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Effect of a Lactose-Containing Sweetener on Root Dentine Demineralization in situ

Aires, C.P., Tabchoury, C.P.M., Del Bel Cury, A.A., Cury, J.A.·2002·Caries Research
DOI 10.1159/000059331
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Abstract

Since lactose has been used as an excipient in powdered sweeteners, we evaluated its effect on dentine demineralization, in an in situ crossover study. Twelve adult volunteers wore palatal appliances containing 4 blocks of bovine root dentine, which were submitted 4 times a day to: distilled water (negative control), aqueous solution of powdered sweetener (Zero Cal®; experimental group), 1.5% lactose solution (active group), 1.5% sucrose solution (positive control). After 15 days, microhardness was determined on dentine surface (SMH) and on the sectioned blocks (CSMH). All groups presented statistical differences in SMH before and after the treatments; water increased, while sweetener, lactose and sucrose decreased SMH. By CSMH, the only significant difference was observed after sucrose treatment. The data suggest that sweeteners containing lactose as a bulking agent may be cariogenic for root dentine.

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  • The use of surface hardness as an indicator of dentine mineral loss has been widely employed because there is a high correlation with transversal microradiography, which directly quantifies demineralization in dental enamel and also in dentine.

    “About the use of surface hardness as indicator of dentine mineral loss, it has been widely employed [25, 33, 34, 36, 39, 56–59] because there is a high correlation with transversal microradiography [25], which directly quantifies demineralization in dental enamel and also in dentine [60].”

    From Validation of a Cariogenic Biofilm Model to Evaluate the Effect of Fluoride on Enamel and Root Dentine Demineralization (2016) · cites this paper as [56]

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Research works printed but not linked: 2

  1. 10.1159/000016629 · DOI · Paper page
  2. 10.1016/0003-9969(87)90085-9 · DOI

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Metadata

Authors
Aires, C. P., Tabchoury, C. P. M., Del Bel Cury, A. A., & Cury, J. A.
Venue
Caries Research
Publisher
S. Karger AG
Published
2002
Volume
36
Issue
3
Pages
167-169
ISSN
  • 0008-6568
  • 1421-976X
DOI
10.1159/000059331
Cited by
20
References
0
Language
en
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