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Current Diagnostic and Therapeutic Aspects of Eosinophilic Myocarditis
Open accessAbstract
Eosinophilic myocarditis (EM) represents a rare form of myocardial inflammation with very heterogeneous aetiology. In developed countries, the most prevalent causes of EM are hypersensitivity or allergic reactions, as well as hematological diseases leading to eosinophilia. The disease may have a variable clinical presentation, ranging from asymptomatic forms to life-threatening conditions. Most patients with EM have marked eosinophilia in peripheral blood. Endomyocardial biopsy needs to be performed in most cases in order to establish a definitive diagnosis of EM. The therapy depends on the underlying aetiology. Immunosuppressive therapy represents the treatment mainstay in the majority of EM forms.
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“leading to advanced heart disorders such as heart failure, fibrosis, and thrombosis.”
From Autoimmune Myocarditis, Old Dogs and New Tricks. (2024) · cites this paper as [195]
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“various conditions including infections, drugs, hypersensitivity, and autoimmune factors may be associated with the onset and progress of this disease.”
From Autoimmune Myocarditis, Old Dogs and New Tricks. (2024) · cites this paper as [195]
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“Eosinophilic myocarditis is characterized by a predominant infiltration of eosinophils in the myocardium”
From Autoimmune Myocarditis, Old Dogs and New Tricks. (2024) · cites this paper as [195]
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Cited by
Sorted by citations
Autoimmune Myocarditis, Old Dogs and New Tricks.
Won, T., Song, E. J., Kalinoski, H. M., Moslehi, J. J., & Čiháková, D. (2024) · Circulation Research · doi:10.1161/circresaha.124.323816 · Cited by 51
Metadata
- Authors
- Kuchynka, P., Palecek, T., Masek, M., Cerny, V., Lambert, L., Vitkova, I., & Linhart, A.
- Affiliations
- Charles University (CZ)
- 2nd Department of Medicine-Department of Cardiovascular Medicine, First Faculty of Medicine, Charles University in Prague and General University Hospital in Prague, U Nemocnice 2, 128 08 Prague 2, Czech Republic
- Department of Radiology, First Faculty of Medicine, Charles University in Prague and General University Hospital in Prague, U Nemocnice 2, 128 08 Prague 2, Czech Republic
- Institute of Pathology, First Faculty of Medicine, Charles University in Prague and General University Hospital in Prague, U Nemocnice 2, 128 08 Prague 2, Czech Republic
- ORCID
- Kuchynka, Petr
- Venue
- BioMed Research International
- Publisher
- Wiley
- Published
- 2016
- Volume
- 2016
- Pages
- 1-6
- ISSN
- 1110-7243 (ISSN-L)
- 2314-6133
- 2314-6141
- PMC
- PMC4738989
- OpenAlex
- W2274823306
- Cited by
- 96
- References
- 0
- Citations by year
- 2026: 5 · 2025: 7 · 2024: 9 · 2023: 13 · 2022: 13 · 2021: 11 · 2020: 13 · 2019: 8 · 2018: 7 · 2017: 7 · 2016: 2
- FWCI
- 8.51
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Locations
- BioMed Research International (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion)
- Funders
- OP Prague Competitiveness (PRVOUK-P35/LF1/5)
- Topics
- Health Sciences › Medicine › Rheumatology › Eosinophilic Disorders and Syndromes
- Health Sciences › Medicine › Infectious Diseases › Viral Infections and Immunology Research
- Health Sciences › Medicine › Gastroenterology › Eosinophilic Esophagitis
- Keywords
- eosinophilic myocarditis, eosinophilia, hypersensitivity, allergic reactions, hematologic disorders, endomyocardial biopsy, immunosuppressive therapy, myocarditis, etiology
- MeSH terms
- Biopsy, Eosinophilia, Eosinophils, Glucocorticoids, Humans, Immunosuppressive Agents, Inflammation, Myocarditis
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- The paper
- Kuchynka, P., Palecek, T., Masek, M., Cerny, V., Lambert, L., Vitkova, I., & Linhart, A. (2016). Current Diagnostic and Therapeutic Aspects of Eosinophilic Myocarditis. BioMed Research International. https://doi.org/10.1155/2016/2829583
