The DOI matches its Crossref record.
Cardiac nucleotides in hypoxia: possible role in regulation of coronary blood flow
Abstract
Experiments were performed on isolated cat hearts perfused with Tyrode's solution and intact hearts of open-chest dogs. Cardiac hypoxia resulted in a decrease in coronary vascular resistance and a release of significant amounts of inosine and hypoxanthine from the myocardium. From 3 to 27 times more inosine and hypoxanthine were released from the heart during myocardial hypoxia than were required to double the coronary blood flow when infused as adenosine into the left coronary artery. Based on the assumption that with hypoxia the nucleotide derivatives leave the myocardial cell as adenosine, an hypothesis is proposed for the metabolic regulation of coronary blood flow.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cited by
Nomenclature and classification of purinoceptors.
Fredholm, B. B., Abbracchio, M. P., Burnstock, G., Daly, J. W., Harden, T. K., Jacobson, K. A., Leff, P., & Williams, M. (1994) · Pharmacological Reviews · doi:10.1016/s0031-6997(25)06782-1 · Cited by 1,585
Purinoceptors: Are there families of P2X and P2Y purinoceptors?
Abbracchio, M. P., & Burnstock, G. (1994) · Pharmacology & Therapeutics · doi:10.1016/0163-7258(94)00048-4 · Cited by 1,083
BERNE, R. M., RUBIO, R., & CURNISH, R. R. (1974) · Circulation Research · doi:10.1161/01.res.35.2.262 · Cited by 513
Self-citationCardiovascular effects of adenosine
Fredholm, B. B., & Sollevi, A. (1986) · Clinical Physiology · doi:10.1111/j.1475-097x.1986.tb00139.x · Cited by 115
Adenosine-Induced Vasoconstriction In Vivo: Role of the Mast Cell and A3Adenosine Receptor
Shepherd, R. K., Linden, J., & Duling, B. R. (1996) · Circulation Research · doi:10.1161/01.res.78.4.627 · Cited by 97
Metadata
- Authors
- Berne, R. M.
- Venue
- American Journal of Physiology-Legacy Content
- Publisher
- American Physiological Society
- Published
- 1963-02-01
- Volume
- 204
- Issue
- 2
- Pages
- 317-322
- ISSN
- 0002-9513 (ISSN-L)
- OpenAlex
- W1517594284
- Cited by
- 1,012
- References
- 0
- FWCI
- 13.32
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Cardiac nucleotides in hypoxia: possible role in regulation of coronary blood flow. https://app.cochat.ai/papers/10.1152/ajplegacy.1963.204.2.317
- The paper
- Berne, R. M. (1963). Cardiac nucleotides in hypoxia: possible role in regulation of coronary blood flow. American Journal of Physiology-Legacy Content. https://doi.org/10.1152/ajplegacy.1963.204.2.317
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
