Transmembrane transport of endo- and xenobiotics by mammalian ATP-binding cassette multidrug resistance proteins

Deeley, Roger G., Westlake, Christopher, Cole, Susan P. C.·2006·Physiological Reviews
DOI 10.1152/physrev.00035.2005

Cites (584)

Items 201–400 of 584

  1. Regulation by glutathione of drug transport in multidrug-resistant human lung tumour cell lines overexpressing multidrug resistance-associated protein
    Carolien H.M. Versantvoort, Henk J. Broxterman, Tanya Bagrij, Rik J. Scheper, Peter R. Twentyman · 1995 · British Journal of Cancer
  2. Interaction of tyrosine kinase inhibitors with the human multidrug transporter proteins, MDR1 and MRP1
    Tamás Hegedűs, László Őrfi, Attila Seprődi, András Váradi, Balázs Sarkadi, Gÿorgý Kéri · 2002 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
  3. Major photoaffinity drug labeling sites for iodoaryl azidoprazosin in P-glycoprotein are within, or immediately C-terminal to, transmembrane domains 6 and 12
    Lee M. Greenberger · 1993 · Journal of Biological Chemistry
  4. The Transporter Associated With Antigen Processing: Function and Implications in Human Diseases
    Brigitte Lankat–Buttgereit, Robert Tampé · 2002 · Physiological Reviews
  5. Cyclosporins as drug resistance modifiers
    Peter R. Twentyman · 1992 · Biochemical Pharmacology
  6. Multidrug Resistance Protein 1 Protects the Oropharyngeal Mucosal Layer and the Testicular Tubules against Drug-induced Damage
    Jan Wijnholds, George L. Scheffer, Martin van der Valk, Paul van der Valk, Jos H. Beijnen, Rik J. Scheper, Piet Borst · 1998 · The Journal of Experimental Medicine
  7. A Spectrum of ABCC6 Mutations Is Responsible for Pseudoxanthoma Elasticum
    Olivier Le Saux, Konstanze Beck, Christine Sachsinger, Chiara Silvestri, Carina Treiber, Harald H.H. Göring, Eric W. Johnson, Anne De Paepe, Francis Michael Pope, Ivonne Pasquali‐Ronchetti et al. · 2001 · The American Journal of Human Genetics
  8. pABC11 (Also Known as MOAT-C and MRP5), a Member of the ABC Family of Proteins, Has Anion Transporter Activity but Does Not Confer Multidrug Resistance When Overexpressed in Human Embryonic Kidney 293 Cells
    Marcia A. McAleer, Maria A. Breen, Nina L. White · 1999 · Journal of Biological Chemistry
  9. Analysis of the Drug Resistance Profile of Multidrug Resistance Protein 7 (ABCC10)
    Elizabeth A. Hopper-Borge, Zhe‐Sheng Chen, Irina Shchaveleva, Martin G. Belinsky, Gary D. Kruh · 2004 · Cancer Research
  10. Detection of the M(r) 190,000 multidrug resistance protein, MRP, with monoclonal antibodies.
    David R. Hipfner, Stephan D. Gauldie, Roger G. Deeley · 1994 · PubMed
  11. ATP-Dependent Transport of Aflatoxin B1 and Its Glutathione Conjugates by the Product of the Multidrug Resistance Protein (MRP) Gene
    Douglas W. Loe, Richard K. Stewart, Thomas E. Massey, Roger G. Deeley, Susan P.C. Cole · 1997 · Molecular Pharmacology
  12. Expression and localization of human multidrug resistance protein (ABCC) family members in pancreatic carcinoma
    Jörg König, Mark Hartel, Anne T. Nies · 2005 · International Journal of Cancer
  13. Three-dimensional Structures of the Mammalian Multidrug Resistance P-glycoprotein Demonstrate Major Conformational Changes in the Transmembrane Domains upon Nucleotide Binding
    Mark F. Rosenberg, Alhaji Bukar Kamis, Richard Callaghan, Christopher F. Higgins, Robert C. Ford · 2003 · Journal of Biological Chemistry
  14. Function and Expression of Multidrug Resistance-Associated Protein Family in Human Colon Adenocarcinoma Cells (Caco-2)
    Tomoko Hirohashi, Hiroshi Suzuki, Xiaoyan Chu, Ikumi Tamai, Akira Tsuji, Yuichi Sugiyama · 2000 · Journal of Pharmacology and Experimental Therapeutics
  15. Membrane Insertion of a Potassium-Channel Voltage Sensor
    Tara Hessa, Stephen H. White, Gunnar von HEIJNE · 2005 · Science
  16. Subcellular Localization and Activity of Multidrug Resistance Proteins
    Asha Rajagopal, Sanford M. Simon · 2003 · Molecular Biology of the Cell
  17. Role of MRP2 and GSH in intrahepatic cycling of toxins
    Ch F Dietrich · 2001 · Toxicology
  18. Expression of the multidrug resistance proteins MRP2 and MRP3 in human hepatocellular carcinoma
    Anne T. Nies, Jörg König, Marion Pfannschmidt, Ernst Klar, Walter J Hofmann, Dietrich O. R. KEPPLER · 2001 · International Journal of Cancer
  19. Characterization of bile acid transport mediated by multidrug resistance associated protein 2 and bile salt export pump
    Hidetaka Akita, Hiroshi Suzuki, Kousei Ito, Setsuo Kinoshita, Norihito Sato, Hajime Takikawa, Yuichi Sugiyama · 2001 · Biochimica et Biophysica Acta (BBA) - Biomembranes
  20. Transport of monoglucuronosyl and bisglucuronosyl bilirubin by recombinant human and rat multidrug resistance protein 2
    Toshinori Kamisako, Inka Leier, Yunhai Cui, Jörg König, Ulrike Buchholz, Johanna Hummel-Eisenbeiss, Dietrich O. R. KEPPLER · 1999 · Hepatology
  21. Site-Directed Fluorescence Labeling of P-Glycoprotein on Cysteine Residues in the Nucleotide Binding Domains
    Ronghua Liu, Frances Jane Sharom · 1996 · Biochemistry
  22. Crystal Structure of the Nucleotide-binding Domain of the ABC-transporter Haemolysin B: Identification of a Variable Region Within ABC Helical Domains
    Lutz Schmitt, Houssain Benabdelhak, Mark A. Blight, Ian Barry Holland, Milton T. Stubbs · 2003 · Journal of Molecular Biology
  23. Increased expression of an ATP-binding cassette superfamily transporter, multidrug resistance protein 2, in human colorectal carcinomas.
