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Cited by 297

The DOI matches its Crossref record; 131 of the 131 references it cites were found in a registry or an index.

Convective oxygen transport and fatigue

Open access
Amann, Markus, Calbet, Jose A. L.·2008·Journal of Applied Physiology
DOI 10.1152/japplphysiol.01008.2007
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Abstract

During exercise, fatigue is defined as a reversible reduction in force- or power-generating capacity and can be elicited by “central” and/or “peripheral” mechanisms. During skeletal muscle contractions, both aspects of fatigue may develop independent of alterations in convective O 2 delivery; however, reductions in O 2 supply exacerbate and increases attenuate the rate of accumulation. In this regard, peripheral fatigue development is mediated via the O 2 -dependent rate of accumulation of metabolic by-products (e.g., inorganic phosphate) and their interference with excitation-contraction coupling within the myocyte. In contrast, the development of O 2 -dependent central fatigue is elicited 1) by interference with the development of central command and/or 2) via inhibitory feedback on central motor drive secondary to the peripheral effects of low convective O 2 transport. Changes in convective O 2 delivery in the healthy human can result from modifications in arterial O 2 content, blood flow, or a combination of both, and they can be induced via heavy exercise even at sea level; these changes are exacerbated during acute and chronic exposure to altitude. This review focuses on the effects of changes in convective O 2 delivery on the development of central and peripheral fatigue.

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Metadata

Authors
Amann, M., & Calbet, J. A. L.
Venue
Journal of Applied Physiology
Publisher
American Physiological Society
Published
2008-03
Volume
104
Issue
3
Pages
861-870
ISSN
  • 0161-7567 (ISSN-L)
  • 8750-7587
  • 1522-1601
DOI
10.1152/japplphysiol.01008.2007
OpenAlex
W2047684905
Cited by
297
References
131
FWCI
26.65
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Convective oxygen transport and fatigue. https://app.cochat.ai/papers/10.1152/japplphysiol.01008.2007
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Amann, M., & Calbet, J. A. L. (2008). Convective oxygen transport and fatigue. Journal of Applied Physiology. https://doi.org/10.1152/japplphysiol.01008.2007

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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