Radical-Scavenging Activity and Ferric Reducing Ability of Juniperus thurifera(L.),J. oxycedrus(L.),J. phoenicea(L.) and Tetraclinis articulata(L.)
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Objective. The aim of this work is to study and compare the antioxidant properties and phenolic contents of aqueous leaf extracts of Juniperus thurifera,Juniperus oxycedrus,Juniperus Phoenicea,and Tetraclinis articulata from Morocco.Methods. Antioxidant activities of the extracts were evaluated by 2,2-diphenyl-1-picrylhydrazyl (DPPH) free radical-scavenging ability, Trolox equivalent antioxidant capacity (TEAC), and ferric reducing antioxidant power (FRAP) assays. Also the total phenolic and flavonoids contents of the extracts were determined spectrophotometrically.Results. All the extracts showed interesting antioxidant activities compared to the standard antioxidants (butylated hydroxytoluene (BHT), quercetin, and Trolox). The aqueous extract of Juniperus oxycedrus showed the highest antioxidant activity as measured by DPPH, TEAC, and FRAP assays with IC 50 values of17.91±0.37 μ g/mL,19.80±0.55 μ g/mL, and24.23±0.07 μ g/mL, respectively. The strong correlation observed between antioxidant capacities and their total phenolic contents indicated that phenolic compounds were a major contributor to antioxidant properties of these plants extracts.Conclusion. These results suggest that the aqueous extracts of Juniperus thurifera,Juniperus oxycedrus,Juniperus phoenicea,and Tetraclinis articulata can constitute a promising new source of natural compounds with antioxidants ability.
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Phenolic compounds and antioxidant activity in plants have a synergistic relationship.
“The synergistic relationship between phenolic compounds and antioxidant activity in plants has also been elucidated [69–71].”
From Comparative and Correlational Evaluation of the Phytochemical Constituents and Antioxidant Activity of <i>Musa sinensis</i> L. and <i>Musa paradisiaca</i> L. Fruit Compartments (Musaceae) (2020) · cites this paper as [70]
Results §3.5 (page not supplied) reports strong correlations between phenolic content and antioxidant activity in four Moroccan Cupressaceae samples. The Discussion says phenolic compounds largely contribute to their antioxidant activity, but neither passage establishes a synergistic interaction; correlation and contribution do not demonstrate synergy. (LLM, conf=0.88)
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Oyeyinka, B. O., & Afolayan, A. J. (2020) · The Scientific World JOURNAL · doi:10.1155/2020/4503824 · Cited by 25 · see citing works
- Authors
- El Jemli, M., Kamal, R., Marmouzi, I., Zerrouki, A., Cherrah, Y., & Alaoui, K.
- Affiliations
- Pharmacodynamy Research Team, ERP, Laboratory of Pharmacology and Toxicology, Faculty of Medicine and Pharmacy, Mohammed V University, BP 6203, Rabat-Instituts, Rabat, Morocco
- Mohammed V University (MA)
- Venue
- Advances in Pharmacological Sciences
- Publisher
- Wiley
- Published
- 2016
- Volume
- 2016
- Pages
- 1-6
- ISSN
- 1687-6334 (ISSN-L)
- 1687-6342
- PMC
- PMC4884791
- OpenAlex
- W2408190394
- Cited by
- 99
- References
- 2
- Citations by year
- 2026: 1 · 2025: 6 · 2024: 19 · 2023: 13 · 2022: 15 · 2021: 19 · 2020: 17 · 2019: 3 · 2018: 5 · 2017: 1
- FWCI
- 2.36
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Locations
- Advances in Pharmacological Sciences (publishedVersion, cc-by)
- Europe PMC (PubMed Central) (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Greater South Information System
- Funders
- Université Mohammed V de Rabat
- Topics
- Health Sciences › Medicine › Biochemistry › Phytochemicals and Antioxidant Activities
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Medicinal Plant Research
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Phytochemistry and Biological Activities
- Keywords
- Juniperus thurifera, Juniperus oxycedrus, Juniperus phoenicea, Tetraclinis articulata, antioxidant activity, free radical scavenging, ferric reducing antioxidant power, total phenolic content, flavonoids, aqueous leaf extract, natural antioxidants
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