    Eiji Hinoshita, Takeshi Uchiumi, K Taguchi, Naoko Kinukawa, Masazumi Tsuneyoshi, Yoshihiko Maehara, Keizō Sugimachi, Michihiko Kuwano · 2000 · PubMed
  24. Simultaneous Activity of MRP1 and Pgp Is Correlated With In Vitro Resistance to Daunorubicin and With In Vivo Resistance in Adult Acute Myeloid Leukemia
    Ollivier Legrand, Ghislaine Simonin, Anne Beauchamp‐Nicoud, R Zittoun, Jean‐Pierre Marie · 1999 · Blood
  25. Effect of Multidrug Resistance-Reversing Agents on Transporting Activity of Human Canalicular Multispecific Organic Anion Transporter
    Zhe‐Sheng Chen, Takeshi Kawabe, Mayumi Ono, Shunji Aoki, Tomoyuki Sumizawa, Tatsuhiko Furukawa, Takeshi Uchiumi, Morimasa Wada, Michihiko Kuwano, Shin-ichi Akiyama · 1999 · Molecular Pharmacology
  26. Analysis of the structure and expression pattern of MRP7 (ABCC10), a new member of the MRP subfamily
    Elizabeth A. Hopper-Borge, Martin G. Belinsky, Hao Zeng, Alessandra Tosolini, Joseph R. Testa, Gary D. Kruh · 2001 · Cancer Letters
  27. Plasma Membrane Localization of Multidrug Resistance-Associated Protein Homologs in Brain Capillary Endothelial Cells
    Yan Zhang, John D. Schuetz, William F. Elmquist, Donald W. Miller · 2004 · Journal of Pharmacology and Experimental Therapeutics
  28. N‐terminal transmembrane domain of the SUR controls trafficking and gating of Kir6 channel subunits
    Kim W. Chan, Hailin Zhang, Diomedes E. Logothetis · 2003 · The EMBO Journal
  29. Comparison of the Functional Characteristics of the Nucleotide Binding Domains of Multidrug Resistance Protein 1
    Mian Gao, Heng-Ran Cui, Douglas W. Loe, Caroline E. Grant, Kurt C. Almquist, Susan P.C. Cole, Roger G. Deeley · 2000 · Journal of Biological Chemistry
  30. Multidrug resistance-associated protein 4 is up-regulated in liver but down-regulated in kidney in obstructive cholestasis in the rat
    Gerald Denk, Carol J. Soroka, Yasuaki Takeyama, Wensheng Chen, John D. Schuetz, James Lorenzen Boyer · 2003 · Journal of Hepatology
  31. MRP8, A New Member of ABC Transporter Superfamily, Identified by EST Database Mining and Gene Prediction Program, Is Highly Expressed in Breast Cancer
    Tapan Kumar Bera, Sang Hyuk Lee, Giuliana Salvatore · 2001 · Molecular Medicine
  32. Determining the Dimensions of the Drug-binding Domain of Human P-glycoprotein Using Thiol Cross-linking Compounds as Molecular Rulers
    Tip W. Loo, David M. Clarke · 2001 · Journal of Biological Chemistry
  33. Function, evolution and structure of multidrug resistance protein (MRP)
    Roger G. Deeley, Susan P.C. Cole · 1997 · Seminars in Cancer Biology
  34. Expression of the multidrug resistance-associated protein (MRP) gene in human cancers.
    Kees Nooter, Anne Marie Westerman, Marcel J. Flens, G J Zaman, Rik J. Scheper, Kyra E. van Wingerden, Henry Burger, Robert G. Oostrum, Ton Boersma, Pieter Sonneveld · 1995 · PubMed
  35. Cellular Export of Drugs and Signaling Molecules by the ATP-binding Cassette Transporters MRP4 (ABCC4) and MRP5 (ABCC5)
    Christoph Alexander Ritter, Gabriele Jedlitschky, Henriette E. Meyer zu Schwabedissen, Markus Grube, Kathleen Köck, Heyo K. Kroemer · 2005 · Drug Metabolism Reviews
  36. PERSISTENT NONHEMOLYTIC HYPERBILIRUBINEMIA ASSOCIATED WITH LIPOCHROMELIKE PIGMENT IN LIVER CELLS: REPORT OF FOUR CASES
    Helmuth Sprinz, ROBERT S. NELSON · 1954 · Annals of Internal Medicine
  37. Expression of multidrug resistance protein-3 (multispecific organic anion transporter-D) in human embryonic kidney 293 cells confers resistance to anticancer agents.
    Hao Zeng, Lisa J. Bain, Martin G. Belinsky, Gary D. Kruh · 1999 · PubMed
  38. Structure-function analysis of the histidine permease and comparison with cystic fibrosis mutations.
    Venkatakrishna Shyamala, V. Baichwal, Eileen L. Beall, Giovanna Ferro-Luzzi Ames · 1991 · Journal of Biological Chemistry
  39. MgADP Antagonism to Mg2+-independent ATP Binding of the Sulfonylurea Receptor SUR1
    Kazumitsu Ueda, Nobuya Inagaki, Susumu Seino · 1997 · Journal of Biological Chemistry
  40. Potential role of ABC transporters as a detoxification system at the blood?CSF barrier
    E DELANGE · 2004 · Advanced Drug Delivery Reviews
  41. Non-P-glycoprotein-mediated multidrug resistance in a small cell lung cancer cell line: Evidence for decreased susceptibility to drug-induced DNA damage and reduced levels of topoisomerase II
    Susan P.C. Cole · 1992 · Lung Cancer
  42. MRP Subfamily Transporters and Resistance to Anticancer Agents
    Gary D. Kruh, Hao Zeng, Philip A. Rea, Guosheng Liu, Zhe‐Sheng Chen, Kun Hee Lee, Martin G. Belinsky · 2001 · Journal of Bioenergetics and Biomembranes
  43. Characterization of MOAT-C and MOAT-D, New Members of the MRP/cMOAT Subfamily of Transporter Proteins
    Martin G. Belinsky, Lisa J. Bain, Binaifer Balsara, Joseph R. Testa, Gary D. Kruh · 1998 · JNCI Journal of the National Cancer Institute
  44. VX-710 (Biricodar) Increases Drug Retention and Enhances Chemosensitivity in Resistant Cells Overexpressing P-Glycoprotein, Multidrug Resistance Protein, and Breast Cancer Resistance Protein
    Hans Minderman, Kieran L. O’Loughlin, Lakshmi Pendyala, Maria R. Baer · 2004 · Clinical Cancer Research
  45. Structural analysis of cloned plasma membrane proteins by freeze-fracture electron microscopy
    Sepehr Eskandari, Ernest Marshall Wright, Mike Kreman, Dorine M. Starace, Guido A. Zampighi · 1998 · Proceedings of the National Academy of Sciences
  46. Changes in the expression and localization of hepatocellular transporters and radixin in primary biliary cirrhosis
    Hideyuki Kojima, Anne T. Nies, Jörg König · 2003 · Journal of Hepatology
  47. Transport of the β-O-Glucuronide Conjugate of the Tobacco-specific Carcinogen 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) by the Multidrug Resistance Protein 1 (MRP1)
    Elaine M. Leslie, Ken-ichi Ito, Pramod Upadhyaya, Stephen S. Hecht, Roger G. Deeley, Susan P.C. Cole · 2001 · Journal of Biological Chemistry
  48. Analysis of the In Vivo Functions of Mrp3
    Martin G. Belinsky, Paul A Dawson, Irina Shchaveleva, Lisa J. Bain, Renxue Wang, Victor Wei Teik Ling, Zhe‐Sheng Chen, Alex Grinberg, Heiner Westphal, Andres J. Klein–Szanto et al. · 2005 · Molecular Pharmacology
  49. Mutation of a Single Conserved Tryptophan in Multidrug Resistance Protein 1 (MRP1/ABCC1) Results in Loss of Drug Resistance and Selective Loss of Organic Anion Transport
