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Assessment of parasympathetic control of heart rate by a noninvasive method
Abstract
The degree of parasympathetic control of heart rate was assessed by the abolition of respiratory sinus arrhythmia with atropine. Peak-to-peak variations in heart periods (VHP) before atropine injection correlated significantly (r = 0.90, P less than 0.001) with parasympathetic control, indicating that VHP alone may be used as a noninvasive indicator of the parasympathetic control of heart rate. Pharmacologic blockade of beta-adrenergic supply in a separate group of normal volunteers did not alter the relationship between VHP and parasympathetic control, indicating that the condition of the experiment (complete rest in a quiet atmosphere) allows the use of VHP alone without pharmacologic interventions to characterize the vagal control of heart rate in humans.
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Citations
Cited by
Heart rate variability: Standards of measurement, physiological interpretation, and clinical use
Malik, M., Bigger, J. T., Camm, A. J., Kleiger, R. E., Malliani, A., Moss, A. J., & Schwartz, P. J. (1996) · European Heart Journal · doi:10.1093/oxfordjournals.eurheartj.a014868 · Cited by 15,289
Pagani, M., Lombardi, F., Guzzetti, S., Rimoldi, O., Furlan, R., Pizzinelli, P., Sandrone, G., Malfatto, G., Dell'Orto, S., & Piccaluga, E. (1986) · Circulation Research · doi:10.1161/01.res.59.2.178 · Cited by 4,130
Heart rate variability: origins, methods, and interpretive caveats
BERNTSON, G. G., THOMAS BIGGER, J., ECKBERG, D. L., GROSSMAN, P., KAUFMANN, P. G., MALIK, M., NAGARAJA, H. N., PORGES, S. W., SAUL, J. P., STONE, P. H., et al. (1997) · Psychophysiology · doi:10.1111/j.1469-8986.1997.tb02140.x · Cited by 3,962
Frequency domain measures of heart period variability and mortality after myocardial infarction
Bigger, J. T., Fleiss, J. L., Steinman, R. C., Rolnitzky, L. M., Kleiger, R. E., & Rottman, J. N. (1992) · Circulation · doi:10.1161/01.cir.85.1.164 · Cited by 1,712
PORGES, S. W. (1995) · Psychophysiology · doi:10.1111/j.1469-8986.1995.tb01213.x · Cited by 1,624
Metadata
- Authors
- Fouad, F. M., Tarazi, R. C., Ferrario, C. M., Fighaly, S., & Alicandri, C.
- Venue
- American Journal of Physiology-Heart and Circulatory Physiology
- Publisher
- American Physiological Society
- Published
- 1984-06-01
- Volume
- 246
- Issue
- 6
- Pages
- H838-H842
- ISSN
- 0363-6135 (ISSN-L)
- 1522-1539
- OpenAlex
- W2336832375
- Cited by
- 309
- References
- 0
- FWCI
- 5.13
- Type
- journal article
- Language
- en
- Open access
- closed
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- Fouad, F. M., Tarazi, R. C., Ferrario, C. M., Fighaly, S., & Alicandri, C. (1984). Assessment of parasympathetic control of heart rate by a noninvasive method. American Journal of Physiology-Heart and Circulatory Physiology. https://doi.org/10.1152/ajpheart.1984.246.6.h838
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