Successful Use of Gonadotropin-Releasing Hormone Agonist in a Patient with Pulmonary Endometriosis
Abstract
A 26-year-old single female was admitted to hospital with recurrent chest pain, cough and hemoptysis. The symptoms developed 5 months before admission coinciding with menstruation. The disease was diagnosed as pulmonary endometriosis. She was treated with a long-acting gonadotropin-releasing hormone analogue (GnRH agonist; sustained-release leuprolide acetate, 3.75 mg/month, i.m.) for 6 months. She remained asymptomatic for 16 months with regular menstruation even after discontinuing the treatment. This indicates that the initial treatment of pulmonary endometriosis with a GnRH agonist is an acceptable medical alternative, especially in patients with a short duration of the disease from the onset of the chest symptoms.
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No difference in efficacy has been demonstrated between GnRH analogs and alternative medications for TES.
“No difference in efficacy has been demonstrated between these medications.53,54”
From Thoracic Endometriosis Syndrome: A Review of Diagnosis and Management (2019) · cites this paper as [54]
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References 10 · Cited by 23
- Authors
- Koizumi, T., Inagaki, H., Takabayashi, Y., & Kubo, K.
- Affiliations
- Shinshu University (JP)
- Venue
- Respiration
- Publisher
- S. Karger AG
- Published
- 1999
- Volume
- 66
- Issue
- 6
- Pages
- 544-546
- ISSN
- 0025-7931 (ISSN-L)
- 1423-0356
- OpenAlex
- W2082323105
- Cited by
- 23
- References
- 10
- Citations by year
- 2025: 2 · 2024: 1 · 2021: 1 · 2019: 2 · 2018: 1 · 2016: 1 · 2015: 1 · 2014: 2
- FWCI
- 0.34
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Respiration (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Reproductive Medicine › Endometriosis Research and Treatment
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Pleural and Pulmonary Diseases
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Medical Imaging and Pathology Studies
- Keywords
- pulmonary endometriosis, GnRH agonist, leuprolide, medical management, chest pain, hemoptysis, menstrual cycle, treatment duration
- MeSH terms
- Adult, Delayed-Action Preparations, Drug Administration Schedule, Endometriosis, Female, Follow-Up Studies, Humans, Lung Diseases, Tomography, X-Ray Computed, Leuprolide
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