    Ken‐ichi Ito, Sharon L. Olsen, Wei Qiu, Roger G. Deeley, Susan P.C. Cole · 2001 · Journal of Biological Chemistry
  50. Expression and localization of the multidrug resistance-associated protein 3 in rat small and large intestine
    Daniel Rost, Sven Mahner, Yuichi Sugiyama · 2002 · American Journal of Physiology-Gastrointestinal and Liver Physiology
  51. Glutathione Stimulates Sulfated Estrogen Transport by Multidrug Resistance Protein 1
    Yueming Qian, Wen‐Chao Song, Heng-Ran Cui, Susan P.C. Cole, Roger G. Deeley · 2001 · Journal of Biological Chemistry
  52. Clinical Studies with Modulators of Multidrug Resistance
    George Albert Fisher, Branimir Ivan Sikic · 1995 · Hematology/Oncology Clinics of North America
  53. Three-dimensional Structure of P-glycoprotein
    Mark F. Rosenberg, Richard Callaghan, Szabolcs Modok · 2004 · Journal of Biological Chemistry
  54. The Structure of the Multidrug Resistance Protein 1 (MRP1/ABCC1)
    Mark F. Rosenberg, Qingcheng Mao, Andreas Holzenburg, Robert C. Ford, Roger G. Deeley, Susan P.C. Cole · 2001 · Journal of Biological Chemistry
  55. Crystal Structures of the ATPase Subunit of the Glucose ABC Transporter from Sulfolobus solfataricus: Nucleotide-free and Nucleotide-bound Conformations
    Grégory Verdon, Sonja‐Verena Albers, Bauke W. Dijkstra, Arnold J. M. Driessen, A.M.W.H. Thunnissen · 2003 · Journal of Molecular Biology
  56. Characterization of the Transport Properties of Human Multidrug Resistance Protein 7 (MRP7, ABCC10)
    Zhe‐Sheng Chen, Elizabeth A. Hopper-Borge, Martin G. Belinsky, Irina Shchaveleva, Elena Kotova, Gary D. Kruh · 2003 · Molecular Pharmacology
  57. Prolonged Nonhydrolytic Interaction of Nucleotide with CFTR's NH2-terminal Nucleotide Binding Domain and its Role in Channel Gating
    Claudia Basso, Paola Vergani, Angus C. Nairn · 2003 · The Journal of General Physiology
  58. Verapamil Stimulates Glutathione Transport by the 190-kDa Multidrug Resistance Protein 1 (MRP1)
    Douglas W. Loe, Roger G. Deeley, Susan P.C. Cole · 2000 · Journal of Pharmacology and Experimental Therapeutics
  59. Enhanced transport of anticancer agents and leukotriene C4 by the human canalicular multispecific organic anion transporter (cMOAT/MRP2)
    Takeshi Kawabe, Zhe‐Sheng Chen, Morimasa Wada · 1999 · FEBS Letters
  60. Reconstitution of ATP-dependent Leukotriene C4 Transport by Co-expression of Both Half-molecules of Human Multidrug Resistance Protein in Insect Cells
    Mian Gao, Douglas W. Loe, Caroline E. Grant, Susan P.C. Cole, Roger G. Deeley · 1996 · Journal of Biological Chemistry
  61. The multidrug resistance protein MRP1 mediates the release of glutathione disulfide from rat astrocytes during oxidative stress
    Hirrlinger, Johannes, König, Jörg, Keppler, Dietrich, Lindenau, Jörg, Schulz, Jörg B., Dringen, Ralf · 2001 · Journal of Neurochemistry
  62. Characterization of the ATP‐dependent leukotriene C4 export carrier in mastocytoma cells
    Inka Leier, Gabriele Jedlitschky, Ulrike Buchholz, Dietrich O. R. KEPPLER · 1994 · European Journal of Biochemistry
  63. A point mutation inactivating the sulfonylurea receptor causes the severe form of persistent hyperinsulinemic hypoglycemia of infancy in Finland.
    Timo Otonkoski, Carina Ämmälä, Hanna Huopio, Gilbert J. Cote, JC Chapman, Karen E. Cosgrove, Rebecca Ashfield, Elbert S. Huang, Jorma Komulainen, Frances M. Ashcroft et al. · 1999 · Diabetes
  64. Characterization of the Catalytic Cycle of ATP Hydrolysis by Human P-glycoprotein
    Zuben E. Sauna, Suresh V. Ambudkar · 2001 · Journal of Biological Chemistry
  65. The prognostic significance of expression of the multidrug resistance-associated protein (MRP) in primary breast cancer
    Kees Nooter, Guy Brutel de la Rivière, Maxime P. Look, Kyra E. van Wingerden, Sonja C. Henzen-Logmans, Rik J. Scheper, Marcel J. Flens, J.G.M. Klijn, G. Stoter, John A. Foekens · 1997 · British Journal of Cancer
  66. Clinical prognostic factors in 1277 patients with neuroblastoma: results of The European Neuroblastoma Study Group ‘Survey’ 1982–1992
    Simon J. Cotterill, A. D. J. Pearson, Jon Pritchard · 2000 · European Journal of Cancer
  67. Mechanism of ABC transporters: A molecular dynamics simulation of a well characterized nucleotide-binding subunit
    Peter M. Jones, Anthony M. George · 2002 · Proceedings of the National Academy of Sciences
  68. Bilirubin protects astrocytes from its own toxicity by inducing up-regulation and translocation of multidrug resistance-associated protein 1 (Mrp1)
    Florinda Gennuso, Cristina Fernetti, Cataldo Tirolo, Nunzio Testa, Francesca L’Episcopo, Salvatore Caniglia, Maria C. Morale, J. Donald Ostrow, Lorella Pascolo, Claudio Tiribelli et al. · 2004 · Proceedings of the National Academy of Sciences
  69. A Phase I Trial of a Potent P-Glycoprotein Inhibitor, Zosuquidar Trihydrochloride (LY335979), Administered Intravenously in Combination with Doxorubicin in Patients with Advanced Malignancy
    Alan B. Sandler, Michael S. Gordon, Dinesh P. de Alwis, Isabelle J. Pouliquen, Lisa Green, Phil Marder, Ajai Kumar Chaudhary, Karen Fife, Linda A. Battiato, Christopher J. Sweeney et al. · 2004 · Clinical Cancer Research
  70. Localization of a novel multidrug resistance-associated gene in the HT1080/DR4 and H69AR human tumor cell lines.
    Marilyn L. Slovak, Jennifer Pelkey Ho, Gabu Bhardwaj, Ebba U. Kurz, Roger G. Deeley, Susan P.C. Cole · 1993 · PubMed
  71. Isolation of MOAT-B, a widely expressed multidrug resistance-associated protein/canalicular multispecific organic anion transporter-related transporter.
    K Lee, Martin G. Belinsky, Daphne W. Bell, Joseph R. Testa, Gary D. Kruh · 1998 · PubMed
  72. SUR Domains That Associate with and Gate KATP Pores Define a Novel Gatekeeper
    Andrey P. Babenko, Joseph Bryan · 2003 · Journal of Biological Chemistry
  73. A new multidrug resistance protein at the blood–brain barrier
    Tanja Eisenblätter, Hans‐Joachim Galla · 2002 · Biochemical and Biophysical Research Communications
  74. Anticancer multidrug resistance mediated by MRP1: Recent advances in the discovery of reversal agents
    Ahcène Boumendjel, Hélène Baubichon-Cortay, Doriane Trompier, Thomas Perrotton, Attilio Di Pietro · 2005 · Medicinal Research Reviews
  75. Transgenic mice that express the human multidrug-resistance gene in bone marrow enable a rapid identification of agents that reverse drug resistance.
