Acupuncture Effect and Central Autonomic Regulation
Open accessAbstract
Acupuncture is a therapeutic technique and part of traditional Chinese medicine (TCM). Acupuncture has clinical efficacy on various autonomic nerve-related disorders, such as cardiovascular diseases, epilepsy, anxiety and nervousness, circadian rhythm disorders, polycystic ovary syndrome (PCOS) and subfertility. An increasing number of studies have demonstrated that acupuncture can control autonomic nerve system (ANS) functions including blood pressure, pupil size, skin conductance, skin temperature, muscle sympathetic nerve activities, heart rate and/or pulse rate, and heart rate variability. Emerging evidence indicates that acupuncture treatment not only activates distinct brain regions in different kinds of diseases caused by imbalance between the sympathetic and parasympathetic activities, but also modulates adaptive neurotransmitter in related brain regions to alleviate autonomic response. This review focused on the central mechanism of acupuncture in modulating various autonomic responses, which might provide neurobiological foundations for acupuncture effects.
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In response to brain hypoxia, the individual experiences a change in level of consciousness ranging from compromised consciousness to complete loss of consciousness (syncope).
“In response to brain hypoxia, the individual also experiences a change in his or her level of consciousness, ranging from compromised consciousness to a complete loss of consciousness (syncope).116,117”
From Fear and the Defense Cascade (2015) · cites this paper as [117]
Section 2.2 discusses brainstem control of blood pressure, and Section 2.1 discusses hypothalamic autonomic regulation, but neither addresses changes in consciousness caused by brain hypoxia. Searches for brain hypoxia, syncope, and loss of consciousness found no passage in our copy that supports the attributed claim. (LLM, conf=0.76)
Experimental — accuracy not yet measuredIn some individuals, cerebral hypoxia can compromise inhibitory control and manifest as increased anxiety, panic, weeping, or moaning.
“In some individuals cerebral hypoxia can compromise inhibitory control and manifest as increased anxiety, panic, weeping, or moaning.116,117”
From Fear and the Defense Cascade (2015) · cites this paper as [117]
Section 2.4 discusses prefrontal activity and responses to stress, but does not discuss cerebral hypoxia or loss of inhibitory control. Searches for hypoxia, oxygen deprivation, and the listed emotional symptoms found no passage linking them in our copy; page numbers were not available. (LLM, conf=0.73)
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Cites
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Haker, E., Egekvist, H., & Bjerring, P. (2000) · Journal of the Autonomic Nervous System · doi:10.1016/s0165-1838(99)00090-9 · Cited by 306 · see citing works
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Sorted by citations
Kozlowska, K., Walker, P., McLean, L., & Carrive, P. (2015) · Harvard Review of Psychiatry · doi:10.1097/hrp.0000000000000065 · Cited by 468 · see citing works
The autonomic nervous system: A potential link to the efficacy of acupuncture
Li, Y.-W., Li, W., Wang, S.-T., Gong, Y.-N., Dou, B.-M., Lyu, Z.-X., Ulloa, L., Wang, S.-J., Xu, Z.-F., & Guo, Y. (2022) · Frontiers in Neuroscience · doi:10.3389/fnins.2022.1038945 · Cited by 141 · see citing works
- Authors
- Li, Q.-Q., Shi, G.-X., Xu, Q., Wang, J., Liu, C.-Z., & Wang, L.-P.
- Affiliations
- Acupuncture and Moxibustion Department, Beijing Hospital of Traditional Chinese Medicine affiliated to Capital Medical University, 23 Meishuguanhou Street, Dongcheng District, Beijing 100010, China
- Capital Medical University (CN)
- Corresponding author
- Liu, Cun-Zhi
- Venue
- Evidence-Based Complementary and Alternative Medicine
- Publisher
- Wiley
- Published
- 2013
- Volume
- 2013
- Pages
- 1-6
- ISSN
- 1741-427X (ISSN-L)
- 1741-4288
- PMC
- PMC3677642
- OpenAlex
- W1977293811
- Cited by
- 138
- References
- 2
- Citations by year
- 2026: 6 · 2025: 12 · 2024: 11 · 2023: 13 · 2022: 13 · 2021: 13 · 2020: 14 · 2019: 12 · 2018: 14 · 2017: 6 · 2016: 11 · 2015: 7 · 2014: 2 · 2013: 4
- FWCI
- 18.91
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Locations
- Evidence-based Complementary and Alternative Medicine (publishedVersion, cc-by)
- Europe PMC (PubMed Central) (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- Funders
- New Century Excellent Talents in University (NCET-09-0007, 2009B46)
- Technology New Star Program of Beijing (NCET-09-0007, 2009B46)
- Topics
- Health Sciences › Medicine › Complementary and alternative medicine › Acupuncture Treatment Research Studies
- Health Sciences › Medicine › Complementary and alternative medicine › Traditional Chinese Medicine Studies
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Heart Rate Variability and Autonomic Control
- Keywords
- acupuncture, autonomic nervous system, central autonomic regulation, sympathetic and parasympathetic balance, cardiovascular disease, epilepsy, anxiety, circadian rhythm disorders, polycystic ovary syndrome, subfertility, heart rate variability, skin conductance, muscle sympathetic nerve activity, neurotransmitter modulation, neurobiological mechanisms
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