Cardiac remodeling in obesity

Abel, E. Dale, Litwin, Sheldon E., Sweeney, Gary·2008·Physiological Reviews

Cited by (737)

Items 201–300 of 737

  1. Myocardial structure, function and ischaemic tolerance in a rodent model of obesity with insulin resistance
    I. Wensley, Kris Salaveria, Andrew Cameron Bulmer, Daniel G. Donner, Eugene F. Du Toit · 2013 · Experimental Physiology
  2. MicroRNA Expression Signature Is Altered in the Cardiac Remodeling Induced by High Fat Diets
    Elaine Castilho Guedes, Gustavo S. França, Caroline Antunes Lino, Fernanda Christtanini Koyama, Luana do Nascimento Moreira, Juliana Gomes Alexandre, Maria Luiza Morais Barreto‐Chaves, Pedro A. F. Galante, Gabriela Placoná Diniz · 2015 · Journal of Cellular Physiology
  3. Impact of Smoking on Circulating Cardiac Troponin I Concentrations and Cardiovascular Events in the General Population
    Magnus Nakrem Lyngbakken, Julia Brox Skranes, James A. de Lemos, Ståle Nygård, Håvard Dalen, Kristian Hveem, Helge Rørvik Røsjø, Torbjørn Omland · 2016 · Circulation
  4. NLRP3 inflammasome deficiency attenuates metabolic disturbances involving alterations in the gut microbial profile in mice exposed to high fat diet
    Marina Sokolova, Kuan Yang, Simen Hyll Hansen, Mieke C. Louwe, Martin Kummen, Johannes R. Hov, Ivar Sjaastad, Rolf Kristian Berge, Bente Lise Halvorsen, Pål Aukrust et al. · 2020 · Scientific Reports
  5. Metabolic Remodeling in the Hypertrophic Heart
    John C. Chatham, Martin Elliot Young · 2012 · Circulation Research
  6. Skeletal Muscle as a Mediator of Interorgan Crosstalk During Exercise: Implications for Aging and Obesity
    Julia A. Shero, Maléne E. Lindholm, Marco F. Sandri, Kristin I. Stanford · 2025 · Circulation Research
  7. Inhibition of inflammation and oxidative stress by an imidazopyridine derivative X22 prevents heart injury from obesity
    Yuanyuan Qian, Yali Zhang, Peng Zhong, Kesong Peng, Zheng Xu, Xuemei Chen, Kongqin Lu, Gaozhi Chen, Xiaokun Li, Guang Liang · 2016 · Journal of Cellular and Molecular Medicine
  8. Abdominal obesity and hypertension: a double burden to the heart
    Paweł Krzesiński, Adam Stańczyk, Katarzyna Piotrowicz, Grzegorz Gerard Gielerak, Beata Uziębło‐Życzkowska, Andrzej Skrobowski · 2016 · Hypertension Research
  9. Dietary Interventions, Cardiovascular Aging, and Disease
    Hamed Mirzaei, Stefano Di Biase, Valter Daniel Longo · 2016 · Circulation Research
  10. The impact of body mass index on clinical outcomes after acute myocardial infarction
    Doron Aronson, Mithal Nassar, Taly Goldberg, Michael R. Kapeliovich, Haim Hammerman, Zaher S. Azzam · 2010 · International Journal of Cardiology
  11. Role of the brain melanocortins in blood pressure regulation
    do Carmo, Jussara M., da Silva, Alexandre A., Wang, Zhen, Fang, Taolin, Aberdein, Nicola, Perez de Lara, Cecilia E., Hall, John E. · 2017 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
  12. Ischemia-Reperfusion Injury Leads to Distinct Temporal Cardiac Remodeling in Normal versus Diabetic Mice
    Megumi Eguchi, Young Hwa Kim, Keon Wook Kang, Chi Young Shim, Yangsoo Jang, Thierry Dorval, Kwang Joon Kim, Gary Sweeney · 2012 · PLoS ONE