    G. Mickisch, Glenn T Merlino, Hanan Galski · 1991 · Proceedings of the National Academy of Sciences
  76. Contribution of Multidrug Resistance Protein 2 (MRP2/ABCC2) to the Renal Excretion of p-aminohippurate (PAH) and Identification of MRP4 (ABCC4) as a Novel PAH Transporter
    Pascal H. E. Smeets, Re[Combining Acute Accent]mon A.M.H. van Aubel, Alfons C. Wouterse · 2004 · Journal of the American Society of Nephrology
  77. Characterization of the M(r) 190,000 multidrug resistance protein (MRP) in drug-selected and transfected human tumor cell.
    Kurt C. Almquist, Douglas W. Loe, David R. Hipfner, Jane E. Mackie, Susan P.C. Cole, Roger G. Deeley · 1995 · PubMed
  78. Two new genes from the human ATP-binding cassette transporter superfamily, ABCC11 and ABCC12, tandemly duplicated on chromosome 16q12
    Jaana Tammur, Catherine Prades, Isabelle Reguigne-Arnould, Andrey Rzhetsky, Amy A Hutchinson, Masashi Adachi, John D. Schuetz, Kathryn J. Swoboda, Louis J. Ptáček, Marie Rosier et al. · 2001 · Gene
  79. Role of glutathione in the multidrug resistance protein 4 (MRP4/ABCC4)-mediated efflux of cAMP and resistance to purine analogues
    Liqi LAI, Theresa May Chin Tan · 2002 · Biochemical Journal
  80. Different Binding Properties and Affinities for ATP and ADP among Sulfonylurea Receptor Subtypes, SUR1, SUR2A, and SUR2B
    Michinori Matsuo, Kouichi Tanabe, Noriyuki Kioka, Teruo Amachi, Kazumitsu Ueda · 2000 · Journal of Biological Chemistry
  81. Localization and Suppression of a Kinetic Defect in Cystic Fibrosis Transmembrane Conductance Regulator Folding
    Bao-He Qu, Elizabeth Strickland, Philip Thomas · 1997 · Journal of Biological Chemistry
  82. Pharmacological Characterization of the Murine and Human Orthologs of Multidrug-Resistance Protein in Transfected Human Embryonic Kidney Cells
    Brenda D. Stride, Caroline E. Grant, Douglas W. Loe, David R. Hipfner, Susan P.C. Cole, Roger G. Deeley · 1997 · Molecular Pharmacology
  83. The “LSGGQ” Motif in Each Nucleotide-binding Domain of Human P-glycoprotein Is Adjacent to the Opposing Walker A Sequence
    Tip W. Loo, M. Claire Bartlett, David M. Clarke · 2002 · Journal of Biological Chemistry
  84. Substrate recognition by P-glycoprotein and the multidrug resistance-associated protein MRP1: a comparison
    Anna Seelig, Xiaochun Li Blatter, Frank Wohnsland · 2000 · International Journal of Clinical Pharmacology and Therapeutics
  85. MOAT-E (ARA) is a full-length MRP/cMOAT subfamily transporter expressed in kidney and liver
    Martin G. Belinsky, Gary D. Kruh · 1999 · British Journal of Cancer
  86. Purification and Crystallization of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR)
    Mark F. Rosenberg, Alhaji Bukar Kamis, Luba A. Aleksandrov · 2004 · Journal of Biological Chemistry
  87. Multidrug resistance markers P-glycoprotein, multidrug resistance protein 1, and lung resistance protein in non-small cell lung cancer: prognostic implications
    Walter Berger, Ulrike Setinek, Peter H. Hollaus, Thomas Zidek, Elisabeth Steiner, Leonilla Elbling, Heidelinde Cantonati, Johannes Attems, Andrea Gsur, M. Micksche · 2005 · Journal of Cancer Research and Clinical Oncology
  88. Increased levels of the multidrug resistance protein in lateral membranes of proliferating hepatocyte-derived cells
    Han Roelofsen, Thera A. Vos, I.J. Schippers, Folkert Kuipers, Hans Koning, Han J. Moshage, Peter L. M. Jansen, Michael M. Müller · 1997 · Gastroenterology
  89. The Human Multidrug Resistance Protein MRP5 Transports Folates and Can Mediate Cellular Resistance against Antifolates
    Peter R. Wielinga, Jan Hendrik Hooijberg, Sjöfn Gunnarsdottir, Ietje Kathmann, Glen Reid, Noam Zelcer, Kasper van der Born, Marcel de Haas, Ingrid van der Heijden, Gertjan J.L. Kaspers et al. · 2005 · Cancer Research
  90. ATPase Activity of Purified Multidrug Resistance-associated Protein
    Xiu-Bao Chang, Yue-xian Hou, John R. Riordan · 1997 · Journal of Biological Chemistry
  91. The C Terminus of SUR1 Is Required for Trafficking of KATP Channels
    Nidhi Sharma, Ana Crane, John P. Clement, Gabriela González, Andrey P. Babenko, Joseph Bryan, Lydia Aguilar‐Bryan · 1999 · Journal of Biological Chemistry
  92. Modulation of P‐glycoprotein but not MRP1‐ or BCRP‐mediated drug resistance by LY335979
    Robert L. Shepard, Jin Cao, James J. Starling, Anne H. Dantzig · 2002 · International Journal of Cancer
  93. Transport of glutathione prostaglandin A conjugates by the multidrug resistance protein 1
    Raymond Evers, Nicole H.P. Cnubben, Jan Wijnholds, Liesbeth van Deemter, Peter J. van BLADEREN, Piet Borst · 1997 · FEBS Letters
  94. PDZK1, a novel PDZ domain-containing protein up-regulated in carcinomas and mapped to chromosome 1q21, interacts with cMOAT (MRP2), the multidrug resistance-associated protein.
