(Patho)physiological Significance of the Serum- and Glucocorticoid-Inducible Kinase Isoforms

Lang, Florian, Böhmer, Christoph, Palmada, Monica, Seebohm, Guiscard, Strutz-Seebohm, Nathalie, Vallon, Volker·2006·Physiological Reviews

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Items 101–200 of 687

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  2. Weighing In on mTOR Complex 2 Signaling: The Expanding Role in Cell Metabolism
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  3. ENaC in Salt-Sensitive Hypertension: Kidney and Beyond
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  4. Determination of SGK1 mRNA in non-small cell lung cancer samples underlines high expression in squamous cell carcinomas
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  5. Regulation of ENaC-mediated sodium transport by glucocorticoids in Reissner's membrane epithelium
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  6. Ischemic preconditioning attenuates ischemia/reperfusion-induced kidney injury by activating autophagy via the SGK1 signaling pathway
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  7. Sodium-retaining effect of insulin in diabetes
    Michael W. Brands, Marlina M Manhiani · 2012 · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology
  8. Role and Regulation of the Serum- and Glucocorticoid-Regulated Kinase 1 in Fertile and Infertile Human Endometrium
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  9. Serum- and Glucocorticoid-Inducible Kinase 1 (SGK1) Regulates Adipocyte Differentiation via Forkhead Box O1
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  10. SI113, a SGK1 inhibitor, potentiates the effects of radiotherapy, modulates the response to oxidative stress and induces cytotoxic autophagy in human glioblastoma multiforme cells
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  11. Physiologic regulation of the epithelial sodium channel by phosphatidylinositides
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  12. A Rheostat of Ceramide and Sphingosine-1-Phosphate as a Determinant of Oxidative Stress-Mediated Kidney Injury
    Norishi Ueda · 2022 · International Journal of Molecular Sciences
  13. SGK2 promotes prostate cancer metastasis by inhibiting ferroptosis via upregulating GPX4
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  14. Regulation of STIM1/Orai1-dependent Ca2+ signalling in platelets
    Patrick Münzer, Meinrad Gawaz, Oliver Borst, Florian Lang · 2013 · Thrombosis and Haemostasis
  15. 17β-estradiol suppresses lipopolysaccharide-induced acute lung injury through PI3K/Akt/SGK1 mediated up-regulation of epithelial sodium channel (ENaC) in vivo and in vitro
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  16. mTORC2: a multifaceted regulator of autophagy
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  17. SGK3 Is an Estrogen-Inducible Kinase Promoting Estrogen-Mediated Survival of Breast Cancer Cells
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  18. Regulation of Orai1/STIM1 by the kinases SGK1 and AMPK
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  19. Genistein Inhibits Human Colorectal Cancer Growth and Suppresses MiR-95, Akt and SGK1
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  20. Inhibition of Colonic Tumor Growth by the Selective SGK Inhibitor EMD638683
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  21. Pivotal Role of Serum- and Glucocorticoid-Inducible Kinase 1 in Vascular Inflammation and Atherogenesis
    Oliver Borst, Malte Schaub, Britta Walker, Evi Schmid, Patrick Münzer, Jakob G. J. Voelkl, Ioana Alesutan, José M. Rodríguez, Sebastian Vogel, Tanja Schoenberger et al. · 2015 · Arteriosclerosis Thrombosis and Vascular Biology
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  23. Effect of aldosterone on BK channel expression in mammalian cortical collecting duct
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  24. Regulation of transport across cell membranes by the serum- and glucocorticoid-inducible kinase SGK1
    Lang, Florian, Stournaras, Christos, Alesutan, Ioana · 2014 · Molecular Membrane Biology
  25. Serum- and glucocorticoid-regulated kinase 1 is upregulated following unilateral ureteral obstruction causing epithelial–mesenchymal transition
    Jizhong Cheng, Luan D. Truong, Xiaoqian Wu, Dietmar Kuhl, Florian J.W. Lang, Jie Du · 2010 · Kidney International
  26. Serum- and glucocorticoid-inducible kinase 1 and the response to cell stress
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  28. Glucocorticoid induces human beta cell dysfunction by involving riborepressor GAS5 LincRNA