  13. Long-term obesity promotes alterations in diastolic function induced by reduction of phospholamban phosphorylation at serine-16 without affecting calcium handling
    Ana Paula Lima‐Leopoldo, André Soares Leopoldo, Danielle C. T. da Silva, André Ferreira do Nascimento, Dijon Henrique Salomé de Campos, Renata de Azevedo Melo Luvizotto, Adriana Fernandes de Deus, Paula Paccielli Freire, Alessandra Medeiros, Katashi Okoshi et al. · 2014 · Journal of Applied Physiology
  14. APPL1 transgenic mice are protected from high-fat diet-induced cardiac dysfunction
    Min S. Park, Donghai Wu, Tae‐Sik Park, Cheolsoo Choi, Ren‐Ke Li, Kenneth K.Y. Cheng, Aimin Xu, Gary Sweeney · 2013 · American Journal of Physiology-Endocrinology and Metabolism
  15. Adiponectin stimulates Rho-mediated actin cytoskeleton remodeling and glucose uptake via APPL1 in primary cardiomyocytes
    Rengasamy Palanivel, Riya Ganguly, Subat Turdi, Aimin Xu, Gary Sweeney · 2014 · Metabolism
  16. Myocardial metabolic alterations in mice with diet-induced atherosclerosis: linking sulfur amino acid and lipid metabolism
    Jueun Lee, Sunhee Jung, Nami Kim, Min‐Jeong Shin, Do Hyun Ryu, Geum‐Sook Hwang · 2017 · Scientific Reports
  17. Roselle is cardioprotective in diet-induced obesity rat model with myocardial infarction
    Lislivia-Yiang-Nee Si, Siti Aishah Mohd Ali, Jalifah Latip, Norsyahida Mohd Fauzi, Siti Balkis Budin, Satirah Zainalabidin · 2017 · Life Sciences
  18. Caloric restriction reverses left ventricular hypertrophy through the regulation of cardiac iron homeostasis in impaired leptin signaling mice
    Hyeong Seok An, Jong Youl Lee, Eun Bee Choi, Eun Ae Jeong, Hyun Joo Shin, Kyung Eun Kim, Kyung-Ah Park, Zhen Hua Jin, Jung Eun Lee, Jin Sin Koh et al. · 2020 · Scientific Reports
  19. Adiponectin induces interleukin‐6 production and activates STAT3 in adult mouse cardiac fibroblasts
    Wenqiang Liao, Changan Yu, Jianyan Wen, William W.-G. Jia, Li Geng, Yuan-nan Ke, Shumin Zhao, William B. Campell · 2008 · Biology of the Cell
  20. High-fructose and high-fat feeding correspondingly lead to the development of lysoPC-associated apoptotic cardiomyopathy and adrenergic signaling-related cardiac hypertrophy
    Jiung‐Pang Huang, Mei‐Ling Cheng, Chao‐Hung Wang, Ming‐Shi Shiao, Jan‐Kan Chen, Li‐Man Hung · 2016 · International Journal of Cardiology
  21. Age-related cardiovascular disease and the beneficial effects of calorie restriction
    Miranda M. Y. Sung, Jason R.B. Dyck · 2011 · Heart Failure Reviews
  22. Growth, Obesity, and Cardiac Structures in Early Childhood
    Layla L. de Jonge, Lennie M. van Osch-Gevers, Sten P. Willemsen, Eric A.P. Steegers, Albert Hofman D, Willem A. Helbing, Vincent W. V. Jaddoe · 2011 · Hypertension
  23. Obesity Cardiomyopathy: Pathophysiologic Factors and Nosologic Reevaluation
    Samit Bhatheja, Hemang B. Panchal, Héctor O. Ventura, Timir Kumar Paul · 2016 · The American Journal of the Medical Sciences
  24. Heart failure with preserved ejection fraction: A systemic disease linked to multiple comorbidities, targeting new therapeutic options
