The DOI matches its Crossref record.
Antimicrobial Activity of Fluoride and Its in vivo Importance: Identification of Research Questions
Abstract
This manuscript discusses the antimicrobial activity of fluoride and its in vivo importance in order to identify research questions. There is a lot of information on mechanisms by which fluoride may interfere with bacterial metabolism and dental plaque acidogenicity. The antimicrobial activity of fluoride products is enhanced when fluoride is associated with antimicrobial cations like Sn 2+ and amine. It is not clear whether the antimicrobial mechanisms of fluoride are operating in vivo or even to what extent antimicrobial activity can contribute to caries prevention. This latter question may be the most important one in research.
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“Fluoride may be beneficial or harmful to the gut microbiome depending upon the doses ingested, transit time, and duration of exposure.1,18”
From Effect of Fluoride on Gut Microbiota: A Systematic Review (2025) · cites this paper as [18]
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A review of the effects of stannous fluoride on gingivitis
Paraskevas, S., & Van Der Weijden, G. A. (2006) · Journal Of Clinical Periodontology · doi:10.1111/j.1600-051x.2005.00860.x · Cited by 94
Effect of Fluoride on Gut Microbiota: A Systematic Review
Yasin, M., Zohoori, F. V., Kumah, E. A., Subramanian, M., Dean, P., & Orr, C. H. (2025) · Nutrition Reviews · doi:10.1093/nutrit/nuae202 · Cited by 8
Metadata
- Authors
- van Loveren, C.
- Venue
- Caries Research
- Publisher
- S. Karger AG
- Published
- 2001
- Volume
- 35
- Issue
- Suppl. 1
- Pages
- 65-70
- ISSN
- 0008-6568
- 1421-976X
- Cited by
- 100
- References
- 0
- Language
- en
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Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
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