Cited by 571Tactile and Sensory InteractionsIon Channels and ReceptorsPain Mechanisms and Treatments

The DOI matches its Crossref record; 45 of the 45 references it cites were found in a registry or an index.

Unmyelinated Afferents Constitute a Second System Coding Tactile Stimuli of the Human Hairy Skin

Vallbo, Å. B., Olausson, H., Wessberg, J.·1999·Journal of Neurophysiology

DOI 10.1152/jn.1999.81.6.2753

Open this paper in CoChat — free account

Abstract

Impulses were recorded from unmyelinated afferents innervating the forearm skin of human subjects using the technique of microneurography. Units responding to innocuous skin deformation were selected. The sample (n = 38) was split into low-threshold units (n = 27) and high-threshold units (n = 11) on the basis of three distinctive features, i.e., thresholds to skin deformation, size of response to innocuous skin deformation, and differential response to sharp and blunt stimuli. The low-threshold units provisionally were denoted tactile afferents on the basis of their response properties, which strongly suggest that they are coding some feature of tactile stimuli. They exhibited, in many respects, similar functional properties as described for low-threshold C-mechanoreceptive units in other mammals. However, a delayed acceleration, not previously demonstrated, was observed in response to long-lasting innocuous indentations. It was concluded that human hairy skin is innervated by a system of highly sensitive mechanoreceptive units with unmyelinated afferents akin to the system previously described in other mammals. The confirmation that the system is present in the forearm skin and not only in the face area where it first was identified suggests a largely general distribution although there are indications that the tactile C afferents may be lacking in the very distal parts of the limbs. The functional role of the system remains to be assessed although physiological properties of the sense organs invite to speculations that the slow tactile system might have closer relations to limbic functions than to cognitive and motor functions.

Integrity signals

Registry

Crossref · 10.1152/jn.1999.81.6.2753

Cites

45 of 45 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Applied Multivariate Statistical Analysis.
Johnson, A., & Wichern, D. W. (1988) · Biometrics · doi:10.2307/2531616 · Cited by 11,374
Handbook of Physiology.
Plum, F. (1960) · Archives of Neurology · doi:10.1001/archneur.1960.03840090124020 · Cited by 10,388
Principles of neural science
(1982) · Trends in Neurosciences · doi:10.1016/0166-2236(82)90076-5 · Cited by 9,150
Handbook of Sensory Physiology
Sanders, M. D. (1975) · British Journal of Ophthalmology · doi:10.1136/bjo.59.2.111-c · Cited by 7,166
The Nervous System
Taussig, M. (1991) · Routledge eBooks · doi:10.4324/9780203397244 · Cited by 2,403
Somatosensory, proprioceptive, and sympathetic activity in human peripheral nerves
Vallbo, A. B., Hagbarth, K. E., Torebjork, H. E., & Wallin, B. G. (1979) · Physiological Reviews · doi:10.1152/physrev.1979.59.4.919 · Cited by 1,507
Self-citation
Response of cutaneous sensory units with unmyelinated fibers to noxious stimuli.
Bessou, P., & Perl, E. R. (1969) · Journal of Neurophysiology · doi:10.1152/jn.1969.32.6.1025 · Cited by 1,017
Cutaneous Mechanoreceptors and Nociceptors
Burgess, P. R., & Perl, E. R. (1973) · Handbook of sensory physiology · doi:10.1007/978-3-642-65438-1_3 · Cited by 568
Novel classes of responsive and unresponsive C nociceptors in human skin
Schmidt, R., Schmelz, M., Forster, C., Ringkamp, M., Torebjörk, E. H., & Handwerker, H. O. (1995) · Journal of Neuroscience · doi:10.1523/jneurosci.15-01-00333.1995 · Cited by 504
Touch, pain and tickling: an electro‐physiological investigation on cutaneous sensory nerves
Zotterman, Y. (1939) · The Journal of Physiology · doi:10.1113/jphysiol.1939.sp003707 · Cited by 484