    Jonathan L.S. Esguerra, Jones K. Ofori, Mototsugu Nagao, Yuki Shuto, Alexandros Karagiannopoulos, João Fadista, Hitoshi Sugihara, Leif Groop, Lena Eliasson · 2019 · Molecular Metabolism
  29. Aldosterone stimulates nuclear factor-kappa B activity and transcription of intercellular adhesion molecule-1 and connective tissue growth factor in rat mesangial cells via serum- and glucocorticoid-inducible protein kinase-1
    Yoshio Terada, Satoko Ueda, Kazu Hamada, Yoshiko Shimamura, Koji Ogata, Kosuke Inoue, Yoshinori Taniguchi, Toru Kagawa, Taro Horino, Toshihiro Takao · 2011 · Clinical and Experimental Nephrology
  30. SGK3 Regulates Ca2+Entry and Migration of Dendritic Cells
    Evi Schmid, Madhuri Bhandaru, Meerim K. Nurbaeva, Wenting Yang, Kalina Szteyn, Antonella Russo, Christina B. Leibrock, Leonid Tyan, David Pearce, Ekaterina V. Shumilina et al. · 2012 · Cellular Physiology and Biochemistry
  31. Baicalin decreases SGK1 expression in the hippocampus and reverses depressive-like behaviors induced by corticosterone
    Y.-C. Li, L.-L. Wang, Yang-yi Pei, J.-D. Shen, H.-B. Li, B.-Y. Wang, M. Bai · 2015 · Neuroscience
  32. Mineralocorticoid receptor activation in obesity hypertension
    Miki Nagase, Toshiro Fujita · 2009 · Hypertension Research
  33. PIKfyve in the SGK1 Mediated Regulation of the Creatine Transporter SLC6A8
    Nathalie Strutz‐Seebohm, Manzar Banoo Shojaeifard, David L. Christie, Jeremy M. Tavaré, Guiscard Seebohm, Florian J.W. Lang · 2007 · Cellular Physiology and Biochemistry
  34. Serum/glucocorticoid-induced protein kinase-1 facilitates androgen receptor-dependent cell survival
    Ilanchezian Shanmugam, G Cheng, Paul F. Terranova, James Brantley Thrasher, Christie P. Thomas, Benyi Li · 2007 · Cell Death and Differentiation
  35. Ion homeostasis in the ear: mechanisms, maladies, and management
    Dennis R. Trune · 2010 · Current Opinion in Otolaryngology & Head & Neck Surgery
  36. Association of SGK1 Gene Polymorphisms with Type 2 Diabetes
    Matthias Georg Schwab, Adrian Lupescu, Maria Moța, Eugen Moța, Andreas Frey, Perikles D. Simon, Peter Rene Mertens, Jürgen Floege, Friedrich Cameron Luft, S. Asante-Poku et al. · 2008 · Cellular Physiology and Biochemistry
  37. Abnormal expression of ENaC and SGK1 mRNA induced by dietary sodium in Dahl salt‐sensitively hypertensive rats
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  38. Sgk1 enhances RANBP1 transcript levels and decreases taxol sensitivity in RKO colon carcinoma cells
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  39. Phosphorylation at distinct subcellular locations underlies specificity in mTORC2-mediated activation of SGK1 and Akt
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  40. The Peptide Transporter PEPT2 is Targeted by the Protein Kinase SGK1 and the Scaffold Protein NHERF2
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  42. Therapeutic inhibition of SGK1 suppresses colorectal cancer
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  43. Hyperactivity and Enhanced Curiosity of Mice Expressing PKB/SGK-resistant Glycogen Synthase Kinase-3 (GSK-3)
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  47. The prospect of serum and glucocorticoid-inducible kinase 1 (SGK1) in cancer therapy: a rising star
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  48. High-fat diet-induced activation of SGK1 promotes Alzheimer’s disease-associated tau pathology
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  50. Cholesterol Depletion of the Plasma Membrane Prevents Activation of the Epithelial Sodium Channel (ENaC) by SGK1
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  51. A brain-specific SGK1 splice isoform regulates expression of ASIC1 in neurons
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  52. Aldosterone responsiveness of the epithelial sodium channel (ENaC) in colon is increased in a mouse model for Liddle's syndrome
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  53. Global Expression Analysis Identified a Preferentially Nerve Growth Factor-induced Transcriptional Program Regulated by Sustained Mitogen-activated Protein Kinase/Extracellular Signal-regulated Kinase (ERK) and AP-1 Protein Activation during PC12 Cell Differentiation*
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  55. The mTOR signaling pathway as a treatment target for intracranial neoplasms
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  56. Regulation of the Glutamate Transporter EAAT2 by PIKfyve
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  58. Serum- and glucocorticoid-induced kinase 3 in recycling endosomes mediates acute activation of Na+/H+exchanger NHE3 by glucocorticoids
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  59. Activation of the cardiac mTOR/p70 S6K pathway by leucine requires PDK1 and correlates with PRAS40 phosphorylation
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  60. The Mechanical Stress–Activated Serum-, Glucocorticoid-Regulated Kinase 1 Contributes to Neointima Formation in Vein Grafts
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  61. NFκB-sensitive Orai1 expression in the regulation of FGF23 release
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  62. mSIN1 Protein Mediates SGK1 Protein Interaction with mTORC2 Protein Complex and Is Required for Selective Activation of the Epithelial Sodium Channel
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  63. PDK1 Regulates Vascular Remodeling and Promotes Epithelial-Mesenchymal Transition in Cardiac Development
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  64. REGULATION OF EPITHELIAL Na+CHANNELS BY ALDOSTERONE: ROLE OF Sgk1
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  65. PF-03882845, a non-steroidal mineralocorticoid receptor antagonist, prevents renal injury with reduced risk of hyperkalemia in an animal model of nephropathy
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  66. The SGK1 inhibitor SI113 induces autophagy, apoptosis, and endoplasmic reticulum stress in endometrial cancer cells
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  74. Sgk1 sensitivity of Na+/H+ exchanger activity and cardiac remodeling following pressure overload
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  75. Relative resistance of SGK1 knockout mice against chemical carcinogenesis
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  78. Dapagliflozin reverses the imbalance of T helper 17 and T regulatory cells by inhibiting SGK1 in a mouse model of diabetic kidney disease
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  79. Differential Regulation of Serum- and Glucocorticoid-Inducible Kinase 1 (SGK1) Splice Variants Based on Alternative Initiation of Transcription
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  82. PIKfyve Sensitivity of hERG Channels
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  83. Glucose Activates TORC2-Gad8 Protein via Positive Regulation of the cAMP/cAMP-dependent Protein Kinase A (PKA) Pathway and Negative Regulation of the Pmk1 Protein-Mitogen-activated Protein Kinase Pathway
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  84. From Pinocytosis to Methuosis—Fluid Consumption as a Risk Factor for Cell Death
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  85. SGK1 inhibits cellular apoptosis and promotes proliferation<i>via</i>the MEK/ERK/p53 pathway in colitis
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  86. Phosphopeptide Screen Uncovers Novel Phosphorylation Sites of Nedd4-2 That Potentiate Its Inhibition of the Epithelial Na+ Channel
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  87. Spinal SGK1/GRASP-1/Rab4 is involved in complete Freund’s adjuvant-induced inflammatory pain via regulating dorsal horn GluR1-containing AMPA receptor trafficking in rats
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  88. Multiple translational isoforms give functional specificity to serum- and glucocorticoid-induced kinase 1
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  89. Discovery of N-[4-(1H-Pyrazolo[3,4-b]pyrazin-6-yl)-phenyl]-sulfonamides as Highly Active and Selective SGK1 Inhibitors
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  92. Impact of Aldosterone on Osteoinductive Signaling and Vascular Calcification
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  93. Glucocorticoids Enhance Intestinal Glucose Uptake Via the Dimerized Glucocorticoid Receptor in Enterocytes
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  94. Molecular determinants of uterine receptivity
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  95. Estradiol Suppresses TLR4-triggered Apoptosis of Decidual Stromal Cells and Drives an Anti-inflammatory T H 2 Shift by Activating SGK1
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  96. Serum and glucocorticoid‐inducible kinase 1 (SGK1) is necessary for vascular remodeling during angiogenesis
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  97. Rapamycin-induced phosphaturia
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