    Olivier N. Kocher, Natalia Comella, Annalyn Gilchrist, Rinku Pal, Kathi Tognazzi, L F Brown, Joan H.M. Knoll · 1999 · PubMed
  95. Allosteric Interactions between the Two Non-equivalent Nucleotide Binding Domains of Multidrug Resistance Protein MRP1
    Yue-xian Hou, Liying Cui, John R. Riordan, Xiu-Bao Chang · 2000 · Journal of Biological Chemistry
  96. Tissue and Cell Distribution of the Multidrug Resistance-Associated Protein (MRP) in Mouse Intestine and Kidney
    Kou‐Cheng Peng, Françoise Cluzeaud, Marcelle Bens, Jean–Paul Duong Van Huyen, My-Anh Wioland, Roger Lacave, Alain Vandewalle · 1999 · Journal of Histochemistry & Cytochemistry
  97. Pharmacological considerations in the modulation of multidrug resistance
    George Albert Fisher, B L Lum, John Hausdorff · 1996 · European Journal of Cancer
  98. Expression of multidrug transporterMRP4/ABCC4is a marker of poor prognosis in neuroblastoma and confers resistance to irinotecanin vitro
    Murray D. Norris, Janice L. Smith, Kara M. Tanabe, Peter J. Tobin, Claudia L. Flemming, George L. Scheffer, Peter R. Wielinga, Susan Lerner Cohn, Wendy B. London, Glenn M. Marshall et al. · 2005 · Molecular Cancer Therapeutics
  99. Transport of Bile Acids, Sulfated Steroids, Estradiol 17-β-d-Glucuronide, and Leukotriene C4 by Human Multidrug Resistance Protein 8 (ABCC11)
    Zhe‐Sheng Chen, Yanping Guo, Martin G. Belinsky, Elena Kotova, Gary D. Kruh · 2004 · Molecular Pharmacology
  100. Multidrug resistance protein attenuates gemtuzumab ozogamicin–induced cytotoxicity in acute myeloid leukemia cells
    Roland B. Walter, Brian W. Raden, Tom C. Hong · 2003 · Blood
  101. ABC1, an ATP Binding Cassette Transporter Required for Phagocytosis of Apoptotic Cells, Generates a Regulated Anion Flux after Expression in Xenopus laevis Oocytes
    Frédéric Becq, Yannick Hamon, Adriana Bajetto, Maurice Gola, Bernard Verrier, Giovanna Chimini · 1997 · Journal of Biological Chemistry
  102. Expression of mRNAs of multidrug resistance proteins (Mrps) in cultured rat astrocytes, oligodendrocytes, microglial cells and neurones
    Johannes Hirrlinger, Jörg König, Ralf Dringen · 2002 · Journal of Neurochemistry
  103. Mutation of Trp1254 in the Multispecific Organic Anion Transporter, Multidrug Resistance Protein 2 (MRP2) (ABCC2), Alters Substrate Specificity and Results in Loss of Methotrexate Transport Activity
    Ken‐ichi Ito, Curtis J. Oleschuk, Chris Westlake, Monika Z. Vasa, Roger G. Deeley, Susan P.C. Cole · 2001 · Journal of Biological Chemistry
  104. Cross-resistance to diverse drugs is associated with primary cisplatin resistance in ovarian cancer cell lines.
    K Hamaguchi, Andrew K. Godwin, MICHIAKI YAKUSHIJI · 1993 · PubMed
  105. Both ATP Sites of Human P-Glycoprotein Are Essential but Not Symmetric
    Christine A. Hrycyna, Murali Ramachandra, Ursula A. Germann · 1999 · Biochemistry
  106. Chemosensitization and drug accumulation effects of VX-710, verapamil, cyclosporin A, MS-209 and GF120918 in multidrug resistant HL60/ADR cells expressing the multidrug resistance-associated protein MRP
    Ursula A. Germann, Pamella J. Ford, Dina Shlyakhter, Valerie S. Mason, Matthew W. Harding · 1997 · Anti-Cancer Drugs
  107. Cellular and biochemical characterization of VX-710 as a chemosensitizer
    Ursula A. Germann, Dlna Shlyakhter, Valerie S. Mason · 1997 · Anti-Cancer Drugs
  108. ATP hydrolysis cycles and mechanism inP-glycoprotein and CFTR
    Alan E. Senior, David C. Gadsby · 1997 · Seminars in Cancer Biology
  109. Overexpression of cMOAT (MRP2/ABCC2) Is Associated with Decreased Formation of Platinum-DNA Adducts and Decreased G2-Arrest in Melanoma Cells Resistant to Cisplatin
    Bernd Liedert, Verena Materna, Dirk Schadendorf, Jürgen Thomale, Hermann Lage · 2003 · Journal of Investigative Dermatology
  110. The Multidrug Resistance-associated Protein (MRP) Subfamily (Yrs1/Yor1) of Is Important for the Tolerance to a Broad Range of Organic Anions
    Zhifeng Cui, Dai Hirata, Eiko Tsuchiya, Hiroyuki Osada, Tokichi Miyakawa · 1996 · Journal of Biological Chemistry
  111. Sulfonylurea receptors: ABC transporters that regulate ATP-sensitive K+ channels
    Joseph Bryan, Lydia Aguilar‐Bryan · 1999 · Biochimica et Biophysica Acta (BBA) - Biomembranes
  112. Transport Activity of Human MRP3 Expressed in Sf9 Cells: Comparative Studies with Rat MRP3
    Hidetaka Akita, Hiroshi Suzuki, Tomoko Hirohashi, Hajime Takikawa, Yuichi Sugiyama · 2002 · Pharmaceutical Research
  113. Intrinsic Fluorescence of the P-glycoprotein Multidrug Transporter: Sensitivity of Tryptophan Residues to Binding of Drugs and Nucleotides
    Ronghua Liu, Aleksander Siemiarczuk, Frances Jane Sharom · 2000 · Biochemistry
  114. Regulation of expression of the multidrug resistance protein MRP1 by p53 in human prostate cancer cells
    Gregory F. Sullivan, Jinming Yang, Andrew D. Vassil, Jun Yang, Judy Bash-Babula, William N. Hait · 2000 · Journal of Clinical Investigation
  115. Bioflavonoid Stimulation of Glutathione Transport by the 190-kDa Multidrug Resistance Protein 1 (MRP1)
    Elaine M. Leslie, Roger G. Deeley, Susan P.C. Cole · 2003 · Drug Metabolism and Disposition
  116. Molecular genetics of pseudoxanthoma elasticum: a metabolic disorder at the environment–genome interface?
    Jouni Uitto, Leena Pulkkinen, Franziska Ringpfeil · 2001 · Trends in Molecular Medicine
  117. ATP-dependent transport of glutathione S-conjugates by the multidrug resistance protein MRP1 and its apical isoform MRP2
    Dietrich O. R. KEPPLER, Inka Leier, Gabriele Jedlitschky, Jörg König · 1998 · Chemico-Biological Interactions
  118. MRP9, an unusual truncated member of the ABC transporter superfamily, is highly expressed in breast cancer
    Tapan Kumar Bera, Carlo Iavarone, Vasantha Kumar M.V. · 2002 · Proceedings of the National Academy of Sciences
  119. Expression of MRP4 Confers Resistance to Ganciclovir and Compromises Bystander Cell Killing
    Masashi Adachi, Janardhan Sampath, Lu-Bin Lan, Daxi Sun, Philip Hargrove, Robin M. Flatley, Ann Tatum, Mary Z. Edwards, Michele J. Wezeman, Larry H. Matherly et al. · 2002 · Journal of Biological Chemistry
  120. Basal Membrane Localization of MRP1 in Human Placental Trophoblast
    M. Nagashige, Fumihiko Ushigome, Noriko Koyabu, K. Hirata, Masaru Kawabuchi, T. Hirakawa, Shoji Satoh, Kiyomi Tsukimori, Hideki Nakano, Takeshi Uchiumi et al. · 2003 · Placenta
  121. Expression of multidrug resistance‐associated protein 2 (MRP2) in normal human tissues and carcinomas using tissue microarrays
    George Earl Sandusky, Karen Mintze, Susan E. Pratt, Anne H. Dantzig · 2002 · Histopathology
  122. Altered Hepatobiliary Disposition of Acetaminophen Glucuronide in Isolated Perfused Livers from Multidrug Resistance-Associated Protein 2-Deficient TR− Rats
    Hao Xiong, Kenneth C. Turner, E. Stacy Ward · 2000 · Journal of Pharmacology and Experimental Therapeutics
  123. Role of MDR1 and MRP1 in trophoblast cells, elucidated using retroviral gene transfer
    Diane E. Atkinson, Susan L. Greenwood, Colin Peter Sibley, Jocelyn D. Glazier, LJ Fairbairn · 2003 · American Journal of Physiology-Cell Physiology
  124. Multidrug resistance protein MRP1 protects against the toxicity of the major lipid peroxidation product 4-hydroxynonenal
    Johan Renes, Elisabeth G.E. de Vries, Guido J. E. J. Hooiveld, Inge KRIKKEN, Peter L. M. Jansen, Michael M. Müller · 2000 · Biochemical Journal
  125. Leukotrienes as Mediators of Asthma
    SIMONETTA NICOSIA, Valérie Capra, G. Enrico Rovati · 2001 · Pulmonary Pharmacology & Therapeutics
  126. Characterization of the amino-terminal regions in the human multidrug resistance protein (MRP1)
    Éva Bakos, Raymond Evers, Giulia Calenda, Gábor Tusnády, Gergely Szakács, András Váradi, Balázs Sarkadi · 2000 · Journal of Cell Science
  127. Biliary and Urinary Excretion of Inorganic Arsenic: Monomethylarsonous Acid as a Major Biliary Metabolite in Rats
    Zoltán Gregus · 2000 · Toxicological Sciences
  128. An atomic detail model for the human ATP binding cassette transporter P‐glycoprotein derived from disulphide cross‐ linking and homology modeling
    Daniella R. Stenham, Jeff D. Campbell, Mark S.P. Sansom, Christopher F. Higgins, Ian Derek Kerr, Kenneth J. Linton · 2003 · The FASEB Journal
  129. Conversion of leukotriene D4 to leukotriene E4 by a dipeptidase released from the specific granule of human polymorphonuclear leucocytes.
