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Cited by 27Receptor Mechanisms and SignalingMonoclonal and Polyclonal Antibodies ResearchCardiovascular, Neuropeptides, and Oxidative Stress Research

The DOI matches its Crossref record.

Activating Autoantibodies and Cardiovascular Disease

Luft, Friedrich C.·2013·Physiology
DOI 10.1152/physiol.00014.2013
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Abstract

Stimulating antibodies against G-protein-coupled receptors, including the β1- and β2-adrenergic receptors, the α1-adrenergic receptor, and the angiotensin II AT1 receptor, have been described, as well as activating antibodies directed at the platelet-derived growth factor receptor tyrosine kinase. Their existence and actions appear to be established. Lacking are mechanistic studies of receptor activation and translational studies to document receptor-stimulating antibodies as worthwhile therapeutic targets.

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Crossref · 10.1152/physiol.00014.2013

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Metadata

Authors
Luft, F. C.
Affiliations
Vanderbilt University (US)
Corresponding author
Luft, Friedrich C.
ORCID
Luft, Friedrich C.
Venue
Physiology
Publisher
American Physiological Society
Published
2013-07
Volume
28
Issue
4
Pages
254-261
ISSN
  • 0886-1714 (ISSN-L)
  • 1548-9213
  • 1548-9221
DOI
10.1152/physiol.00014.2013
OpenAlex
W2169301679
Cited by
27
References
0
Citations by year
2026: 1 · 2023: 4 · 2022: 1 · 2021: 1 · 2020: 2 · 2019: 7 · 2018: 1 · 2017: 2 · 2016: 3 · 2015: 2 · 2014: 2 · 2013: 1
FWCI
0.25
Type
journal article
Language
en
Open access
closed
Locations
  • Physiology (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Receptor Mechanisms and Signaling
  • Life Sciences › Immunology and Microbiology › Immunology › Monoclonal and Polyclonal Antibodies Research
  • Health Sciences › Medicine › Surgery › Cardiovascular, Neuropeptides, and Oxidative Stress Research
Keywords
G protein-coupled receptors, beta1-adrenergic receptor, beta2-adrenergic receptor, alpha1-adrenoceptors, angiotensin II type 1 receptor, cardiovascular disease, receptor activation, therapeutic target
MeSH terms
Amino Acid Sequence, Autoantibodies, Cardiovascular Diseases, Humans, Molecular Sequence Data, Receptors, Adrenergic, beta, Receptor, Angiotensin, Type 1, Translational Research, Biomedical

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