Show all 45 references

Research works printed but not linked: 1

Kumazawa T., 1977, J. Physiol. (Paris), 73, 287

Sorted by citations

Items 301–400 of 562

Modeling affective touch pleasantness across skin types at the individual level reveals a reliable and stable basic function
Crucianelli, L., Chancel, M., & Ehrsson, H. H. (2022) · Journal of Neurophysiology · doi:10.1152/jn.00179.2022 · Cited by 17
Atypical Response to Affective Touch in Children with Autism: Multi-Parametric Exploration of the Autonomic System
Bufo, M. R., Guidotti, M., Mofid, Y., Malvy, J., Bonnet‐Brilhault, F., Aguillon-Hernandez, N., & Wardak, C. (2022) · Journal of Clinical Medicine · doi:10.3390/jcm11237146 · Cited by 19
Dissociable sources of erogeneity in social touch: Imagining and perceiving C-Tactile optimal touch in erogenous zones
Panagiotopoulou, E., Filippetti, M. L., Gentsch, A., & Fotopoulou, A. (2018) · PLoS ONE · doi:10.1371/journal.pone.0203039 · Cited by 17
The neural bases of tactile vitality forms and their modulation by social context
Rizzolatti, G., D’Alessio, A., Marchi, M., & Cesare, G. D. (2021) · Scientific Reports · doi:10.1038/s41598-021-87919-z · Cited by 17
Do C-tactile afferents go to sleep? A potential role for somatosensory stimulation in sleep regulation
Puyvelde, M. V., & Maîresse, O. (2021) · Current Opinion in Behavioral Sciences · doi:10.1016/j.cobeha.2021.08.006 · Cited by 17
Editorial overview: Affective touch: neurobiology and function
Schirmer, A., & McGlone, F. P. (2022) · Current Opinion in Behavioral Sciences · doi:10.1016/j.cobeha.2022.101129 · Cited by 17
The off-line effect of affective touch on multisensory integration and tactile perceptual accuracy during the somatic signal detection task
Sacchetti, S., McGlone, F., Cazzato, V., & Mirams, L. (2021) · PLoS ONE · doi:10.1371/journal.pone.0261060 · Cited by 16
Vicarious ratings of social touch the effect of age and autistic traits
Haggarty, C. J., Moore, D., Trotter, P. D., Hagan, R., McGlone, F. P., & Walker, S. C. (2021) · Scientific Reports · doi:10.1038/s41598-021-98802-2 · Cited by 16
An investigation into the peripheral substrates involved in the tactile modulation of cutaneous pain with emphasis on the C-tactile fibres
Mahns, D. A., & Nagi, S. S. (2013) · Experimental Brain Research · doi:10.1007/s00221-013-3521-5 · Cited by 16
Functional Organization of Dorsal Horn Interneurons
Willis, W. D., & Coggeshall, R. E. (2004) · Springer eBooks · doi:10.1007/978-1-4615-0037-7_7 · Cited by 16
Vascular and Neural Response to Focal Vibration, Sensory Feedback, and Piezo Ion Channel Signaling
Penasso, H., Petersen, F., & Peternell, G. (2023) · Journal of Vascular Diseases · doi:10.3390/jvd2010006 · Cited by 17
Determinants for positive and negative experiences of interpersonal touch: context matters
Sailer, U., Friedrich, Y., Asgari, F., Hassenzahl, M., & Croy, I. (2024) · Cognition & Emotion · doi:10.1080/02699931.2024.2311800 · Cited by 16
An inhibitory interaction of human cortical responses to stimuli preferentially exciting Aδ or C fibers
Tran, T. D., Matre, D., & Casey, K. L. (2007) · Neuroscience · doi:10.1016/j.neuroscience.2007.11.050 · Cited by 15
Social touch and allostasis
Zoltowski, A. R., Failla, M. D., & Cascio, C. J. (2021) · Current Opinion in Behavioral Sciences · doi:10.1016/j.cobeha.2021.08.005 · Cited by 16
You can touch this! Brain correlates of aesthetic processing of active fingertip exploration of material surfaces
Marschallek, B. E., Löw, A., & Jacobsen, T. (2023) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2023.108520 · Cited by 16
Mechanical allodynia generated by stimulation of unmyelinated afferent nerve fibres
Jänig, W. (2011) · The Journal of Physiology · doi:10.1113/jphysiol.2011.217083 · Cited by 15
Study of Physiological Parameters and Comfort Sensations During Friction Contacts of the Human Skin