    C W Lee, R A Lewis, E.J. Corey · 1983 · PubMed
  130. Transcriptional suppression of multidrug resistance-associated protein (MRP) gene expression by wild-type p53.
    Q Wang, William T. Beck · 1998 · PubMed
  131. The canalicular multispecific organic anion transporter and conjugated hyperbilirubinemia in rat and man
    Coen C. Paulusma, Ronald P.J. Oude Elferink · 1997 · Journal of Molecular Medicine
  132. Drug Binding in Human P-glycoprotein Causes Conformational Changes in Both Nucleotide-binding Domains
    Tip W. Loo, M. Claire Bartlett, David M. Clarke · 2003 · Journal of Biological Chemistry
  133. Structure and expression of the messenger RNA encoding the murine multidrug resistance protein, an ATP-binding cassette transporter.
    Brenda D. Stride, Gunnar Valdimarsson, James H. Gerlach · 1996 · Molecular Pharmacology
  134. Topology Mapping of the Amino-terminal Half of Multidrug Resistance-associated Protein by Epitope Insertion and Immunofluorescence
    Christina Kast, Philippe Gros · 1997 · Journal of Biological Chemistry
  135. Increased expression of multidrug resistance‐associated proteins in bladder cancer during clinical course and drug resistance to doxorubicin
    Yasuhiro Tada, Morimasa Wada, Toshiro Migita, Jun Nagayama, Eiji Hinoshita, Yasushi Mochida, Yoshihiko Maehara, Masazumi Tsuneyoshi, Michihiko Kuwano, Seiji Naito · 2002 · International Journal of Cancer
  136. Probenecid reverses multidrug resistance in multidrug resistance-associated protein-overexpressing HL60/AR and H69/AR cells but not in P-glycoprotein-overexpressing HL60/Tax and P388/ADR cells
    S Gollapudi, Choong Hyun Kim, Bich-Ngoc Tran, Soni Sangha, Sudhir Gupta · 1997 · Cancer Chemotherapy and Pharmacology
  137. The expression of drug resistance gene products during the progression of human prostate cancer.
    G F Sullivan, Peter Sebastian Amenta, J D Villanueva, Carmelita J. Alvarez, Jinming Yang, William N. Hait · 1998 · PubMed
  138. A naturally occurring mutation in MRP1 results in a selective decrease in organic anion transport and in increased doxorubicin resistance
    Silke Conrad, Hans-Martin Kauffmann, Ken‐ichi Ito, Elaine M. Leslie, Roger G. Deeley, Dieter Schrenk, Susan P.C. Cole · 2002 · Pharmacogenetics
  139. Location of a protease-hypersensitive region in the multidrug resistance protein (MRP) by mapping of the epitope of MRP-specific monoclonal antibody QCRL-1.
    David R. Hipfner, Kurt C. Almquist, Brenda D. Stride, R G Deeley, Susan P.C. Cole · 1996 · PubMed
  140. Competitive inhibition by genistein and ATP dependence of daunorubicin transport in intact MRP overexpressing human small cell lung cancer cells
    Carolien H.M. Versantvoort, Henk J. Broxterman, Jan Lankelma, N Feller, Herbert M. Pinedo · 1994 · Biochemical Pharmacology
  141. Mechanism of Coupling of Transport to Hydrolysis in Bacterial ATP-Binding Cassette Transporters
    Amy L. Davidson · 2002 · Journal of Bacteriology
  142. Effect of calcium antagonists on the chemosensitivity of two multidrug-resistant human tumour cell lines which do not overexpress P-glycoprotein
    SPC Cole, HF Downes, ML Slovak · 1989 · British Journal of Cancer
  143. Clinical Role of Multidrug Resistance Protein 1 Expression in Chemotherapy Resistance in Early-Stage Breast Cancer: The Austrian Breast and Colorectal Cancer Study Group
    Martin Filipits, Gudrun Pohl, Margaretha Rudas, Otto Dietze, Sigurd Lax, Renate Grill, Robert Pirker, Christoph Carl Zielinski, Hubert Hausmaninger, Ernst Kubista et al. · 2005 · Journal of Clinical Oncology
  144. Multiple Splicing Variants of Two New Human ATP-Binding Cassette Transporters, ABCC11 and ABCC12
    Hikaru Yabuuchi, Hidetada Shimizu, Shin‐ichiro Takayanagi, Toshihisa Ishikawa · 2001 · Biochemical and Biophysical Research Communications
  145. Expression of the multidrug resistance-associated protein (MRP) gene in non-small-cell lung cancer
    Eiichiro Ota, Yoshiyuki Abe, Yoshiro Oshika, Yuichi Ozeki, Masayuki Iwasaki, H Inoue, Hiroya Yamazaki, Yoshito Ueyama, Koichi Takagi, T Ogata et al. · 1995 · British Journal of Cancer
  146. Altered Disposition of Acetaminophen in Mice With a Disruption of the Mrp3 Gene * #
    José Enrique Manautou, Dirk Rudi de Waart, Cindy Kunne, Noam Zelcer, Michael J. Goedken, Piet Borst, Ronald P.J. Oude Elferink · 2005 · Hepatology
  147. Transport of Ethinylestradiol Glucuronide and Ethinylestradiol Sulfate by the Multidrug Resistance Proteins MRP1, MRP2, and MRP3
    Xiaoyan Chu, Su‐E. W. Huskey, Matthew P. Braun · 2004 · Journal of Pharmacology and Experimental Therapeutics
  148. One Intact ATP-binding Subunit Is Sufficient to Support ATP Hydrolysis and Translocation in an ABC Transporter, the Histidine Permease
    Kishiko Nikaido, Giovanna Ferro‐Luzzi Ames · 1999 · Journal of Biological Chemistry
  149. Ligand-mediated Tertiary Structure Changes of Reconstituted P-glycoprotein
    Nathalie Sonveaux, Catherine Vigano, Adam B. Shapiro · 1999 · Journal of Biological Chemistry
  150. Differential Interactions of Nucleotides at the Two Nucleotide Binding Domains of the Cystic Fibrosis Transmembrane Conductance Regulator
    Luba A. Aleksandrov, April E. Mengos, Xiu-bao Chang · 2001 · Journal of Biological Chemistry
