The ISB Cancer Genomics Cloud: A Flexible Cloud-Based Platform for Cancer Genomics Research
Open accessPublished version of a preprint
Abstract
The ISB Cancer Genomics Cloud (ISB-CGC) is one of three pilot projects funded by the National Cancer Institute to explore new approaches to computing on large cancer datasets in a cloud environment. With a focus on Data as a Service, the ISB-CGC offers multiple avenues for accessing and analyzing The Cancer Genome Atlas, TARGET, and other important references such as GENCODE and COSMIC using the Google Cloud Platform. The open approach allows researchers to choose approaches best suited to the task at hand: from analyzing terabytes of data using complex workflows to developing new analysis methods in common languages such as Python, R, and SQL; to using an interactive web application to create synthetic patient cohorts and to explore the wealth of available genomic data. Links to resources and documentation can be found at www.isb-cgc.org. Cancer Res; 77(21); e7–10. ©2017 AACR.
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References 14 · Cited by 63
Research works printed but not linked: 2
- [12]Melnik S Gubarev A Long JJ Romer G Shivakumar S Tolton M Dremel: Interactive Analysis of Web-Scale Datasets Proc. of the 36th Int'l Conf on Very Large Data Bases 2010 330 339
- [13]Wickham H Tidy Data Journal of Statistical Software 2014 59 10 1 23
- Authors
- Reynolds, S. M., Miller, M., Lee, P., Leinonen, K., Paquette, S. M., Rodebaugh, Z., Hahn, A., Gibbs, D. L., Slagel, J., Longabaugh, W. J., Dhankani, V., Reyes, M., Pihl, T., Backus, M., Bookman, M., Deflaux, N., Bingham, J., Pot, D., & Shmulevich, I.
- Affiliations
- Institute for Systems Biology (US)
- 2CSRA Inc., Falls Church, Virginia.
- Google (United States) (US)
- Corresponding author
- Reynolds, Sheila M.
- Shmulevich, Ilya
- ORCID
- Venue
- Cancer Research
- Published
- 2017-10-31
- Volume
- 77
- Issue
- 21
- Pages
- e7-e10
- ISSN
- 0008-5472 (ISSN-L)
- 1538-7445
- PMC
- PMC5780183
- OpenAlex
- W2765285264
- Cited by
- 63
- References
- 14
- Citations by year
- 2026: 1 · 2025: 6 · 2024: 9 · 2023: 2 · 2022: 8 · 2021: 7 · 2020: 13 · 2019: 7 · 2018: 9 · 2017: 1
- FWCI
- 2.74
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- other-oa
- Locations
- Cancer Research (publishedVersion, other-oa)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- NCI NIH (HHSN261201400007C)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cancer Research › Cancer Genomics and Diagnostics
- Physical Sciences › Computer Science › Information Systems › Cloud Computing and Resource Management
- Social Sciences › Decision Sciences › Information Systems and Management › Scientific Computing and Data Management
- Keywords
- cloud computing, cancer genomics, data as a service, TCGA, targets, GENCODE, COSMIC, Google Cloud Platform, genomic data access, bioinformatics platform
- MeSH terms
- Cloud Computing, Humans, Neoplasms, Research, Software, United States, Genome, Human, Computational Biology, Internet, Genomics, National Cancer Institute (U.S.), Datasets as Topic
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