Li, W., Pang, Q., Jiang, Y., Zhai, Z., & Zhou, Z. (2012) · Tribology Letters · doi:10.1007/s11249-012-0023-8 · Cited by 15
Affect-Gating
King, D., & Janiszewski, C. A. (2011) · Journal of Consumer Research · doi:10.1086/660811 · Cited by 15
Evolutionarily conserved neural responses to affective touch in monkeys transcend consciousness and change with age
Charbonneau, J. A., Santistevan, A. C., Raven, E. P., Bennett, J. L., Russ, B. E., & Bliss‐Moreau, E. (2024) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2322157121 · Cited by 14
The cognition of caused-motion events in Spanish and German: An Agentive Cognitive Construction Grammar analysis
Torres–Martínez, S. (2021) · Australian Journal of Linguistics · doi:10.1080/07268602.2021.1888279 · Cited by 14
Quantitative assessment of friction perception for fingertip touching with different roughness surface
Li, W., Zhan, M. L., Yu, Q., Zhang, B. Y., & Zhou, Z. (2015) · Biosurface and Biotribology · doi:10.1016/j.bsbt.2015.11.004 · Cited by 14
From Human-to-Human Touch to Peripheral Nerve Responses
Hauser, S. C., Nagi, S. S., McIntyre, S., Israr, A., Olausson, H., & Gerling, G. J. (2019) · IEEE World Haptics Conference (WHC) · doi:10.1109/whc.2019.8816113 · Cited by 14
Self-citation
The Neural Mechanisms of Touch and Proprioception at the Somatosensory Periphery
Goodman, J. M., & Bensmaı̈a, S. J. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-805408-6.00014-2 · Cited by 14
Haptic and Somesthetic Communication in Sexual Medicine
Moscatelli, A., Nimbi, F. M., Ciotti, S., & Jannini, E. A. (2020) · Sexual Medicine Reviews · doi:10.1016/j.sxmr.2020.02.003 · Cited by 14
Activity-dependent slowing properties of an unmyelinated low threshold mechanoreceptor in human hairy skin
Campero, M., Bostock, H., Baumann, T., & Ochoa, J. L. (2011) · Neuroscience Letters · doi:10.1016/j.neulet.2011.02.012 · Cited by 14
To touch or to be touched? comparing appraisal of vicarious execution and reception of interpersonal touch
Butti, N., Urgesi, C., McGlone, F. P., Oldrati, V., Montirosso, R., & Cazzato, V. (2024) · PLoS ONE · doi:10.1371/journal.pone.0293164 · Cited by 13
Affective Touching
Paterson, M. W. D. (2025) · Cambridge University Press eBooks · doi:10.1017/9781009484404 · Cited by 13
Italian Validation of the Touch Avoidance Measure and the Touch Avoidance Questionnaire
Casetta, L., Rizzi, L., Passarelli, M., Arcara, G., & Perrella, R. (2020) · Frontiers in Psychology · doi:10.3389/fpsyg.2020.01673 · Cited by 13
Wearable Haptics for Object Compliance Discrimination Through Passive Touch
D’Aurizio, N., Baldi, T. L., Villani, A., Minamizawa, K., Tanaka, Y., & Prattichizzo, D. (2021) · IEEE World Haptics Conference (WHC) · doi:10.1109/whc49131.2021.9517143 · Cited by 14
Chapter 29 Microneurography in the assessment of neuropathic pain
Jørum, E., & Schmelz, M. (2006) · Handbook of clinical neurology · doi:10.1016/s0072-9752(06)80033-3 · Cited by 13
Emotional visual stimuli affect the evaluation of tactile stimuli presented on the arms but not the related electrodermal responses
Etzi, R., Zampini, M., Juravle, G., & Gallace, A. (2018) · Experimental Brain Research · doi:10.1007/s00221-018-5386-0 · Cited by 14
The role of affective touch in whole-body embodiment remains equivocal
Carey, M., Crucianelli, L., Preston, C., & Fotopoulou, A. (2020) · Consciousness and Cognition · doi:10.1016/j.concog.2020.103059 · Cited by 13
Can Male Mice Develop Preference Towards Gentle Stroking by an Experimenter?
Cho, C., Chan, C., & Martin, L. J. (2020) · Neuroscience · doi:10.1016/j.neuroscience.2020.12.017 · Cited by 13
Functional Properties of C-Low Threshold Mechanoreceptors (C-LTMRs) in Nonhuman Mammals
Pitcher, M., Le Pichon, C. E., & Chesler, A. (2016) · Affective Touch and the Neurophysiology of CT Afferents · doi:10.1007/978-1-4939-6418-5_2 · Cited by 12
Receiving a Mediated Touch From Your Partner vs. a Male Stranger: How Visual Feedback of Touch and Its Sender Influence Touch Experience
