The Assessment of Changes in Cognitive Functioning: Reliable Change Indices for Neuropsychological Instruments in the Elderly – A Systematic Review
Abstract
Background/aims The determination of meaningful cognitive change over time is essential for the diagnosis of dementia in the elderly. Reliable change indices (RCIs) represent a suitable methodology to assess clinically significant cognitive change. The purpose of this paper is to provide a systematic review of RCI scores in elderly persons for neuropsychological tests currently available. Methods A comprehensive literature search was conducted. Longitudinal studies dealing with the assessment of RCIs for cognitive instruments and cognitively healthy older participants were reviewed. Quality of studies was determined using a standardized system of evaluating methodical quality. Results A total of 11 studies met the inclusion criteria; half of the studies rated highly for methodical quality. RCI scores were summarized for a number of neuropsychological instruments. Conclusion RCIs have important implications regarding the interpretation of change in test scores in older adults. Further assessment and standardization is needed for many neuropsychological instruments.
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A 90% confidence interval for reliable change was employed to identify significant cognitive change beyond measurement error and practice effects, consistent with prevailing RCI literature.
“To identify if a patient's cognitive score has significantly changed beyond measurement error and practice effects, a 90% confidence interval for reliable change was employed, consistent with prevailing RCI literature.”
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References 43 · Cited by 65
- Authors
- Stein, J., Luppa, M., Brähler, E., König, H.-H., & Riedel-Heller, S. G.
- Affiliations
- Leipzig University (DE)
- Venue
- Dementia and Geriatric Cognitive Disorders
- Publisher
- S. Karger AG
- Published
- 2010
- Volume
- 29
- Issue
- 3
- Pages
- 275-286
- ISSN
- 1420-8008 (ISSN-L)
- 1421-9824
- OpenAlex
- W2088576310
- Cited by
- 65
- References
- 43
- Citations by year
- 2026: 3 · 2025: 4 · 2024: 4 · 2023: 2 · 2022: 4 · 2021: 3 · 2020: 6 · 2019: 8 · 2018: 3 · 2017: 4 · 2016: 1 · 2015: 5 · 2014: 4 · 2013: 2 · 2012: 6
- FWCI
- 0.63
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Dementia and Geriatric Cognitive Disorders (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
- Social Sciences › Psychology › Applied Psychology › Psychological Testing and Assessment
- Social Sciences › Psychology › Clinical Psychology › Historical and Modern Theater Studies
- Keywords
- reliable change index, cognitive change, neuropsychological assessment, older adults, dementia diagnosis, longitudinal cognitive assessment, test score interpretation, methodological quality
- MeSH terms
- Aged, Clinical Trials as Topic, Cognition, Cognition Disorders, Humans, Neuropsychological Tests, Mental Recall, Research, Verbal Learning, Geriatric Assessment, Randomized Controlled Trials as Topic, Disease Progression
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