The DOI matches its Crossref record; 14 of the 14 references it cites were found in a registry or an index.
Inactivation of SARS coronavirus by means of povidone-iodine, physical conditions and chemical reagents.
Open accessAbstract
The efficacy of several povidone-iodine (PVP-I) products, a number of other chemical agents and various physical conditions were evaluated for their ability to inactivate the severe acute respiratory syndrome coronavirus (SARS-CoV). Treatment of SARS-CoV with PVP-I products for 2 min reduced the virus infectivity from 1.17 x 10(6) TCID(50)/ml to below the detectable level. The efficacy of 70% ethanol was equivalent to that of PVP-I products. Fixation of SARS-CoV-infected Vero E6 cells with a fixative including formalin, glutaraldehyde, methanol and acetone for 5 min or longer eliminated all infectivity. Heating the virus at 56 degrees C for 60 min or longer reduced the infectivity of the virus from 2.6 x 10(7) to undetectable levels. Irradiation with ultraviolet light at 134 microW/cm(2) for 15 min reduced the infectivity from 3.8 x 10(7) to 180 TCID(50)/ml; however, prolonged irradiation (60 min) failed to eliminate the remaining virus, leaving 18.8 TCID(50)/ml.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“Studies have also shown that SARS-CoV, MERS-CoV, and influenza virus A (H1N1) can be efficiently inactivated by these compounds within 1 min (Kariwa et al., 2006; Eggers et al., 2015, 2018; Kampf et al., 2020; Li and Meng, 2020).”
From Oral Microbiome and SARS-CoV-2: Beware of Lung Co-infection (2020) · cites this paper as Kariwa et al., 2006
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
A SIMPLE METHOD OF ESTIMATING FIFTY PER CENT ENDPOINTS
Reed, L., & Muench, H. (1938) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a118408 · Cited by 17,629
A simple method of estimating 50 per cent end points
Muench, H. (1938) · Medical Entomology and Zoology · Cited by 8,376
Identification of a novel coronavirus in patients with severe acute respiratory syndrome
Drosten, C., Günther, S., Preiser, W., van der Werf, S., Brodt, H.-R., Becker, S., Rabenau, H., Panning, M., Kolesnikova, L., Fouchier, R. A. M., et al. (2003) · New England Journal of Medicine · doi:10.1056/nejmoa030747 · Cited by 4,574
A Novel Coronavirus Associated with Severe Acute Respiratory Syndrome
Tg, K., Erdman, D. D., Cs, G., Zaki, Peret, T. C. T., Emery, S. L., Tong, S., Urbani, C., Comer, J. A., Lim, W., et al. (2003) · New England Journal of Medicine · doi:10.1056/nejmoa030781 · Cited by 4,353
Coronavirus as a possible cause of severe acute respiratory syndrome
Peiris, M. J. S., Lai, S., Poon, L. L. M., Guan, Y., Yam, L., Lim, W., Nicholls, J. M., Yee, W., Yan, W., Cheung, M., et al. (2003) · The Lancet · doi:10.1016/s0140-6736(03)13077-2 · Cited by 2,916
Characterization of a Novel Coronavirus Associated with Severe Acute Respiratory Syndrome
Rota, P. A., Oberste, M. S., Monroe, S. S., Nix, W. A., Campagnoli, R. P., Icenogle, J. P., Peñaranda, S., Bankamp, B., Maher, K., Chen, M., et al. (2003) · Science · doi:10.1126/science.1085952 · Cited by 2,477
Guan, Y., Zheng, B., He, Y., Liu, X. L., Zhuang, Z. X., Cheung, C. L., Luo, S., Li, P. H., Zhang, L., Guan, Y., et al. (2003) · Science · doi:10.1126/science.1087139 · Cited by 2,404
Evidence of Airborne Transmission of the Severe Acute Respiratory Syndrome Virus
Yu, I. T. S., Li, Y., Wong, T. W., Tam, W., Chan, A., Lee, J. H. W., Leung, D. Y. C., & Ho, T. (2004) · New England Journal of Medicine · doi:10.1056/nejmoa032867 · Cited by 1,255
Identification of Severe Acute Respiratory Syndrome in Canada
Poutanen, S. M., Low, D. E., Henry, B., Finkelstein, S., Rose, D. E., Green, K., Tellier, R., Draker, R., Adachi, D., Ayers, M., et al. (2003) · New England Journal of Medicine · doi:10.1056/nejmoa030634 · Cited by 1,133
Detection of SARS Coronavirus in Patients with Suspected SARS
Chan, K. H., Poon, L. L. M., Cheng, V. C., Guan, Y., Hung, I. F., Kong, J. H. B., Yam, L. Y.-C., Seto, W., Yuen, K., & Peiris, J. S. M. (2004) · Emerging infectious diseases · doi:10.3201/eid1002.030610 · Cited by 313
Flagged first, then by citations
Cited by
Sorted by citations
Persistence of coronaviruses on inanimate surfaces and their inactivation with biocidal agents.