Askari, S. I., Harjunen, V. J., Spapé, M., Haans, A., Ravaja, N., & IJsselsteijn, W. A. (2021) · IEEE Transactions on Affective Computing · doi:10.1109/taffc.2021.3085185 · Cited by 12
The role of affective touch in modulating emotion processing among preschool children
Longa, L. D., Carnevali, L., & Farroni, T. (2023) · Journal of Experimental Child Psychology · doi:10.1016/j.jecp.2023.105726 · Cited by 17
Mechanoreceptive Aβ Primary Afferents Discriminate Naturalistic Social Touch Inputs at a Functionally Relevant Time Scale
Xu, S., Hauser, S. C., Nagi, S. S., Jablonski, J. A., Rezaei, M., Jarocka, E., Marshall, A. G., Olausson, H., McIntyre, S., & Gerling, G. J. (2024) · IEEE Transactions on Affective Computing · doi:10.1109/taffc.2024.3435060 · Cited by 12
Self-citation
The Neurophysiological Impact of Touch-Based Therapy: Insights and Clinical Benefits
Bonanno, M., Papa, G. F. S., & Calabrò, R. S. (2024) · Journal of Integrative Neuroscience · doi:10.31083/j.jin2312214 · Cited by 13
Intrinsic and synaptic properties of adult mouse spinoperiaqueductal gray neurons and the influence of neonatal tissue damage
Li, J., Serafin, E. K., & Baccei, M. L. (2022) · Pain · doi:10.1097/j.pain.0000000000002787 · Cited by 12
Brain cognitive comparison of fabric touch on human glabrous and hairy skin
Wang, Q., Yu, W., Chen, K., Zhang, Z., & Asad, R. A. M. (2015) · Textile Research Journal · doi:10.1177/0040517515591785 · Cited by 12
Affective Touch and Human Grooming Behaviours: Feeling Good and Looking Good
McGlone, F. P., Walker, S. C., & Ackerley, R. (2016) · Springer eBooks · doi:10.1007/978-1-4939-6418-5_16 · Cited by 12
Touch-induced face conditioning is mediated by genetic variation in opioid but not oxytocin receptors
Fu, Y., Selçuk, E., Moore, S. R., & Depue, R. A. (2018) · Scientific Reports · doi:10.1038/s41598-018-27199-2 · Cited by 12
Thin Films on the Skin, but not Frictional Agents, Attenuate the Percept of Pleasantness to Brushed Stimuli
Rezaei, M., Nagi, S. S., Xu, C., McIntyre, S., Olausson, H., & Gerling, G. J. (2021) · IEEE World Haptics Conference (WHC) · doi:10.1109/whc49131.2021.9517259 · Cited by 12
Self-citation
Depression severity is associated with reduced pleasantness of observed social touch and fewer current intimate touch experiences
Tinker, V. C., Trotter, P. D., & Krahé, C. (2023) · PLoS ONE · doi:10.1371/journal.pone.0289226 · Cited by 11
Simulating the psychological and neural effects of affective touch with soft robotics: an experimental study
Zheng, C. Y., Wang, K.-J., Wairagkar, M., Mohr, M. V., Lintunen, E. M., & Fotopoulou, A. (2024) · Frontiers in Robotics and AI · doi:10.3389/frobt.2024.1419262 · Cited by 11
Characterizing affiliative touch in humans and its role in advancing haptic design
Kryklywy, J. H., Vyas, P., MacLean, K. E., & Todd, R. M. (2023) · Annals of the New York Academy of Sciences · doi:10.1111/nyas.15056 · Cited by 11
Slow touch and ultrafast pain fibres: Revisiting peripheral nerve classification
Olausson, H., Marshall, A. G., Nagi, S. S., & Cole, J. D. (2024) · Clinical Neurophysiology · doi:10.1016/j.clinph.2024.04.008 · Cited by 15
Self-citation
Autonomic Modulations to Cardiac Dynamics in Response to Affective Touch: Differences Between Social Touch and Self-Touch
Candia‐Rivera, D., Boehme, R., & Salamone, P. (2025) · IEEE Transactions on Affective Computing · doi:10.1109/taffc.2025.3548778 · Cited by 12
Stroking hardness changes the perception of affective touch pleasantness across different skin sites
Yu, J., Yang, J., Yu, Y., Wu, Q., Takahashi, S., Ejima, Y., & Wu, J. (2019) · Heliyon · doi:10.1016/j.heliyon.2019.e02141 · Cited by 11
Oxytocin Modulation of Spinal Circuits Drives Therapeutic Benefits of MassagePreprint
Bohic, M., Salamone, P., Zuo, W., Negm, A., Fulton, S. L., Du, S., Jayakumar, S., Keating, J., Soubeyre, V., Gradwell, M. A., et al. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.01.11.698886 · Cited by 11
