The DOI matches its Crossref record; 116 of the 116 references it cites were found in a registry or an index.
Managing Dyspnea in Patients with Advanced Chronic Obstructive Pulmonary Disease: A Canadian Thoracic Society Clinical Practice Guideline
Open accessAbstract
Dyspnea is a cardinal symptom of chronic obstructive pulmonary disease (COPD), and its severity and magnitude increases as the disease progresses, leading to significant disability and a negative effect on quality of life. Refractory dyspnea is a common and difficult symptom to treat in patients with advanced COPD. There are many questions concerning optimal management and, specifically, whether various therapies are effective in this setting. The present document was compiled to address these important clinical issues using an evidence-based systematic review process led by a representative interprofessional panel of experts. The evidence supports the benefits of oral opioids, neuromuscular electrical stimulation, chest wall vibration, walking aids and pursed-lip breathing in the management of dyspnea in the individual patient with advanced COPD. Oxygen is recommended for COPD patients with resting hypoxemia, but its use for the targeted management of dyspnea in this setting should be reserved for patients who receive symptomatic benefit. There is insufficient evidence to support the routine use of anxiolytic medications, nebulized opioids, acupuncture, acupressure, distractive auditory stimuli (music), relaxation, hand-held fans, counselling programs or psychotherapy. There is also no evidence to support the use of supplemental oxygen to reduce dyspnea in nonhypoxemic patients with advanced COPD. Recognizing the current unfamiliarity with prescribing and dosing of opioid therapy in this setting, a potential approach for their use is illustrated. The role of opioid and other effective therapies in the comprehensive management of refractory dyspnea in patients with advanced COPD is discussed.
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Citations
Cites
1 retracted
Bausewein, C., Booth, S., Gysels, M., & Higginson, I. J. (2013) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd005623.pub3 · Cited by 284
RetractedVestbo, J., Hurd, S. S., Agustí, A. G., Jones, P. W., Vogelmeier, C., Anzueto, A., Barnes, P. J., Fabbri, L. M., Martinez, F. J., Nishimura, M., et al. (2013) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.201204-0596pp · Cited by 15,983
Rabe, K. F., Hurd, S., Anzueto, A., Barnes, P. J., Buist, S. A., Calverley, P., Fukuchi, Y., Jenkins, C., Rodriguez-Roisin, R., van Weel, C., et al. (2007) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.200703-456so · Cited by 4,925
Celli, B. R., MacNee, W., Agusti, A., Anzueto, A., Berg, B., Buist, A. S., Calverley, P. M. A., Chavannes, N., Dillard, T., Fahy, B., et al. (2004) · European Respiratory Journal · doi:10.1183/09031936.04.00014304 · Cited by 4,421
AGREE II: advancing guideline development, reporting and evaluation in health care
Brouwers, M. C., Kho, M. E., Browman, G. P., Burgers, J. S., Cluzeau, F., Feder, G., Fervers, B., Graham, I. D., Grimshaw, J., Hanna, S. E., et al. (2010) · Canadian Medical Association Journal · doi:10.1503/cmaj.090449 · Cited by 3,790
Rabe, K. F. (2007) · American Journal of Respiratory and Critical Care Medicine · Cited by 2,567
A new system for grading recommendations in evidence based guidelines
Harbour, R., & Miller, J. (2001) · BMJ · doi:10.1136/bmj.323.7308.334 · Cited by 1,637
Rodríguez, R. (2007) · Cited by 1,412
Ries, A. L., Bauldoff, G. S., Carlin, B. W., Casaburi, R., Emery, C. F., Mahler, D. A., Make, B., Rochester, C. L., ZuWallack, R., & Herrerias, C. (2007) · Chest · doi:10.1378/chest.06-2418 · Cited by 1,306
Grading Strength of Recommendations and Quality of Evidence in Clinical Guidelines
Guyatt, G., Gutterman, D., Baumann, M. H., Addrizzo-Harris, D., Hylek, E. M., Phillips, B., Raskob, G., Lewis, S. Z., & Schünemann, H. (2006) · Chest · doi:10.1378/chest.129.1.174 · Cited by 1,220
Cited by
Parshall, M. B., Schwartzstein, R. M., Adams, L., Banzett, R. B., Manning, H. L., Bourbeau, J., Calverley, P. M., Gift, A. G., Harver, A., Lareau, S. C., et al. (2012) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.201111-2042st · Cited by 1,844
Self-citationPollok, J., van Agteren, J. E., & Carson-Chahhoud, K. V. (2018) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd012346.pub2 · Cited by 59
Metadata
- Authors
- Marciniuk, D. D., Goodridge, D., Hernandez, P., Rocker, G., Balter, M., Bailey, P., Ford, G., Bourbeau, J., O’Donnell, D. E., Maltais, F., Mularski, R. A., Cave, A. J., Mayers, I., Kennedy, V., Oliver, T. K., Brown, C., & Canadian Thoracic Society COPD Committee Dyspnea Expert Working Group
- Venue
- Canadian Respiratory Journal
- Publisher
- Wiley
- Published
- 2011
- Volume
- 18
- Issue
- 2
- Pages
- 69-78
- ISSN
- 1198-2241 (ISSN-L)
- OpenAlex
- W2146250410
- Cited by
- 264
- References
- 116
- FWCI
- 11.14
- Type
- journal article
- Language
- en
- Open access
- gold
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- CoChat. (2026). Citation check: Managing Dyspnea in Patients with Advanced Chronic Obstructive Pulmonary Disease: A Canadian Thoracic Society Clinical Practice Guideline. https://app.cochat.ai/papers/10.1155/2011/745047
- The paper
- Marciniuk, D. D., Goodridge, D., Hernandez, P., Rocker, G., Balter, M., Bailey, P., Ford, G., Bourbeau, J., O’Donnell, D. E., Maltais, F., Mularski, R. A., Cave, A. J., Mayers, I., Kennedy, V., Oliver, T. K., Brown, C., & Canadian Thoracic Society COPD Committee Dyspnea Expert Working Group. (2011). Managing Dyspnea in Patients with Advanced Chronic Obstructive Pulmonary Disease: A Canadian Thoracic Society Clinical Practice Guideline. Canadian Respiratory Journal. https://doi.org/10.1155/2011/745047
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