    Yves Juillière, Clément Venner, Laura Filippetti, Batric Popovic, Olivier Huttin, Christine Selton‐Suty · 2018 · Archives of cardiovascular diseases
  25. Threshold body mass index and sex-specific waist circumference for increased risk of heart failure with preserved ejection fraction
    Duncan John Campbell, Fei Fei Gong, Michael V Jelinek, Julian M. Castro, Jennifer M. Coller, Michele McGrady, Umberto Boffa, Louise M. Shiel, Danny Liew, Simon Stewart et al. · 2019 · European Journal of Preventive Cardiology
  26. Precocious Preclinical Cardiovascular Sonographic Markers in Metabolically Healthy and Unhealthy Childhood Obesity
    Domenico Corica, Lilia Oreto, Giorgia Pepe, Maria Pia Calabrò, Luca Longobardo, Letteria Anna Morabito, Giovanni Battista Pajno, Angela Alibrandi, Tommaso Aversa, Malgorzata Gabriela Wasniewska · 2020 · Frontiers in Endocrinology
  27. Adiponectin Increases LPL Activity via RhoA/ROCK-Mediated Actin Remodelling in Adult Rat Cardiomyocytes
    Riya Ganguly, Kristin Schram, Xiangping Fang, Minsuk Kim, Brian B. Rodrigues, Farah S. L. Thong, Gary Sweeney · 2010 · Endocrinology
  28. Mechanisms of coronary microvascular adaptation to obesity
    Zsolt A Bagi · 2009 · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology
  29. Role of Mitogen-Activated Protein Kinase Pathways in Multifactorial Adverse Cardiac Remodeling Associated with Metabolic Syndrome
    Mohamed Asrih, François Mach, Alessio Nencioni, Franco Dallegri, Alessandra Quercioli, Fabrizio Montecucco · 2013 · Mediators of Inflammation
  30. Pyridostigmine alleviates cardiac dysfunction via improving mitochondrial cristae shape in a mouse model of metabolic syndrome
    Run‐Qing Xue, Xiao‐Jiang Yu, Ming Fei Zhao, Man Xu, Qing Wu, Yan-Ling Cui, Si Yang, Dongling Li, Weijin Zang · 2019 · Free Radical Biology and Medicine
  31. Compound LM9, a novel MyD88 inhibitor, efficiently mitigates inflammatory responses and fibrosis in obesity-induced cardiomyopathy
    Xuyong Zheng, Chuchu Sun, Qian Liu, Xiaoyao Lu, Lili Fu, Guang Liang, Xiuhua Zhang, Gaozhi Chen · 2020 · Acta Pharmacologica Sinica
  32. Cardiac remodeling and subclinical left ventricular dysfunction in adults with uncomplicated obesity: a cardiovascular magnetic resonance study
    Jing Liu, Jing Li, Huaxia Pu, Wenzhang He, Xiaoyue Zhou, Nanwei Tong, Liqing Peng · 2021 · Quantitative Imaging in Medicine and Surgery
  33. Pressure Overload-Induced Cardiac Dysfunction in Aged Male Adiponectin Knockout Mice Is Associated With Autophagy Deficiency
    James W.S. Jahng, Subat Turdi, Vera Kovacevic, Keith Dadson, Ren‐Ke Li, Gary Sweeney · 2015 · Endocrinology
  34. Effects ofPolygonatum sibiricumrhizome ethanol extract in high-fat diet-fed mice
    Jong-Hee Ko, Hyuk-Sang Kwon, Jong‐Min Yoon, Jong-Su Yoo, Hyeon-Soo Jang, Jiyoung Kim, Seung-Woo Yeon, Jae‐Hoon Kang · 2014 · Pharmaceutical Biology
  35. Cardiac fibrosis and vascular remodeling are attenuated by metformin in obese rats
    Adriana K. Burlá, Núbia Souza Lobato, Zuleica Bruno Fortes, Wille Oigman, Mário Fritsch Neves · 2011 · International Journal of Cardiology