Self-citation
Velocity-tuning of somatosensory EEG predicts the pleasantness of gentle caress
Schirmer, A., Lai, O., Cham, C., & Lo, C. (2022) · NeuroImage · doi:10.1016/j.neuroimage.2022.119811 · Cited by 10
Physiological Characteristics of Second-Order Somatosensory Circuits in Spinal Cord and Brainstem
Willis, W. D. (2008) · Elsevier eBooks · doi:10.1016/b978-012370880-9.00348-0 · Cited by 10
Probing interoception via thermosensation: No specific relationships across multiple interoceptive sub-modalitiesPreprint
Crucianelli, L., Enmalm, A., & Ehrsson, H. H. (2021) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2021.03.04.433866 · Cited by 10
Effectiveness of craniosacral therapy, Bowen therapy, static touch and standard exercise program on sleep quality in fibromyalgia syndrome: A randomized controlled trial
Ughreja, R. A., Venkatesan, P., Gopalakrishna, D. B., Singh, Y. P., & Vani Lakshmi, R. (2024) · Journal of Chinese Integrative Medicine · doi:10.1016/j.joim.2024.06.003 · Cited by 10
Assessing sensorimotor control of the lumbopelvic-hip region using task-based functional MRI
Silfies, S. P., Beattie, P., Jordon, M., & Vendemia, J. M. C. (2020) · Journal of Neurophysiology · doi:10.1152/jn.00288.2019 · Cited by 9
Stimulus frequency-dependent inhibition of micturition contractions of the urinary bladder by electrical stimulation of afferent Aβ, Aδ, and C fibers in cutaneous branches of the pudendal nerve
Onda, A., Uchida, S., Suzuki, H., & Hotta, H. (2016) · The Journal of Physiological Sciences · doi:10.1007/s12576-016-0468-x · Cited by 9
Suppression of scratching-induced pleasurable sensation by compression nerve blocking and its association with itch relief
Mochizuki, H., Shevchenko, A., Nattkemper, L. A., Valdés‐Rodríguez, R., & Yosipovitch, G. (2017) · Itch · doi:10.1097/itx.0000000000000007 · Cited by 9
Assessment of experimental orofacial pain, pleasantness and unpleasantness via standardized psychophysical testing
Taneja, P., Olausson, H., Trulsson, M., Vase, L., Svensson, P. J., & Baad‐Hansen, L. (2019) · European Journal of Pain · doi:10.1002/ejp.1391 · Cited by 9
Self-citation
Imaging affective and non-affective touch processing in two-year-old children
Maria, A., Hirvi, P., Kotilahti, K. M., Heiskala, J., Tuulari, J. J., Karlsson, L., Karlsson, H., & Nissila, I. T. (2022) · NeuroImage · doi:10.1016/j.neuroimage.2022.118983 · Cited by 9
Social Touch: Its Mirror-like Responses and Implications in Neurological and Psychiatric Diseases
Grandi, L. C., & Bruni, S. (2023) · NeuroSci · doi:10.3390/neurosci4020012 · Cited by 9
Spinal Cord: Connections
Schoenen, J. E., & Grant, G. (2004) · Elsevier eBooks · doi:10.1016/b978-012547626-3/50009-0 · Cited by 9
Automated Nociceptive Withdrawal Reflex Measurements Reveal Normal Reflex Thresholds and Augmented Pain Ratings in Patients with Fibromyalgia
Ydrefors, J., Karlsson, T., Olausson, U. W., Ghafouri, B., Johansson, A., Olausson, H., Gerdle, B. U. C., & Nagi, S. S. (2020) · Journal of Clinical Medicine · doi:10.3390/jcm9061992 · Cited by 9
Self-citation
Cortical processing of lateral skin stretch stimulation in humans
Wasling, H. B., Lundblad, L. C., Löken, L. S., Wessberg, J., Fernström, K. W., Norrsell, U., & Olausson, H. (2008) · Experimental Brain Research · doi:10.1007/s00221-008-1454-1 · Cited by 9
Self-citation
Insecure Attachment, Oxytocinergic System and C-Tactile Fibers: An Integrative and Translational Pathophysiological Model of Fibromyalgia and Central Sensitivity Syndromes
Bruti, G., & Foggetti, P. (2024) · Biomedicines · doi:10.3390/biomedicines12081744 · Cited by 8
Research Progress on Neural Processing of Hand and Forearm Tactile Sensation: A Review Based on fMRI Research
Chen, H., Fu, S., Zhi, X., Wang, Y., Liu, F., Li, Y., Ren, F., Zhang, J., Ren, L., & Wang, Y. (2025) · Neuropsychiatric Disease and Treatment · doi:10.2147/ndt.s488059 · Cited by 8
