The DOI matches its Crossref record; 38 of the 38 references it cites were found in a registry or an index.
The Role of Tomato Products and Lycopene in the Prevention of Prostate Cancer: A Meta-Analysis of Observational Studies
Abstract
Purpose: To determine whether intake of tomato products reduces the risk of prostate cancer using a meta-analysis. Methods: We systematically searched MEDLINE and EMBASE and contacted authors to identify potential studies. Log relative risks (RRs) were weighed by the inverse of their variances to obtain a pooled estimate with its 95% confidence interval (CI). Logistic regression and Poisson regression analyses were used to determine the effect produced by a daily intake of one serving of tomato product. Results: Eleven case-control studies and 10 cohort studies or nested case-control studies presented data on the use of tomato, tomato products, or lycopene and met our inclusion criteria. Compared with nonfrequent users of tomato products (1st quartile of intake), the RR of prostate cancer among consumers of high amounts of raw tomato (5th quintile of intake) was 0.89 (95% CI 0.80–1.00). For high intake of cooked tomato products, this RR was 0.81 (95% CI 0.71–0.92). The RR of prostate cancer related to an intake of one serving/day of raw tomato (200 g) was 0.97 (95% CI 0.85–1.10) for the case-control studies and 0.78 (95% CI 0.66–0.92) for cohort studies. Conclusion: Our results show that tomato products may play a role in the prevention of prostate cancer. However, this effect is modest and restricted to high amounts of tomato intake. Further research is needed to determine the type and quantity of tomato products with respect to their role in preventing prostate cancer.
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Cites
Intake of Carotenoids and Retino in Relation to Risk of Prostate Cancer
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A Prospective Study of Tomato Products, Lycopene, and Prostate Cancer Risk
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β-Carotene and Other Carotenoids as Antioxidants
Paiva, S. A. R., & Russell, R. M. (1999) · Journal of the American College of Nutrition · doi:10.1080/07315724.1999.10718880 · Cited by 822
Tomato lycopene and its role in human health and chronic diseases.
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Fruit and Vegetable Intakes and Prostate Cancer Risk
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Lycopene is more bioavailable from tomato paste than from fresh tomatoes
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Cited by
Potential Role of Carotenoids as Antioxidants in Human Health and Disease
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The strawberry: Composition, nutritional quality, and impact on human health
Giampieri, F., Tulipani, S., Alvarez-Suarez, J. M., Quiles, J. L., Mezzetti, B., & Battino, M. (2012) · Nutrition · doi:10.1016/j.nut.2011.08.009 · Cited by 1,044
The Epidemiology of Prostate Cancer
Pernar, C. H., Ebot, E. M., Wilson, K. M., & Mucci, L. A. (2018) · Cold Spring Harbor Perspectives in Medicine · doi:10.1101/cshperspect.a030361 · Cited by 773
The Tomato As a Functional Food
Canene-Adams, K., Campbell, J. K., Zaripheh, S., Jeffery, E. H., & Erdman, J. W. (2005) · The Journal of Nutrition · doi:10.1093/jn/135.5.1226 · Cited by 416
Dietary phytochemicals and cancer chemoprevention: a review of the clinical evidence
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Metadata
- Authors
- Etminan, M., Takkouche, B., & Caamaño-Isorna, F.
- Venue
- Cancer Epidemiology, Biomarkers & Prevention
- Published
- 2004-03-01
- Volume
- 13
- Issue
- 3
- Pages
- 340-345
- ISSN
- 1055-9965 (ISSN-L)
- 1538-7755
- OpenAlex
- W2097048367
- Cited by
- 425
- References
- 38
- FWCI
- 4.00
- Type
- journal article
- Language
- en
- Open access
- closed
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- Etminan, M., Takkouche, B., & Caamaño-Isorna, F. (2004). The Role of Tomato Products and Lycopene in the Prevention of Prostate Cancer: A Meta-Analysis of Observational Studies. Cancer Epidemiology, Biomarkers & Prevention. https://doi.org/10.1158/1055-9965.340.13.3
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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