  151. The Potential for an Interaction between MRP2 (ABCC2) and Various Therapeutic Agents: Probenecid as a Candidate Inhibitor of the Biliary Excretion of Irinotecan Metabolites
    Masato Horikawa, Yukio Kato, Charles A. Tyson, Yuichi Sugiyama · 2002 · Drug Metabolism and Pharmacokinetics
  152. Selective Protein Adduct Formation of Diclofenac Glucuronide Is Critically Dependent on the Rat Canalicular Conjugate Export Pump (Mrp2)
    Sven Seitz, Anke Kretz-Rommel, Ronald P.J. Oude Elferink, Urs Alex Boelsterli · 1998 · Chemical Research in Toxicology
  153. ATPase activity of purified and reconstituted multidrug resistance protein MRP1 from drug-selected H69AR cells
    Qingcheng Mao, Elaine M. Leslie, Roger G. Deeley, Susan P.C. Cole · 1999 · Biochimica et Biophysica Acta (BBA) - Biomembranes
  154. The Vinblastine Binding Site Adopts High- and Low-Affinity Conformations during a Transport Cycle of P-glycoprotein
    Catherine Martin, Christopher F. Higgins, Richard Callaghan · 2001 · Biochemistry
  155. Drug resistance and P-glycoprotein gene amplification in the protozoan parasite Leishmania
    Marc Ouellette, Piet Borst · 1991 · Research in Microbiology
  156. Expression and Localization of the Multidrug Resistance Protein 5 (MRP5/ABCC5), a Cellular Export Pump for Cyclic Nucleotides, in Human Heart
    Peter Dazert, Konrad Meissner, Silke Vogelgesang et al. · 2003 · American Journal Of Pathology
  157. Transport of bile acids in multidrug-resistance-protein 3-overexpressing cells co-transfected with the ileal Na+-dependent bile-acid transporter
    2002
  158. Functional Reconstitution of Substrate Transport by Purified Multidrug Resistance Protein MRP1 (ABCC1) in Phospholipid Vesicles
    Qingcheng Mao, Roger G. Deeley, Susan P.C. Cole · 2000 · Journal of Biological Chemistry
  159. The sulphonylurea glibenclamide inhibits multidrug resistance protein (MRP1) activity in human lung cancer cells
    Lea Francoise Payen, Laurence Delugin, Arnaud Courtois, Yolande Trinquart, André Guillouzo, Olivier Fardel · 2001 · British Journal of Pharmacology
  160. Nucleotide Occlusion in the Human Cystic Fibrosis Transmembrane Conductance Regulator
    Katalin Szabó, Gergely Szakács, Tamás Hegedűs · 1999 · Journal of Biological Chemistry
  161. Immunohistochemical detection of multidrug resistance protein in human lung cancer and normal lung.
    S. R. Wright, Alexander H. Boag, Gunnar Valdimarsson, David R. Hipfner, Barbara G. Campling, Susan P.C. Cole, R G Deeley · 1998 · PubMed
  162. Neuroblastoma: a clinical challenge and biologic puzzle
    Katherine K. Matthay · 1995 · CA A Cancer Journal for Clinicians
  163. Nonequivalent Nucleotide Trapping in the Two Nucleotide Binding Folds of the Human Multidrug Resistance Protein MRP1
    Koh Nagata, Masahito Nishitani, Michinori Matsuo · 2000 · Journal of Biological Chemistry
  164. MRP and MDR1 gene expression in primary breast carcinomas.
    Martin Filipits, Ralf W. Suchomel, Gerhard Dekan, Karin Haider, Gunnar Valdimarsson, Dieter Depisch, Robert Pirker · 1996 · PubMed
  165. The Distribution of Abcc6 in Normal Mouse Tissues Suggests Multiple Functions for this ABC Transporter
    Konstanze Beck, Kimiko Hayashi, Brian K. Nishiguchi, Olivier Le Saux, Masando Hayashi, Charles D. Boyd · 2003 · Journal of Histochemistry & Cytochemistry
  166. Effects of maturation on RNA transcription and protein expression of four MRP genes in human placenta and in BeWo cells
    Lorella Pascolo, Cristina Fernetti, Doroti Pirulli · 2003 · Biochemical and Biophysical Research Communications
  167. Clinical effects and P-glycoprotein inhibition in patients with acute myeloid leukemia treated with zosuquidar trihydrochloride, daunorubicin and cytarabine.
    Gareth Gerrard, Elspeth Payne, Robert J Baker et al. · 2004 · PubMed
  168. Differential effects of jaundice and cirrhosis on β-adrenoceptor signaling in three rat models of cirrhotic cardiomyopathy
    Zenghua Ma, Yikun Zhang, P.-Michel Huet · 1999 · Journal of Hepatology
  169. The canalicular conjugate export pump encoded by the cmrp/cmoat gene.
    Dietrich O. R. KEPPLER, Jürgen Kartenbeck · 1996 · PubMed
  170. Polymorphisms of MRP1 (ABCC1) and related ATP-dependent drug transporters
    Gwenaëlle Conseil, Roger G. Deeley, Susan P.C. Cole · 2005 · Pharmacogenetics and Genomics
  171. Expression of P-glycoprotein (ABCB1) and Mrp1 (ABCC1) in adult rat brain: focus on astrocytes
    Claire Mercier, Christophe Masseguin, Françoise S. Roux, Jacqueline Gabrion, Jean‐Michel Scherrmann · 2004 · Brain Research
  172. Role of glutathione in the multidrug resistance protein 4 (MRP4/ABCC4)-mediated efflux of cAMP and resistance to purine analogues
    Liqi LAI, Theresa May Chin Tan · 2002 · Biochemical Journal
  173. Normal gating of CFTR requires ATP binding to both nucleotide-binding domains and hydrolysis at the second nucleotide-binding domain
    Allan L. Berger, Mutsuhiro Ikuma, Michael J. Welsh · 2004 · Proceedings of the National Academy of Sciences
  174. Formation of the Productive ATP-Mg2+-bound Dimer of GlcV, an ABC-ATPase from Sulfolobus solfataricus
    Grégory Verdon, Sonja‐Verena Albers, Niels Van Oosterwijk · 2003 · Journal of Molecular Biology
  175. Alterations in glutathione and glutathione-related enzymes in a multidrug-resistant small cell lung cancer cell line.