  36. Gastrointestinal Surgery for Obesity and Diabetes: Weight Loss and Control of Hyperglycemia
    Helen Heneghan, Steven E. Nissen, Philip R. Schauer · 2012 · Current Atherosclerosis Reports
  37. Adiponectin is required for cardiac MEF2 activation during pressure overload induced hypertrophy
    Keith Dadson, Subat Turdi, Sarah Hashemi, Jianzhong Zhao, Nazari Polidovitch, Sanja Beca, Peter H. Backx, John C. McDermott, Gary Sweeney · 2015 · Journal of Molecular and Cellular Cardiology
  38. Cardiac Dysfunction Induced by Obesity Is Not Related to β-Adrenergic System Impairment at the Receptor-Signalling Pathway
    Artur Junio Togneri Ferron, Bruno Barcellos Jacobsen, Paula Grippa Sant’Ana, Dijon Henrique Salomé de Campos, Loreta Casquel de Tomasi, Renata de Azevedo Melo Luvizotto, Antônio Carlos Cicogna, André Soares Leopoldo, Ana Paula Lima‐Leopoldo · 2015 · PLoS ONE
  39. Risk of cardiac tachyarrhythmia in patients with repaired tetralogy of Fallot: a multicenter cardiac MRI based study
    Niek E. G. Beurskens, Quint A. J. Hagdorn, Thomas M. Gorter, Rolf M.F. Berger, Karin Marianne Vermeulen, Joost P. van Melle, Tjark Ebels, George K. Lui, Scott R. Ceresnak, Frandics Pak Chan et al. · 2018 · International journal of cardiac imaging
  40. Understanding Obesity-Related High Output Heart Failure and Its Implications
    Qiuhua Shen, John B. Hiebert, Faith K. Rahman, Kathryn J. Krueger, Bhanu P Gupta, Janet D. Pierce · 2021 · International Journal of Heart Failure
  41. Isoginkgetin, a bioactive constituent from Ginkgo Biloba, protects against obesity-induced cardiomyopathy via enhancing Nrf2/ARE signaling
    Xiaoqian Wu, Jianrong Huang, Junyuan Tang, Yuling Sun, Guojun Zhao, Cuishi Yan, Zhenghong Liu, Wei Yi, Suowen Xu, Xiyong Yu · 2022 · Redox Biology
  42. Insulin Regulation of Myocardial Autophagy
    Christian Riehle, E. Dale Abel · 2014 · Circulation Journal
  43. Physical Activity, Obesity, and Subclinical Myocardial Damage
    Roberta Florido, Chiadi E. Ndumele, Lucia Kwak, Yuanjie Pang, Kunihiro Matsushita, Jennifer A. Schrack, Mariana Lazo, Vijay Nambi, Roger Scott Blumenthal, Aaron R. Folsom et al. · 2017 · JACC Heart Failure
  44. Changes in Body Weight and Composition Are Associated With Changes in Left Ventricular Geometry and Function in the General Population
    Marcello Ricardo Paulista Markus, Nicole L. Werner, Sabine Schipf, Ulrike Siewert‐Markus, Martin Bahls, Sebastian Edgar Baumeister, Henry Völzke, Stephan Burkhard Felix, Till Ittermann, Marcus Dörr · 2017 · Circulation Cardiovascular Imaging
  45. Landscape of heart proteome changes in a diet-induced obesity model
    Danielle Fernandes Vileigas, Victoria M. Harman, Paula Paccielli Freire, Cecília Lume de Carvalho Marciano, Paula Grippa Sant’Ana, Sérgio Luiz Borges de Souza, Gustavo Augusto Ferreira Mota, Vitor Luiz da Silva, Dijon Henrique Salomé de Campos, Carlos Roberto Padovani et al. · 2019 · Scientific Reports
  46. The Falconoid Luteolin Mitigates the Myocardial Inflammatory Response Induced by High-Carbohydrate/High-Fat Diet in Wistar Rats
