The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Isolation and Characterization of a Population of Immature Dental Pulp Stem Cells Expressing OCT-4 and Other Embryonic Stem Cell Markers
Abstract
We report the isolation of a population of immature dental pulp stem cells (IDPSC), which express embryonic stem cell markers Oct-4, Nanog, SSEA-3, SSEA-4, TRA-1-60 and TRA-1-81 as well as several other mesenchymal stem cell markers during at least 25 passages while maintaining the normal karyotype and the rate of expansion characteristic of stem cells. The expression of these markers was maintained in subclones obtained from these cells. Moreover, in vitrothese cells can be induced to undergo uniform differentiation into smooth and skeletal muscles, neurons, cartilage, and bone under chemically defined culture conditions. After in vivo transplantation of these cells into immunocompromised mice, they showed dense engraftment in various tissues. The relative ease of recovery and the expression profiles of various markers justify further exploration of IDPSC for clinical therapy.
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Citations
Cites
In vivo proliferation and cell cycle kinetics of long-term self-renewing hematopoietic stem cells
Cheshier, S. H., Morrison, S. J., Liao, X., & Weissman, I. L. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.6.3120 · Cited by 858
Cited by
Tatullo, M., Marrelli, M., Shakesheff, K. M., & White, L. J. (2015) · Journal of Tissue Engineering and Regenerative Medicine · doi:10.1002/term.1899 · Cited by 353
iPS Cells Reprogrammed From Human Mesenchymal-Like Stem/Progenitor Cells of Dental Tissue Origin
Yan, X., Qin, H., Qu, C., Tuan, R. S., Shi, S., & Huang, G. T.-J. (2010) · Stem Cells and Development · doi:10.1089/scd.2009.0314 · Cited by 344
Compromised dental cells viability following teeth-whitening exposure
Redha, O., Mazinanian, M., Nguyen, S., Son, D. O., Lodyga, M., Hinz, B., Odlyha, M., McDonald, A., & Bozec, L. (2021) · Scientific Reports · doi:10.1038/s41598-021-94745-w · Cited by 9
Metadata
- Authors
- Kerkis, I., Kerkis, A., Dozortsev, D., Stukart-Parsons, G. C., Gomes Massironi, S. M., Pereira, L. V., Caplan, A. I., & Cerruti, H. F.
- Venue
- Cells Tissues Organs
- Publisher
- S. Karger AG
- Published
- 2006
- Volume
- 184
- Issue
- 3-4
- Pages
- 105-116
- ISSN
- 1422-6405 (ISSN-L)
- 1422-6421
- OpenAlex
- W2036550391
- Cited by
- 509
- References
- 1
- FWCI
- 5.68
- Type
- journal article
- Language
- en
- Open access
- closed
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- The paper
- Kerkis, I., Kerkis, A., Dozortsev, D., Stukart-Parsons, G. C., Gomes Massironi, S. M., Pereira, L. V., Caplan, A. I., & Cerruti, H. F. (2006). Isolation and Characterization of a Population of Immature Dental Pulp Stem Cells Expressing OCT-4 and Other Embryonic Stem Cell Markers. Cells Tissues Organs. https://doi.org/10.1159/000099617
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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