‐2 environment

Festa, J., Singh, H., Hussain, A., & Boit, M. D. (2022) · Journal of Food Biochemistry · doi:10.1111/jfbc.14091 · Cited by 17

Atorvastatin Attenuates Radiotherapy‐Induced Intestinal Damage through Activation of Autophagy and Antioxidant Effects

Wei, M., Cheng, C.-H., Wen, S.-Y., Lin, J.-C., Chen, Y., Wang, C.-W., Lee, Y., & Kuo, S. (2022) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2022/7957255 · Cited by 18

The Ameliorative Effects of the Ethyl Acetate Extract ofSalicornia europaeaL. and Its Bioactive Candidate, Irilin B, on LPS-Induced Microglial Inflammation and MPTP-Intoxicated PD-Like Mouse Model

Kim, J.-S., Karthivashan, G., Kweon, M., Kim, D.-H., & Choi, D. (2019) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2019/6764756 · Cited by 19

Hyperoxia preconditioning: the next frontier in neurology?

Liu, W., Liu, K., Tao, H., Chen, C., Zhang, J. H., & Sun, X. (2012) · Neurological Research · doi:10.1179/1743132812y.0000000034 · Cited by 17

Antioxidant and Anti-Inflammatory Effects of Genus Gynura: A Systematic Review

Tan, J. N., Saffian, S. M., Buang, F., Jubri, Z., Jantan, I., Husain, K., & Fauzi, N. M. (2020) · Frontiers in Pharmacology · doi:10.3389/fphar.2020.504624 · Cited by 21

Ataxia telangiectasia mutated inhibits oxidative stress-induced apoptosis by regulating heme oxygenase-1 expression

Yu, J. H., Cho, S. O., Lim, J. W., Kim, N., & Kim, H. (2015) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/j.biocel.2015.01.002 · Cited by 16

The 1-Tosylpentan-3-one Protects against 6-Hydroxydopamine-Induced Neurotoxicity

Kao, C.-J., Chen, W.-F., Guo, B.-L., Feng, C., Hung, H.-C., Yang, W.-Y., Sung, C., Tsui, K., Chu, H., Chen, N., et al. (2017) · International Journal of Molecular Sciences · doi:10.3390/ijms18051096 · Cited by 16

Hemin, a heme oxygenase-1 inducer, improves aortic endothelial dysfunction in insulin resistant rats

Chen, Y., Zhu, X., Zhao, X., Xing, H., & Li, Y. (2008) · Chinese Medical Journal · doi:10.1097/00029330-200802010-00012 · Cited by 16

Heme-arginate suppresses phospholipase C and oxidative stress in the mesenteric arterioles of mineralcorticoid-induced hypertensive rats

Ndisang, J. F., & Jadhav, A. (2010) · Hypertension Research · doi:10.1038/hr.2010.1 · Cited by 15

Role of inflammation and oxidative stress in tissue damage associated with cystic fibrosis: CAPE as a future therapeutic strategy

Soares, V. E. M., do Carmo, T. I. T., dos Anjos, F., Wruck, J., Maciel, S. F. V. D. O., Bagatini, M. D., & Silva, D. T. D. R. E. (2021) · Molecular and Cellular Biochemistry · doi:10.1007/s11010-021-04263-6 · Cited by 17

7, 8-Dihydroxyflavone Protects an Endothelial Cell Line from H2O2 Damage

Wang, B., Zhang, Q., Yao, R., Liu, X., & Qu, Z. (2015) · PLoS ONE · doi:10.1371/journal.pone.0135345 · Cited by 15

Cobalt protoporphyrin inhibition of lipopolysaccharide or lipoteichoic acid-induced nitric oxide production via blocking c-Jun N-terminal kinase activation and nitric oxide enzyme activity

Lin, H.-Y., Shen, S., Lin, C., Wu, M., & Chen, Y. (2009) · Chemico-Biological Interactions · doi:10.1016/j.cbi.2009.01.004 · Cited by 15

Dysregulation of hypoxia-inducible factor-1α (Hif1α) expression in the Hmox1-deficient placenta

Zhao, H. F., Narasimhan, P., Kalish, F. S., Wong, R. J., & Stevenson, D. K. (2020) · Placenta · doi:10.1016/j.placenta.2020.07.015 · Cited by 15

Circularly Permuted Far-Red Fluorescent Proteins

Wu, T., Pang, Y., & Ai, H. (2021) · Biosensors · doi:10.3390/bios11110438 · Cited by 14

