Circadian Rhythms, Aging, and Life Span in Mammals
Abstract
Resetting the circadian clock leads to well being and increased life span, whereas clock disruption is associated with aging and morbidity. Increased longevity and improved health can be achieved by different feeding regimens that reset circadian rhythms and may lead to better synchrony in metabolism and physiology. This review focuses on recent findings concerning the relationships between circadian rhythms, aging attenuation, and life-span extension in mammals.
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In adult mammals, chronic circadian disruption has diverse negative impacts on physical and mental health, including a shortened lifespan.
“In adult mammals, chronic circadian disruption has diverse negative impacts on physical and mental health6, 7, including a shortened lifespan8.”
From Maternal and Early-Life Circadian Disruption Have Long-Lasting Negative Consequences on Offspring Development and Adult Behavior in Mice (2017) · cites this paper as [8]
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References 201 · Cited by 156
- Authors
- Froy, O.
- Affiliations
- Hebrew University of Jerusalem (IL)
- Corresponding author
- Froy, Oren
- ORCID
- Froy, Oren
- Venue
- Physiology
- Publisher
- American Physiological Society
- Published
- 2011-08
- Volume
- 26
- Issue
- 4
- Pages
- 225-235
- ISSN
- 0886-1714 (ISSN-L)
- 1548-9213
- 1548-9221
- OpenAlex
- W2032381538
- Cited by
- 156
- References
- 201
- Citations by year
- 2026: 4 · 2025: 6 · 2024: 6 · 2023: 13 · 2022: 8 · 2021: 10 · 2020: 9 · 2019: 12 · 2018: 11 · 2017: 16 · 2016: 12 · 2015: 13 · 2014: 19 · 2013: 10 · 2012: 7
- FWCI
- 1.20
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Physiology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Circadian rhythm and melatonin
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Aging › Genetics, Aging, and Longevity in Model Organisms
- Health Sciences › Medicine › Physiology › Dietary Effects on Health
- Keywords
- circadian rhythm, aging, lifespan extension, feeding regimen, longevity, metabolism, mammals
- MeSH terms
- Aging, Animals, Circadian Rhythm, Feeding Behavior, Humans, Longevity, Mammals
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