    Nashwa Abu‐Elsaad, Amr El-Karef · 2017 · Inflammation
  47. Free fatty acid oxidation in insulin resistance and obesity.
    E. Dale Abel · 2010 · PubMed
  48. Targeting Autophagy in Obesity‐Associated Heart Disease
    Diana Castañeda, Mohanad H. Gabani, Soo Kyoung Choi, Quynh My Nguyen, Cheng Chen, Ayesha Mapara, Adam Kassan, Alexis A. González, Karima Ait‐Aissa, Modar Kassan · 2019 · Obesity
  49. Galangin Resolves Cardiometabolic Disorders through Modulation of AdipoR1, COX-2, and NF-κB Expression in Rats Fed a High-Fat Diet
    Patoomporn Prasatthong, Sariya Meephat, Siwayu Rattanakanokchai, Juthamas Khamseekaew, Sarawoot Bunbupha, Parichat Prachaney, Putcharawipa Maneesai, Poungrat Pakdeechote · 2021 · Antioxidants
  50. Heart Failure and Obesity in Adults: Pathophysiology, Clinical Manifestations and Management
    Martin Alpert, Harsh Agrawal, Kul B. Aggarwal, Senthil Kumar, Arun H. S. Kumar · 2014 · Current Heart Failure Reports
  51. Sexual dimorphism in obesity-mediated left ventricular hypertrophy
    Christian Böhm, Verena Benz, Markus Clemenz, Christiane Sprang, Beata Hoeft, Ulrich Kintscher, Anna Foryst‐Ludwig · 2013 · American Journal of Physiology-Heart and Circulatory Physiology
  52. The association of obstructive sleep apnea and left ventricular hypertrophy in obese and overweight children with history of elevated blood pressure
    Colleen E. Hanlon, Edem Binka, Jeffrey S. Garofano, Laura M. Sterni, Tammy McLoughlin Brady · 2019 · Journal of Clinical Hypertension
  53. Impact of obesity on day‐night differences in cardiac metabolism
    Sobuj Mia, Ravi Sonkar, Lamario J. Williams, Mary N. Latimer, Isabelle Robillard Frayne, Abhinav Diwan, Stuart J. Frank, Christine Des Rosiers, Martin Elliot Young · 2021 · The FASEB Journal
  54. Leptin protects cardiomyocytes from serum‐deprivation‐induced apoptosis by increasing anti‐oxidant defence
    Juan Zheng, Fang Ji, Yuanjun Yin, Xiaochen Wang, An‐Jing Ren, Jie Bai, Xuejun Sun, Wen‐Jun Yuan, Lin Li · 2010 · Clinical and Experimental Pharmacology and Physiology
  55. Favorable Changes in Arterial Elasticity, Left Ventricular Mass, and Diastolic Function After Significant Weight Loss Following Laparoscopic Sleeve Gastrectomy in Obese Individuals
    Madalina Elena Iancu, Cătălin Copăescu, Marinela Şerban, Carmen Ginghină · 2013 · Obesity Surgery
  56. Deletion of the metabolic transcriptional coactivator PGC1β induces cardiac arrhythmia
    Iman Singh Gurung, Gema Medina‐Gómez, Adrienn Kis, Michael Baker, Vidya Velagapudi, Sudeshna Guha Neogi, Mark Campbell, Sergio Rodríguez‐Cuenca, Christopher J. Lelliott, Ian McFarlane et al. · 2011 · Cardiovascular Research
  57. Effect of Overweight and Obesity (Defined by Asian-Specific Cutoff Criteria) on Left Ventricular Diastolic Function and Structure in a General Korean Population
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  58. Cardiovascular, Kidney, Liver, and Metabolic Interactions in Heart Failure: Breaking Down Silos
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  59. Cardiomyocyte-specific knockout of endothelin receptor a attenuates obesity cardiomyopathy
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  60. Neuroendocrine and Cardiac Metabolic Dysfunction and NLRP3 Inflammasome Activation in Adipose Tissue and Pancreas following Chronic Spinal Cord Injury in the Mouse
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  61. The myocardial contractile response to physiological stress improves with high saturated fat feeding in heart failure
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  62. Ventricular remodelling in rabbits with sustained high‐fat diet
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  63. Local Application of Leptin Antagonist Attenuates Angiotensin II–Induced Ascending Aortic Aneurysm and Cardiac Remodeling
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  64. Obesity is a common soil for premature cardiac aging and heart diseases - Role of autophagy
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  65. An adiponectin-S1P axis protects against lipid induced insulin resistance and cardiomyocyte cell death via reduction of oxidative stress
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  66. SIRT3 Ablation Deteriorates Obesity-Related Cardiac Remodeling by Modulating ROS-NF-κB-MCP-1 Signaling Pathway
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  69. Cellular, structural and functional cardiac remodelling following pressure overload and unloading
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  70. Cluster Differentiating 36 (CD36) Deficiency Attenuates Obesity-Associated Oxidative Stress in the Heart
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  71. Loss of MD1 increases vulnerability to ventricular arrhythmia in diet-induced obesity mice via enhanced activation of the TLR4/MyD88/CaMKII signaling pathway
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  75. Therapy with mesenchymal stromal cells or conditioned medium reverse cardiac alterations in a high-fat diet–induced obesity model