Distinct Expression of Mas1-Related G-Protein-Coupled Receptor B4 in Dorsal Root and Trigeminal Ganglia—Implications for Altered Behaviors in Acid-Sensing Ion Channel 3-Deficient Mice
Huang, Y.-H., Chang, C.-Y., Chen, C., Yang, C.-D., & Sun, W. (2013) · Journal of Molecular Neuroscience · doi:10.1007/s12031-013-0070-0 · Cited by 8
Brain activity in response to the touch of a hand on the center of the back
Morita, I., Sakuma, S., Shimomura, J., Hayashi, N., & Toda, S. (2018) · PLoS ONE · doi:10.1371/journal.pone.0206451 · Cited by 8
A psychophysical and neuroimaging analysis of genital hedonic sensation in men
Ruesink, G. B., McGlone, F. P., Olausson, H., de Jong, C., Marsman, J.-B., Renken, R. J., & Georgiadis, J. R. (2022) · Scientific Reports · doi:10.1038/s41598-022-14020-4 · Cited by 8
Self-citation
Design of a Wearable Haptic Device to Mediate Affective Touch with a Matrix of Linear Actuators
Ferguson, N., Cansev, M. E., Dwivedi, A., & Beckerle, P. (2022) · Lecture notes in networks and systems · doi:10.1007/978-3-031-16281-7_48 · Cited by 8
The C-Tactile System and the Neurobiological Mechanisms of “Affective” Tactile Perception: The History of Discoveries and the Current State of Research
Алексеевич, В. А., Portnova, G. V., & McGlone, F. F. (2020) · Neuroscience and Behavioral Physiology · doi:10.1007/s11055-020-00916-z · Cited by 8
Knismesis: the aversive facet of tickle
Алексеевич, В. А., & Skorokhodov, I. V. (2022) · Current Opinion in Behavioral Sciences · doi:10.1016/j.cobeha.2021.11.007 · Cited by 8
Using Facial Electromyography to Assess Facial Muscle Reactions to Experienced and Observed Affective Touch in Humans
Ree, A., Morrison, I., Olausson, H., Sailer, U., Heilig, M. A., & Mayo, L. M. (2019) · Journal of Visualized Experiments · doi:10.3791/59228 · Cited by 8
Self-citation
The effects of massage velocity on heart rate and heart rate variability in healthy infants: A randomized crossover study
Kamiya, C., Miyake, A., Yamada, T., Ohmi, M., & Watanabe, H. (2021) · Infant Behavior and Development · doi:10.1016/j.infbeh.2021.101604 · Cited by 7
Cortical Response Variation with Social and Non-Social Affective Touch Processing in the Glabrous and Hairy Skin of the Leg: A Pilot fMRI Study
Mayorova, L. A., Portnova, G. V., & Skorokhodov, I. V. (2023) · Sensors · doi:10.3390/s23187881 · Cited by 7
Hush, little baby: The role of C-tactile afferents in babywearing infants with neonatal opioid withdrawal
Rankin, L., Grisham, L. M., & Ingbar, C. (2024) · Infant Behavior and Development · doi:10.1016/j.infbeh.2024.101960 · Cited by 7
The impact of touch on bonding and neurodevelopment
Bendas, J., & Croy, I. (2021) · Elsevier eBooks · doi:10.1016/b978-0-12-817986-4.00048-1 · Cited by 7
Feel-Good Requirements: Neurophysiological and Psychological Design Criteria of Affective Touch for (Assistive) Robots
Cansev, M. E., Nordheimer, D., Kirchner, E. A., & Beckerle, P. (2021) · Frontiers in Neurorobotics · doi:10.3389/fnbot.2021.661207 · Cited by 7
Semiosic Translation: a Bayesian-heuristic theory of translation and translating
Torres–Martínez, S. (2024) · Language and Semiotic Studies · doi:10.1515/lass-2023-0042 · Cited by 7
Intimacy; views from impairment and neuroscience
Cole, J. D. (2014) · Emotion, space and society · doi:10.1016/j.emospa.2014.01.001 · Cited by 7
Spontaneous and Stimulus-Evoked Respiratory Rate Elevation Corresponds to Development of Allodynia in Spinal Cord–Injured Rats
Noble, D. J., Martin, K. K., Parvin, S., & Garraway, S. M. (2018) · Journal of Neurotrauma · doi:10.1089/neu.2018.5936 · Cited by 7
Processing and transmission of affective touch in the spinal cord
Marshall, A. G. (2021) · Current Opinion in Behavioral Sciences · doi:10.1016/j.cobeha.2021.07.006 · Cited by 7
Virtual Touch: Sensing and Feeling with UltrasoundPreprint