Kampf, G., Todt, D., Pfaender, S., & Steinmann, E. (2020) · Journal of Hospital Infection · doi:10.1016/j.jhin.2020.01.022 · Cited by 3,796
Guideline for disinfection and sterilization in healthcare facilities, 2008
Rutala, W. A., & Weber, D. J. (2008) · Infection Control and Hospital Epidemiology · Cited by 1,402
Coronavirus Disease 19 (COVID-19): Implications for Clinical Dental Care
Ather, A., Patel, B., Ruparel, N. B., Diogenes, A. R., & Hargreaves, K. (2020) · Journal of Endodontics · doi:10.1016/j.joen.2020.03.008 · Cited by 930
Raeiszadeh, M., & Adeli, B. (2020) · ACS Photonics · doi:10.1021/acsphotonics.0c01245 · Cited by 476
Aboubakr, H. A., Sharafeldin, T. A., & Goyal, S. M. (2020) · Transboundary and Emerging Diseases · doi:10.1111/tbed.13707 · Cited by 439
Metadata
- Authors
- Kariwa, H., Fujii, N., & Takashima, I.
- Affiliations
- Hokkaido University (JP)
- Sapporo Medical University (JP)
- ORCID
- Kariwa, Hiroaki
- Venue
- Dermatology
- Publisher
- S. Karger AG
- Published
- 2006
- Volume
- 212
- Issue
- Suppl. 1
- Pages
- 119-123
- ISSN
- 1018-8665 (ISSN-L)
- 1421-9832
- PMC
- PMC7179540
- OpenAlex
- W2129667078
- Cited by
- 458
- References
- 14
- Citations by year
- 2026: 1 · 2025: 5 · 2024: 15 · 2023: 17 · 2022: 60 · 2021: 111 · 2020: 221 · 2018: 3 · 2017: 1 · 2015: 6 · 2014: 1 · 2013: 1 · 2012: 2
- FWCI
- 2.36
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Dermatology (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Institutional Repositories DataBase (IRDB) (submittedVersion)
- Hokkaido University Collection of Scholarly and Academic Papers (Hokkaido University) (submittedVersion)
- PubMed
- Topics
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Infection Control and Ventilation
- Health Sciences › Medicine › Infectious Diseases › Infection Control in Healthcare
- Health Sciences › Medicine › Infectious Diseases › SARS-CoV-2 and COVID-19 Research
- Keywords
- SARS coronavirus, povidone-iodine, virus inactivation, ethanol, formalin fixation, glutaraldehyde, thermal inactivation, UV irradiation, disinfectants, Vero E6 cells, viral infectivity
- MeSH terms
- Ethanol, Animals, Anti-Infective Agents, Local, Chlorocebus aethiops, Disinfection, Fixatives, Hot Temperature, Povidone-Iodine, Ultraviolet Rays, Vero Cells, Infection Control, Virus Inactivation, Severe Acute Respiratory Syndrome, Severe acute respiratory syndrome-related coronavirus
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
