Inhibition of Fatty Acid Synthase Attenuates CD44-Associated Signaling and Reduces Metastasis in Colorectal Cancer

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Wéry, C., Montero‐Ruiz, L., Bonneil, É., Farran, M., Jehay, R., Garfia, Q. H., Fettweis, G., Blacher, S., Pottier, C., Cobraiville, G., et al. (2026) · MedComm · doi:10.1002/mco2.70809 · Cited by 1

A Cellular Assay for Inhibitors of the Fatty Acid Biosynthetic Pathway Using Scintillating Microplates

Ung, T., Mason, J. L., Robinson, R. G., Spais, C. M., Ator, M. A., & Angeles, T. S. (2015) · Assay and Drug Development Technologies · doi:10.1089/adt.2015.644 · Cited by 1

NFYA promotes the malignant behavior of triple-negative breast cancer through the regulation of lipid metabolismPreprint

Okada, N., Ueki, C., Shimazaki, M., Tsujimoto, G., Kohno, S., Muranaka, H., Yoshikawa, K., & Takahashi, C. (2022) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2022.05.26.493660 · Cited by 1

Inhibition of fatty acid synthase enhances therapeutic efficacy and delays acquired resistance to BRAF-targeted therapy in colorectal cancer

Geisen, M. E., Tessmann, J. W., Kelson, C. O., He, D., Wang, C., Faisal, A. S. M., Beswick, E. J., Baca, Y., Rock, S., Kolesar, J. M., et al. (2026) · Neoplasia · doi:10.1016/j.neo.2026.101283

Characteristic prediction of colorectal cancer using multi-modality and multi-biomarker imaging

Wang, H., & Tian, J. (2018) · Clinical and Medical Investigations · doi:10.15761/cmi.1000170

Brain Metastasis of Colorectal Cancer: Microenvironment and Molecular Mechanism

Chen, Z., Gu, X., & Zang, Y.-W. (2015) · Elsevier eBooks · doi:10.1016/b978-0-12-801419-6.00016-1

Role of NMR Metabolomics and MR Imaging in Colon Cancer

Kumar, P., & Kumar, V. (2021) · Springer eBooks · doi:10.1007/978-3-030-63369-1_4

DELINEATING THE ROLE OF FATTY ACID METABOLISM TO IMPROVE THERAPEUTIC STRATEGIES FOR COLORECTAL CANCER

Drury, J. (2021) · UKnowledge (University of Kentucky) · doi:10.13023/etd.2021.370

FASN-Deficiency Induces a Cytosol-to-Mitochondria Citrate Flux to Mitigate Oxidative Stress During Metastatic TransitionPreprint

Dai, W., Wang, Z., Wang, G., Wang, Q. A., DeBerardinis, R. J., & Jiang, L. (2022) · SSRN Electronic Journal · doi:10.2139/ssrn.4164244

Data from SIRT1-Mediated Expression of CD24 and Epigenetic Suppression of Novel Tumor Suppressor miR-1185-1 Increases Colorectal Cancer Stemness

Wang, T., Chern, E., Hsu, C., Tseng, K.-C., & Chao, H. (2023) · doi:10.1158/0008-5472.c.6511714.v1

Data from SIRT1-Mediated Expression of CD24 and Epigenetic Suppression of Novel Tumor Suppressor miR-1185-1 Increases Colorectal Cancer Stemness

Wang, T., Chern, E., Hsu, C., Tseng, K.-C., & Chao, H. (2023) · doi:10.1158/0008-5472.c.6511714

Prognostic role of CHEK2, FASN and Her2/neu Expression in Stage Ta-T1 Non-Muscle-Invasive Bladder Cancer (NMIBC)

Elaidy, N. F., Abdelbary, A. M., Qasem, E. R., Eliwa, A., & Ibrahim, H. (2023) · The Egyptian Journal of Hospital Medicine · doi:10.21608/ejhm.2023.305065

