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Cited by 316

The DOI matches its Crossref record; 217 of the 217 references it cites were found in a registry or an index.

Eosinophils from Physiology to Disease: A Comprehensive Review

Open access
Ramirez, Giuseppe A., Yacoub, Mona-Rita, Ripa, Marco, Mannina, Daniele, Cariddi, Adriana, Saporiti, Nicoletta, Ciceri, Fabio, Castagna, Antonella, Colombo, Giselda, Dagna, Lorenzo·2018·BioMed Research International

Abstract

Despite being the second least represented granulocyte subpopulation in the circulating blood, eosinophils are receiving a growing interest from the scientific community, due to their complex pathophysiological role in a broad range of local and systemic inflammatory diseases as well as in cancer and thrombosis. Eosinophils are crucial for the control of parasitic infections, but increasing evidence suggests that they are also involved in vital defensive tasks against bacterial and viral pathogens including HIV. On the other side of the coin, eosinophil potential to provide a strong defensive response against invading microbes through the release of a large array of compounds can prove toxic to the host tissues and dysregulate haemostasis. Increasing knowledge of eosinophil biological behaviour is leading to major changes in established paradigms for the classification and diagnosis of several allergic and autoimmune diseases and has paved the way to a “golden age” of eosinophil-targeted agents. In this review, we provide a comprehensive update on the pathophysiological role of eosinophils in host defence, inflammation, and cancer and discuss potential clinical implications in light of recent therapeutic advances.

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Registry

Crossref · 10.1155/2018/9095275

Cites

217 of 217 references verified0 citation errors · 0 not checkable

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Citations

Cites

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Metadata

Authors
Ramirez, G. A., Yacoub, M.-R., Ripa, M., Mannina, D., Cariddi, A., Saporiti, N., Ciceri, F., Castagna, A., Colombo, G., & Dagna, L.
Venue
BioMed Research International
Publisher
Wiley
Published
2018
Volume
2018
Pages
1-28
ISSN
  • 1110-7243 (ISSN-L)
  • 2314-6133
  • 2314-6141
OpenAlex
W2785409534
Cited by
316
References
217
FWCI
16.03
Type
journal article
Language
en
Open access
hybrid

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CoChat. (2026). Citation check: Eosinophils from Physiology to Disease: A Comprehensive Review. https://app.cochat.ai/papers/10.1155/2018/9095275
The paper
Ramirez, G. A., Yacoub, M.-R., Ripa, M., Mannina, D., Cariddi, A., Saporiti, N., Ciceri, F., Castagna, A., Colombo, G., & Dagna, L. (2018). Eosinophils from Physiology to Disease: A Comprehensive Review. BioMed Research International. https://doi.org/10.1155/2018/9095275

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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