    Susan P.C. Cole, H F Downes, Shelagh E. L. Mirski, Douglas Clements · 1990 · Molecular Pharmacology
  176. Double knockout of the MRP gene leads to increased drug sensitivity in vitro.
    Aurelio Lorico, Germana Rappa, Richard Anthony Flavell, Alan C. Sartorelli · 1996 · PubMed
  177. The Packing of the Transmembrane Segments of Human Multidrug Resistance P-glycoprotein Is Revealed by Disulfide Cross-linking Analysis
    Tip W. Loo, David M. Clarke · 2000 · Journal of Biological Chemistry
  178. The multidrug resistance-associated protein 3 (MRP3) is associated with a poor outcome in childhood ALL and may account for the worse prognosis in male patients and T-cell immunophenotype
    Daniel Steinbach, Susann Wittig, Gunnar Cario, Susanne F. Viehmann, A H Mueller, Bernd Gruhn, Ralf Haefer, F Zintl, Axel Sauerbrey · 2003 · Blood
  179. Various Methods of Analysis of mdr-1/P-Glycoprotein in Human Colon Cancer Cell Lines
    Cynthia E. Herzog, Jane B. Trepel, Lyn A. Mickley · 1992 · JNCI Journal of the National Cancer Institute
  180. Identification of an Amino Acid Residue in Multidrug Resistance Protein 1 Critical for Conferring Resistance to Anthracyclines
    Dawei Zhang, Susan P.C. Cole, Roger G. Deeley · 2001 · Journal of Biological Chemistry
  181. A Yeast ATP-binding Cassette-type Protein Mediating ATP-dependent Bile Acid Transport
    Daniel F. Ortiz, Marie V. St.-Pierre, Aida Abdulmessih, Irwin M. Arias · 1997 · Journal of Biological Chemistry
  182. MYCN-mediated regulation of the MRP1 promoter in human neuroblastoma
    Chitra F. Manohar, James A Bray, Helen R. Salwen, Janice Madafiglio, Andy J. Cheng, Claudia L. Flemming, Glenn M. Marshall, Murray D. Norris, Michelle Haber, Susan Lerner Cohn · 2004 · Oncogene
  183. Properties of highly purified leukotriene C4 synthase of guinea pig lung.
    Takayuki Yoshimoto, Roy J. Soberman, Bernd Werner Spur · 1988 · Journal of Clinical Investigation
  184. Functional consequences of mutations in the conserved ‘signature sequence’ of the ATP‐binding‐cassette protein MalK
    Günter Schmees, Anke Stein, Sabine Hunke, Heidi Landmesser, Erwin Schneider · 1999 · European Journal of Biochemistry
  185. Buthionine sulphoximine-mediated sensitisation of etoposide-resistant human breast cancer MCF7 cells overexpressing the multidrug resistance-associated protein involves increased drug accumulation
    Erasmus Schneider, Hiroyuki Yamazaki, Sinha Bk · 1995 · British Journal of Cancer
  186. Protection of platinum–DNA adduct formation and reversal of cisplatin resistance by anti‐MRP2 hammerhead ribozymes in human cancer cells
    Verena Materna, Bernd Liedert, Jürgen Thomale · 2005 · International Journal of Cancer
  187. Multidrug Resistance Protein
    Mian Gao, Masayo Yamazaki, Douglas W. Loe, Christopher J. Westlake, Caroline E. Grant, Susan P.C. Cole, Roger G. Deeley · 1998 · Journal of Biological Chemistry
  188. Expression of MRP1, LRP and Pgp in breast carcinoma patients treated with preoperative chemotherapy
    Margaretha Rudas, Martin Filipits, Susanne Taucher, Thomas Stranzl, Günther Georg Steger, R. Jakesz, Robert Pirker, Gudrun Pohl · 2003 · Breast Cancer Research and Treatment
  189. Rhodamine 123 Binds to Multiple Sites in the Multidrug Resistance Protein (MRP1)
    Roni Daoud, Christina Kast, Piet Gros · 2000 · Biochemistry
  190. Production of Leukotriene C4 in Different Human Tissues Is Attributable to Distinct Membrane Bound Biosynthetic Enzymes
    Kylie A. Scoggan, Per‐Johan Jakobsson, Anthony W. Ford‐Hutchinson · 1997 · Journal of Biological Chemistry
  191. Identification of Basic Residues Involved in Drug Export Function of Human Multidrug Resistance-associated Protein 2
    Sunghi Ryu, Tetsuhiro Kawabe, Shigeyuki Nada, Akihito Yamaguchi · 2000 · Journal of Biological Chemistry
  192. INDUCTION OF MULTIDRUG RESISTANCE PROTEIN 3 IN RAT LIVER IS ASSOCIATED WITH ALTERED VECTORIAL EXCRETION OF ACETAMINOPHEN METABOLITES
    Angela Lucas Slitt, Nathan J. Cherrington, Jonathan M. Maher, Curtis D. Klaassen · 2003 · Drug Metabolism and Disposition
  193. Analysis of the Intron–Exon Organization of the Human Multidrug-Resistance Protein Gene (MRP) and Alternative Splicing of Its mRNA
    Caroline E. Grant, Ebba U. Kurz, Susan P.C. Cole, Roger G. Deeley · 1997 · Genomics
  194. Monoclonal Antibodies That Inhibit the Transport Function of the 190-kDa Multidrug Resistance Protein, MRP
    David R. Hipfner, Qingcheng Mao, Wei Qiu, Elaine M. Leslie, Mian Gao, Roger G. Deeley, Susan P.C. Cole · 1999 · Journal of Biological Chemistry
  195. Functional characterization of non-synonymous single nucleotide polymorphisms in the gene encoding human multidrug resistance protein 1 (MRP1/ABCC1)
    Isabelle J. Létourneau, Roger G. Deeley, Susan P.C. Cole · 2005 · Pharmacogenetics and Genomics
  196. Role of Carboxylate Residues Adjacent to the Conserved Core Walker B Motifs in the Catalytic Cycle of Multidrug Resistance Protein 1 (ABCC1)
    Lea Francoise Payen, Mian Gao, Christopher J. Westlake · 2003 · Journal of Biological Chemistry
  197. Studies on Pyrrolopyrimidines as Selective Inhibitors of Multidrug-Resistance- Associated Protein in Multidrug Resistance
    Shouming Wang, Adrian J. Folkes, Irina Chuckowree, Xiaoling F. Cockcroft, Sukhjit Sohal, Warren Miller, John Milton, Stephen P. Wren, Nigel Vicker, Paul Depledge et al. · 2004 · Journal of Medicinal Chemistry
  198. ATP-binding cassette superfamily transporter gene expression in human primary ovarian carcinoma.
    Yoshihiro Ohishi, Yoshinao Oda, Takeshi Uchiumi, Hiroaki Kobayashi, Toshio Hirakawa, Shingo Miyamoto, Naoko Kinukawa, Hitoo Nakano, Michihiko Kuwano, Masazumi Tsuneyoshi · 2002 · PubMed
  199. Potent interaction of flavopiridol with MRP1
    Jan Hendrik Hooijberg, Henk J. Broxterman, George L. Scheffer, C Vrasdonk, Marc Heijn, Mariska C. de Jong, Rik J. Scheper, Jan Lankelma, Herbert M. Pinedo · 1999 · British Journal of Cancer
  200. Mutational Analysis of Conserved Carboxylate Residues in the Nucleotide Binding Sites of P-Glycoprotein
    Ina L. Urbatsch, Michel Julien, Isabelle Carrier · 2000 · Biochemistry