Moore, W., Makdani, A. D., Frier, W., & McGlone, F. P. (2021) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2021.08.25.457633 · Cited by 8
Pleasant Touch
Vallbo, Å. B., Olausson, H., & Wessberg, J. (2009) · Elsevier eBooks · doi:10.1016/b978-008045046-9.01916-1 · Cited by 7
Self-citation
Infant neural sensitivity to affective touch is associated with maternal postpartum depression
Nance, M. G., Landsman, Z. T., Gerling, G. J., & Puglia, M. H. (2024) · Infant Behavior and Development · doi:10.1016/j.infbeh.2024.101980 · Cited by 6
Tactile Stimulation Early in Life and During Adulthood: A Natural Strategy to Prevent or Ameliorate Health Disturbances
Melo, Á. I., & Hoffman, K. L. (2024) · Integrated science · doi:10.1007/978-3-031-73061-0_7 · Cited by 6
Somatosensation and body perception: the integration of afferent signals in multisensory cognitive processes
Ackerley, R. (2023) · Elsevier eBooks · doi:10.1016/b978-0-323-99193-3.00007-6 · Cited by 6
Decomposing Neural Representational Patterns of Discriminatory and Hedonic Information during Somatosensory Stimulation
Kryklywy, J. H., Ehlers, M. R., Beukers, A. O., Moore, S. R., Todd, R. M., & Anderson, A. K. (2022) · eNeuro · doi:10.1523/eneuro.0274-22.2022 · Cited by 6
Organization of the central pain pathways
(2010) · Cambridge University Press eBooks · doi:10.1017/cbo9780511770579.003 · Cited by 6
Artificial fast-adapting mechanoreceptor based on carbon nanotube percolating network
Bounakoff, C., Hayward, V., Genest, J., Michaud, F., & Beauvais, J. (2022) · Scientific Reports · doi:10.1038/s41598-021-04483-2 · Cited by 6
Vertical contact forces affect vibration perception in human hairy skin
Schmidt, D., Schlee, G., Milani, T. L., & Germano, A. M. C. (2023) · PeerJ · doi:10.7717/peerj.15952 · Cited by 6
Human-Human and Human-Animal Interaction : Some Common Physiological and Psychological Effects
Handlin, L. (2010) · Cited by 6
Single-Unit Recordings of Afferent Human Peripheral Nerves by Microneurography
Torebjörk, E. H., & Schmelz, M. (2005) · Elsevier eBooks · doi:10.1016/b978-0-7216-9491-7.50041-7 · Cited by 6
Tactile C Fibers
Macefield, V. G. (2008) · Springer eBooks · doi:10.1007/978-3-540-29678-2_5865 · Cited by 6
Affective Tactility: Cross-Modal Translation from Natural Language to Procedural Height MapsPreprint
Harada, Y. (2026) · Research Square · doi:10.21203/rs.3.rs-8696852/v1 · Cited by 6
Does affective touch buffer emotional distress? Insights from subjective and physiological indices
Longa, L. D., Sarlo, M., & Farroni, T. (2025) · Social Cognitive and Affective Neuroscience · doi:10.1093/scan/nsaf090 · Cited by 5
MASSAG model: Towards an integrative neuroscience framework linking emotional trauma, pain, and mechanisms of force-based manipulations
Jinich‐Diamant, A., Albinni, B., Fishbein, J. N., Jacobson, E., Abraira, V. E., Hong, S., Korgan, A. C., Mazzieri, A. M., & Case, L. K. (2025) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2025.106517 · Cited by 5
Human Foot Outperforms the Hand in Mechanical Pain Discrimination
Ng, K. K. W., Lafee, O., Bouchatta, O., Makdani, A. D., Marshall, A. G., Olausson, H., McIntyre, S., & Nagi, S. S. (2024) · eNeuro · doi:10.1523/eneuro.0412-23.2024 · Cited by 5
Self-citation
In vivo calcium imaging reveals directional sensitivity of C‐low threshold mechanoreceptors
Semizoglou, E., Re, L. L., Middleton, S. J., Pérez-Sánchez, J., Tufarelli, T., Bennett, D., & Chisholm, K. I. (2025) · The Journal of Physiology · doi:10.1113/jp286631 · Cited by 5
Affective Touch via Haptic Interfaces: A Sequential Indentation Approach
Cansev, M. E., Kindermann, M., Bliek, A., & Beckerle, P. (2025) · IEEE Transactions on Affective Computing · doi:10.1109/taffc.2025.3565157 · Cited by 5
Slow touch in non-human species: translational research into the C-tactile (CT) afferent system
Watkins, R. H. (2021) · Current Opinion in Behavioral Sciences · doi:10.1016/j.cobeha.2021.10.010 · Cited by 5