ATF6 activation alters colonic lipid metabolism causing tumor-associated microbial adaptationPreprint

Coleman, O. I., Sorbie, A., Riva, A., von Stern, M., Kuhls, S., Selegato, D. M., Köhler, N., Wirbel, J., Kacprowski, T., Dunkel, A., et al. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.11.03.565267

Potential Application Value of FASN in the Diagnosis of Colorectal Cancer

Li, N., Hu, M., Qian, Q., Ouyang, J., Yang, Y., & Zhang, Y. (2025) · JGH Open · doi:10.1002/jgh3.70261

Additional file 4 of LncRNA RPARP-AS1 promotes the progression of osteosarcoma cells through regulating lipid metabolism

Cai, F., Liu, L., Bo, Y., Yan, W., Tao, X., Peng, Y., Zhang, Z., Liao, Q., & Yi, Y. (2024) · Figshare · doi:10.6084/m9.figshare.26675876

Additional file 2 of Identification of fatty acid metabolism-related lncRNAs in the prognosis and immune microenvironment of colon adenocarcinoma

Wu, S., Gong, Y., Chen, J., Zhao, X., Qing, H., Dong, Y., Li, S., Li, J., & Wang, Z. (2022) · Figshare · doi:10.6084/m9.figshare.20400909

Additional file 3 of Identification of fatty acid metabolism-related lncRNAs in the prognosis and immune microenvironment of colon adenocarcinoma

Wu, S., Gong, Y., Chen, J., Zhao, X., Qing, H., Dong, Y., Li, S., Li, J., & Wang, Z. (2022) · Figshare · doi:10.6084/m9.figshare.20400912

Additional file 1 of LncRNA RPARP-AS1 promotes the progression of osteosarcoma cells through regulating lipid metabolism

Cai, F., Liu, L., Bo, Y., Yan, W., Tao, X., Peng, Y., Zhang, Z., Liao, Q., & Yi, Y. (2024) · Figshare · doi:10.6084/m9.figshare.25137964

Additional file 2 of LncRNA RPARP-AS1 promotes the progression of osteosarcoma cells through regulating lipid metabolism

Cai, F., Liu, L., Bo, Y., Yan, W., Tao, X., Peng, Y., Zhang, Z., Liao, Q., & Yi, Y. (2024) · Figshare · doi:10.6084/m9.figshare.25138041

Abstract 1467: The potential role of de novo lipogenesis in the regulation of cell motility and invasion in colorectal cancer

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De Novo Fatty Acid Synthesis-Driven Sphingolipid Metabolism Promotes Metastatic Potential of Colorectal Cancer

Jafari, N., Drury, J., Morris, A. J., Onono, F. O., Stevens, P. D., Gao, T., Liu, J., Wang, C., Lee, E. Y., Weiss, H. L., et al. (2018) · Molecular Cancer Research · doi:10.1158/1541-7786.mcr-18-0199 · Cited by 69

Abstract 1687 The Effect of Fatty Acid Synthase Inhibition on mTOR Signaling in Colorectal Cancer

Skau, M., Banerjee, M., Gao, T., & Hedinger, K. (2025) · Journal of Biological Chemistry · doi:10.1016/j.jbc.2025.108674

Tissue-Specific Downregulation of Fatty Acid Synthase Suppresses Intestinal Adenoma Formation via Coordinated Reprograming of Transcriptome and Metabolism in the Mouse Model of Apc-Driven Colorectal Cancer

Drury, J., Young, L. E. A., Scott, T. L., Kelson, C. O., He, D., Liu, J., Wu, Y., Wang, C., Weiss, H. L., Fan, T. W. ‐., et al. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23126510 · Cited by 22

Fatty acid synthase regulates invasion and metastasis of colorectal cancer via Wnt signaling pathway

Wang, H., Xi, Q., & Wu, G. (2016) · Cancer Medicine · doi:10.1002/cam4.711 · Cited by 96