Modulating SIRT1, Nrf2, and NF-κB signaling pathways by bergenin ameliorates the cadmium-induced nephrotoxicity in rats

Alanazi, S., Harisa, G. I., & Salama, S. A. (2023) · Chemico-Biological Interactions · doi:10.1016/j.cbi.2023.110797 · Cited by 14

M3-mAChR Stimulation Exerts Anti-apoptotic Effect Via Activating the HIF-1α/HO-1/VEGF Signaling Pathway in H9c2 Rat Ventricular Cells

Hui, Y., Zhao, Y., Ma, N., Peng, Y., Pan, Z., Zou, C., Zhang, P., & Du, Z. (2012) · Journal of Cardiovascular Pharmacology · doi:10.1097/fjc.0b013e31826c1c13 · Cited by 15

Theaflavin alleviates cisplatin-induced nephrotoxicity: Targeting SIRT1/p53/FOXO3a/Nrf2 signaling and the NF-kB inflammatory cascade

Alanazi, S., Salama, S. A., Althobaiti, M. M., Bakhsh, A., Aljehani, N. M., Alanazi, E., Alanazi, M., & Musa, A. (2025) · Food and Chemical Toxicology · doi:10.1016/j.fct.2025.115334 · Cited by 12

Active Nrf2 signaling flexibly regulates HO-1 and NQO-1 in hypoxic Gansu Zokor (Eospalax cansus)

Li, M., Peng, Y., Chen, W., Gao, Y., Yang, M., Li, J., & He, J. (2022) · Comparative Biochemistry and Physiology Part B Biochemistry and Molecular Biology · doi:10.1016/j.cbpb.2022.110811 · Cited by 12

Tanshinone IIA suppresses burning incense-induced oxidative stress and inflammatory pathways in astrocytes

Chi, M., Lin, Z., Lee, C., Huang, C. C., Peng, K., Lin, C., Lee, H.-C., Fang, M.-L., & Chiang, Y. (2023) · Ecotoxicology and Environmental Safety · doi:10.1016/j.ecoenv.2023.114987 · Cited by 11

Lysimachiae Herba Inhibits Inflammatory Reactions and Improves Lipopolysaccharide/D-Galactosamine-Induced Hepatic Injury

Jeong, Y. H., Kim, T. I., Oh, Y.-C., & Yeul, J. (2021) · Antioxidants · doi:10.3390/antiox10091387 · Cited by 12

Heme oxygenase regulates renal arterial resistance and sodium excretion in cirrhotic rats

Pascoli, M. D., Zampieri, F., Quarta, S., Sacerdoti, D., Merkel, C., Gatta, A., & Bolognesi, M. (2010) · Journal of Hepatology · doi:10.1016/j.jhep.2010.08.013 · Cited by 11

Up-Regulation of Heme Oxygenase Provides Vascular Protection in an Animal Model of Diabetes through Its Antioxidant and Antiapoptotic Effects

Kruger, A. L., Peterson, S. J., Schwartzman, M. L., Fusco, H. N., McClung, J. A., Weiss, M. B., Shenouda, S. K., Goodman, A. I., Goligorsky, M. S., Kappas, A., et al. (2006) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.106.107482 · Cited by 109

Heme oxygenase-1 gene expression increases vascular relaxation and decreases inducible nitric oxide synthase in diabetic rats.

Movahedian, A., Türkseven, S., Mingone, C. J., Gupte, S. A., Wolin, M. S., & Abraham, N. G. (2005) · PubMed · Cited by 50

Up-regulation of heme oxygenase provides vascular protection in an animal model of diabetes through its antioxidant and antiapoptotic

Kruger, A. L., Peterson, S. J., Schwartzman, M. L., Fusco, H., Mcclung, J. A., Weiss, M., Shenouda, S., Goodman, A. I., Goligorsky, M. S., & Abraham, N. G. (2006)

Heme oxygenase-1 prevents superoxide anion-associated endothelial cell sloughing in diabetic rats

Quan, S., Kaminski, P. M., Yang, L. M., Morita, T., Inaba, M., Ikehara, S., Goodman, A. I., Wolin, M. S., & Abraham, N. G. (2004) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2004.01.086 · Cited by 78

Overexpression of human heme oxygenase-1 attenuates endothelial cell sloughing in experimental diabetes

Abraham, N. G., Rezzani, R., Rodella, L. F., Kruger, A. L., Taller, D., Volti, G. L., Goodman, A. I., & Kappas, A. (2004) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.01187.2003 · Cited by 110