Authors: Vallbo, Å. B., Olausson, H., & Wessberg, J.
Affiliations: University of Gothenburg (SE)
ORCID: Olausson, H.
Wessberg, J.
Venue: Journal of Neurophysiology
Publisher: American Physiological Society
Published: 1999-06-01
Volume: 81
Issue: 6
Pages: 2753-2763
ISSN: 0022-3077 (ISSN-L)
1522-1598
DOI: 10.1152/jn.1999.81.6.2753
OpenAlex: W1824892726
Cited by: 571
References: 45
Citations by year: 2026: 27 · 2025: 38 · 2024: 32 · 2023: 32 · 2022: 35 · 2021: 51 · 2020: 36 · 2019: 31 · 2018: 33 · 2017: 30 · 2016: 29 · 2015: 23 · 2014: 23 · 2013: 21 · 2012: 16
FWCI: 2.97
Type: journal article
Language: en
Open access: closed
Locations: Journal of Neurophysiology (publishedVersion)
PubMed (publishedVersion)
Topics: Life Sciences › Neuroscience › Cognitive Neuroscience › Tactile and Sensory Interactions
Life Sciences › Neuroscience › Sensory Systems › Ion Channels and Receptors
Health Sciences › Medicine › Physiology (medical) › Pain Mechanisms and Treatments
Keywords: unmyelinated afferents, tactile coding, hairy skin, mechanoreceptors, skin deformation, forearm skin, microneurography
MeSH terms: Adult, Female, Hair, Hot Temperature, Humans, Male, Mechanoreceptors, Myelin Sheath, Nerve Fibers, Neural Conduction, Neurons, Afferent, Physical Stimulation, Sensory Thresholds, Skin, Touch

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Unmyelinated Afferents Constitute a Second System Coding Tactile Stimuli of the Human Hairy Skin

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks