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Cited by 58Pain Management and Opioid UsePain Mechanisms and TreatmentsPain Management and Treatment

The DOI matches its Crossref record; 55 of the 55 references it cites were found in a registry or an index.

Use of Lidocaine Patches for Neuropathic Pain in a Comprehensive Cancer Centre

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Fleming, Julia Ann, O’Connor, Bradley David·2009·Pain Research and Management
DOI 10.1155/2009/723179PMC PMC2779156
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Abstract

BACKGROUND: There are few reports of the use of the lidocaine 5% patch (L5%P) for neuropathic pain (NP) in the cancer patient. Within a comprehensive cancer centre, L5%P has been prescribed by the Pain and Palliative Care Service (Peter McCallum Cancer Centre, East Melbourne, Victoria, Australia) for selected patients with NP since 2001. OBJECTIVE: To retrospectively audit the use of L5%P within a comprehensive cancer centre. METHODS: All L5%P prescriptions up to January 2009 were listed and patient medical records were searched to determine neuropathic pain syndromes treated, the presence of allodynia, previous analgesic medications, treatment duration and outcome. RESULTS: L5%P was prescribed for 97 patients, most frequently for persistent postsurgical NP (n=26), postherpetic neuralgia (n=24) and cancer‐related NP (n=18). Six patients had no history of cancer and two patients never applied L5%P. Reviewers classed L5%P analgesic efficacy as ‘potent’ in 38% of patients with postherpetic neuralgia, 35% of patients with postsurgical pain, 27% of patients with NP after other treatments for cancer and 12% of patients with NP attributed to cancer alone. Allodynia featured in at least 60% of patients. Where allodynia was present, the efficacy of L5%P was assessed as ‘potent’ in 38% and ‘partial’ in 24%, but ‘ineffective’ in 26%, and ‘causing worse pain’ in 3.4% of patients. Treatment duration extended longer than one month in 52 patients, longer than two months in 29 patients and longer than one year in 13 patients. Therapy was ceased due to skin irritation in seven patients. The outcomes in relation to other reports are discussed. CONCLUSION: The present data support trials of L5%P for cancer patients with NP syndromes associated with allodynia.

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  1. Davis MD, Sandroni P. Lidocaine patch for pain of erythromelalgia: Follow-up of 34 patients. Arch Dermatol 2005;141:1320-1.

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Metadata

Authors
Fleming, J. A., & O’Connor, B. D.
Affiliations
  • Royal Brisbane and Women's Hospital (AU)
  • Northern Hospital (AU)
Corresponding author
Fleming, Julia Ann
Venue
Pain Research and Management
Publisher
Wiley
Published
2009-01
Volume
14
Issue
5
Pages
381-388
ISSN
  • 1203-6765 (ISSN-L)
  • 1918-1523
DOI
10.1155/2009/723179
PMC
PMC2779156
OpenAlex
W2302262350
Cited by
58
References
55
Citations by year
2025: 2 · 2024: 2 · 2023: 3 · 2022: 3 · 2021: 3 · 2020: 2 · 2019: 6 · 2018: 5 · 2017: 4 · 2016: 6 · 2015: 4 · 2014: 2 · 2013: 5 · 2012: 6
FWCI
4.23
Type
journal article
Language
en
Open access
Licence
Locations
  • Pain Research and Management (publishedVersion, cc-by)
  • PubMed Central (publishedVersion)
  • PubMed (publishedVersion)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
Topics
  • Health Sciences › Medicine › Anesthesiology and Pain Medicine › Pain Management and Opioid Use
  • Health Sciences › Medicine › Physiology (medical) › Pain Mechanisms and Treatments
  • Health Sciences › Medicine › Anesthesiology and Pain Medicine › Pain Management and Treatment
Keywords
lidocaine patch, neuropathic pain, cancer pain, postherpetic neuralgia, postoperative pain, allodynia, analgesic efficacy, treatment duration, skin irritation, palliative care
MeSH terms
Adult, Aged, Aged, 80 and over, Anesthetics, Local, Female, Humans, Hyperalgesia, Lidocaine, Male, Middle Aged, Neoplasms, Neuralgia, Pain Measurement, Retrospective Studies, Time Factors, Pain Threshold, Young Adult

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