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Cited by 472

The DOI matches its Crossref record; 29 of the 29 references it cites were found in a registry or an index.

Modeling of Protein Interaction Networks

Vázquez, Alexei, Flammini, Alessandro, Maritan, Amos, Vespignani, Alessandro·2003·Complexus

Abstract

We introduce a graph-generating model aimed at representing the evolution of protein interaction networks. The model is based on the hypothesis of evolution by duplication and divergence of the genes which produce proteins. The obtained graphs have multifractal properties recovering the absence of a characteristic connectivity as found in real data of protein interaction networks. The error tolerance of the model to random or targeted damage is in very good agreement with the behavior obtained in real protein network analyses. The proposed model is a first step in the identification of the evolutionary dynamics leading to the development of protein functions and interactions.

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Metadata

Authors
Vázquez, A., Flammini, A., Maritan, A., & Vespignani, A.
Venue
Complexus
Publisher
S. Karger AG
Published
2002-12-11
Volume
1
Issue
1
Pages
38-44
ISSN
  • 1424-8492 (ISSN-L)
  • 1424-8506
OpenAlex
W2084668512
Cited by
472
References
29
FWCI
5.29
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Modeling of Protein Interaction Networks. https://app.cochat.ai/papers/10.1159/000067642
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Vázquez, A., Flammini, A., Maritan, A., & Vespignani, A. (2003). Modeling of Protein Interaction Networks. Complexus. https://doi.org/10.1159/000067642

Data sources

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.