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Circadian rhythm in sweating and cutaneous blood flow
Abstract
To characterize the changes in the control of the heat loss responses associated with the circadian variation in body temperature, we studied five men during 20 min of exercise in 25 degrees C on 6 separate days. Experiments were conducted at six times, equally spaced over the 24-h day. Esophageal temperature (Tes) and chest sweat rate (msw) were measured continuously, and forearm blood flow (FBF) was measured one to two times per minute. The thresholds for sweating and forearm vasodilation were significantly higher at 1600 and 2000 than at 2400 and 0400, averaging 0.57 and 0.65 degrees C higher, respectively, at 1600 than at 0400. Resting Tes and the Tes thresholds for cutaneous vasodilation and sweating during exercise all showed a similar circadian rhythm. The level at which core temperature is regulated therefore varies over the 24-h day with the zenith occurring around 1600 and the nadir at 0400. However, whereas the slope of the msw-to-Tes relation did not change over the 24-h day, the slope of the FBF-to-Tes relation tended to increase between 0400 and 2400, implying that the circadian rhythm may be more complex than just a shift in the central reference temperature.
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“The circadian clock regulates diurnal variations in autonomic thermoregulatory processes such as core body temperature in humans.”
From Human thermal perception and time of day: A review (2021) · cites this paper as [3]
In the citing paper
“During the night, the internal temperature thresholds for sweating and vasodilation have been shown to be lower than during the day, while the differences observed between the morning and the afternoon are smaller [1–3,51].”
From Human thermal perception and time of day: A review (2021) · cites this paper as [3]
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“Given the juxtaposition of the medial preoptic area to the suprachiasmatic nucleus of the hypothalamus, there is a circadian rhythm of body temperature in which the threshold for the onset of sweating is lowest around 2 am [17].”
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“[5] demonstrated that the thresholds for sweating and forearm vasodilation were significantly higher at 16 h: 00 and 20 h: 00 than at 24 h: 00 and 04 h: 00, but the zone did not change significantly over the 24-h day.”
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Chu, A. L. (2004) · Summit (Simon Fraser University) · Cited by 1
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thermoregulatory sweating threshold and sensitivity A simple and valid method to determine
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Metadata
- Authors
- Stephenson, L. A., Wenger, C. B., O'Donovan, B. H., & Nadel, E. R.
- Venue
- American Journal of Physiology-Regulatory, Integrative and Comparative Physiology
- Publisher
- American Physiological Society
- Published
- 1984-03-01
- Volume
- 246
- Issue
- 3
- Pages
- R321-R324
- ISSN
- 0363-6119 (ISSN-L)
- 1522-1490
- OpenAlex
- W2110741309
- Cited by
- 134
- References
- 0
- Citations by year
- 2026: 2 · 2025: 3 · 2022: 1 · 2021: 4 · 2020: 3 · 2019: 4 · 2018: 1 · 2017: 4 · 2016: 1 · 2015: 2 · 2014: 2 · 2013: 4 · 2012: 4
- FWCI
- 3.33
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- American Journal of Physiology-Regulatory, Integrative and Comparative Physiology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Physiology (medical) › Thermoregulation and physiological responses
- Health Sciences › Medicine › Physiology (medical) › Cardiovascular and exercise physiology
- Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Circadian rhythm and melatonin
- Keywords
- circadian rhythm, sweating, skin blood flow, heat loss, esophageal temperature, core body temperature, cutaneous vasodilation, exercise thermoregulation, sweat rate, forearm blood flow
- MeSH terms
- Adult, Arm, Body Temperature, Body Temperature Regulation, Circadian Rhythm, Differential Threshold, Esophagus, Humans, Male, Regional Blood Flow, Skin, Sweating, Vasodilation
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