Quality of Life in Medically Ill Persons with Comorbid Mental Disorders: A Systematic Review and Meta-Analysis
Abstract
Background This systematic review aims to investigate the association between comorbid mental disorders and quality of life (QoL) in patients with chronic medical diseases. Methods Studies investigating adults with diabetes mellitus, coronary artery disease, asthma, chronic back pain and colorectal cancer were included. Two reviewers independently extracted data and assessed methodological criteria. Effect sizes for QoL scores were analyzed in random-effects meta-analyses. Subgroup and sensitivity analyses were conducted. Results The database search identified 7,291 references and 65 primary studies were included. Medically ill persons with comorbid mental disorders showed a significantly decreased overall (d = -1.10; 95% CI = -1.34 to -0.86), physical (d = -0.64; 95% CI = -0.74 to -0.53) and psychosocial (d = -1.18; 95% CI = -1.42 to -0.95) QoL compared to persons without mental disorders. Subgroup analyses did not reveal significant differences between the examined medical diseases or mental disorders. Conclusion The review provides evidence of a substantially reduced psychosocial and physical QoL in medically ill patients with comorbid mental disorders. This patient-reported outcome highlights the importance of recognizing and treating comorbid mental disorders in the medically ill.
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In medical rehabilitation, 38% of patients have psychological distress.
“In der medizinischen Rehabilitation weisen 38 % der Patienten eine psychische Belastung und jeder fünfte Patient eine psychische Störung auf [ 7 ] .”
From Inanspruchnahmebereitschaft und Inanspruchnahmeverhalten von Behandlungen aufgrund psychischer Belastungen bei Patienten der somatischen Rehabilitation (2012) · cites this paper as [7]
The prevalence of psychological distress at t0 (34.4%) is comparable to the prevalence of psychological distress (38%) among patients in medical rehabilitation [7].
“Dies ist vergleichbar mit der Prävalenz psychischer Belastungen (38 %) bei Patienten der medizinischen Rehabilitation [ 7 ] .”
From Inanspruchnahmebereitschaft und Inanspruchnahmeverhalten von Behandlungen aufgrund psychischer Belastungen bei Patienten der somatischen Rehabilitation (2012) · cites this paper as [7]
Every fifth patient in medical rehabilitation has a mental disorder.
“In der medizinischen Rehabilitation weisen 38 % der Patienten eine psychische Belastung und jeder fünfte Patient eine psychische Störung auf [ 7 ] .”
From Inanspruchnahmebereitschaft und Inanspruchnahmeverhalten von Behandlungen aufgrund psychischer Belastungen bei Patienten der somatischen Rehabilitation (2012) · cites this paper as [7]
Es scheint zu keiner bedeutsamen Verzerrung gekommen zu sein, da beide Verfahren gute Gütekriterien aufweisen, die empfohlenen Cut-off-Werte verwendet wurden und die gezeigte Prävalenzrate psychischer Belastungen vergleichbar mit der in einer repräsentativen epidemiologischen Studie ist.
“Vor dem Hintergrund, dass beide Verfahren gute Gütekriterien aufweisen [ 28 , 29 ] , die empfohlenen Cut-off -Werte verwendet wurden [ 26 -28 ] und die gezeigte Prävalenzrate psychischer Belastungen vergleichbar mit der in einer repräsentativen epidemiologischen Studie [ 7 ] ist, scheint es zu keiner bedeutsamen Verzerrung gekommen zu sein.”
From Inanspruchnahmebereitschaft und Inanspruchnahmeverhalten von Behandlungen aufgrund psychischer Belastungen bei Patienten der somatischen Rehabilitation (2012) · cites this paper as [7]
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References 115 · Cited by 195
- Authors
- Baumeister, H., Hutter, N., Bengel, J., & Härter, M.
- Affiliations
- University of Freiburg (DE)
- University Medical Center Hamburg-Eppendorf (DE)
- Venue
- Psychotherapy and Psychosomatics
- Publisher
- S. Karger AG
- Published
- 2011
- Volume
- 80
- Issue
- 5
- Pages
- 275-286
- ISSN
- 0033-3190 (ISSN-L)
- 1423-0348
- OpenAlex
- W2043538665
- Cited by
- 195
- References
- 115
- Citations by year
- 2026: 7 · 2025: 14 · 2024: 10 · 2023: 21 · 2022: 20 · 2021: 10 · 2020: 13 · 2019: 4 · 2018: 12 · 2017: 12 · 2016: 12 · 2015: 12 · 2014: 12 · 2013: 21 · 2012: 11
- FWCI
- 1.80
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Psychotherapy and Psychosomatics (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Epidemiology › Chronic Disease Management Strategies
- Social Sciences › Psychology › Social Psychology › Mental Health Treatment and Access
- Social Sciences › Economics, Econometrics and Finance › Economics and Econometrics › Health Systems, Economic Evaluations, Quality of Life
- Keywords
- quality of life, comorbid mental disorders, chronic disease, diabetes mellitus, coronary artery disease, asthma, chronic back pain, colorectal cancer, psychosocial quality of life, physical quality of life, patient-reported outcomes
- MeSH terms
- Mental Disorders, Chronic Disease, Humans, Quality of Life, Comorbidity
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