Estrogen-induced modulation of hypothalamic osmoregulation in female rats

Estrogen treatment of ovariectomized female rats for a week decreased plasma osmolality from 294 to 278 mosmol/kgH2O, but recordings from the whole animal preparation under urethan anesthesia failed to detect any change in the activity of 76 vasopressinergic neurons in the supraoptic nucleus (SON…