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  76. High fat diet aggravates atrial and ventricular remodeling of hypertensive heart disease in aging rats
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  77. Transcriptome profiling reveals novel BMI- and sex-specific gene expression signatures for human cardiac hypertrophy
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  78. Association between Cardiac Remodeling and Metabolic Alteration in an Experimental Model of Obesity Induced by Western Diet
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  79. Obesity in pregnancy causes a volume overload in third trimester
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  80. Impaired contractile function and mitochondrial respiratory capacity in response to oxygen deprivation in a rat model of pre‐diabetes
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  81. Obesity and Burns
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  82. Obese phenotype and natriuretic peptides in patients with heart failure with preserved ejection fraction
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  83. Early changes of left ventricular geometry and deformational analysis in obese subjects without cardiovascular risk factors: a three-dimensional and speckle tracking echocardiographic study
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  84. Associations of childhood and adult obesity with left ventricular structure and function
    Huiqin Yang, Quan Long Huynh, Alison Venn, Terence Dwyer, Thomas Hugh Marwick · 2016 · International Journal of Obesity
  85. Sonic hedgehog signaling regulates hypoxia/reoxygenation‑induced H9C2 myocardial cell apoptosis
    Rui‐Ying Zhang, Zengyong Qiao, Huajin Liu, Jiang‑Wei Ma · 2018 · Experimental and Therapeutic Medicine
  86. Gender Differences in Cardiac Remodeling Induced by a High-Fat Diet and Lifelong, Low-Dose Cadmium Exposure
    Yaqin Liang, Jamie Lynn Young, Maiying Kong, Yongguang Tong, Yan Qian, Jonathan H. Freedman, Lu Cai · 2019 · Chemical Research in Toxicology
  87. Cardiovascular Imaging in Obesity
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  88. The impact of bariatric surgery on renal and cardiac functions in morbidly obese patients
    María Luaces, Ernesto Martínez‐Martínez, M. Medina, María Miana, N. Gonzalez, Cristina Fernández, Victoria Cachofeiro · 2012 · Nephrology Dialysis Transplantation
  89. Coenzyme A–mediated degradation of pyruvate dehydrogenase kinase 4 promotes cardiac metabolic flexibility after high-fat feeding in mice
    Christopher M. Schafer, Zachary T. Young, Catherine A. Makarewich, Abdallah Elnwasany, Caroline S. Kinter, Michael T Kinter, Luke I. Szweda · 2018 · Journal of Biological Chemistry
  90. Effect of Obstructive Sleep Apnea on Cardiovascular Function in Obese Youth
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  91. Causative Mechanisms of Childhood and Adolescent Obesity Leading to Adult Cardiometabolic Disease: A Literature Review
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  92. Adiponectin inhibits oxidized low density lipoprotein-induced increase in matrix metalloproteinase 9 expression in vascular smooth muscle cells.
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  93. Leptin Expression in Dogs with Cardiac Disease and Congestive Heart Failure
    Sonja Fonfara, Udo Hetzel, Simon R. Tew, Joanna Dukes‐McEwan, Peter Cripps, Peter Clegg · 2011 · Journal of Veterinary Internal Medicine
  94. Evaluation of left ventricular rotation in obese subjects by velocity vector imaging
    Yan Deng, Mohammed Saad AlHarthi, Venkata R Thota, Lixue Yin, Chunling Li, Usha R Emani, Krishnaswamy Chandrasekaran, Bijoy K. Khandheria, Farouk Mookadam · 2010 · European Journal of Echocardiography
  95. Body Habitus in Heart Failure: Understanding the Mechanisms and Clinical Significance of the Obesity Paradox
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  96. Maternal obesity in the ewe increases cardiac ventricular expression of glucocorticoid receptors, proinflammatory cytokines and fibrosis in adult male offspring
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  97. No Obesity Paradox in Pediatric Patients With Dilated Cardiomyopathy
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  98. Plasma antioxidants and oxidative stress status in obese women: correlation with cardiopulmonary response
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  99. Glucagon‐like peptide‐1 receptor agonist treatment of high carbohydrate intake‐induced metabolic syndrome provides pleiotropic effects on cardiac dysfunction through alleviations in electrical and intracellular Ca2+ abnormalities and mitochondrial dysfunction
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  100. The Impact of Bariatric Surgery on Cardiac Structure, and Systolic and Diastolic Function in Patients with Obesity: A Systematic Review and Meta-analysis
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