The DOI matches its Crossref record.
Apathy Is Associated with Activities of Daily Living Ability in Parkinson's Disease
Abstract
Background Neuropsychiatric symptoms and impairment in performing activities of daily living (ADL) in patients with Parkinson's disease (PD) are strong predictors of the overall caregiver burden and they increase the risk for nursing home admission of the patients. The purpose of the present study was to assess the association of neuropsychiatric symptoms and ADL functions in PD. Methods A total of 73 community-dwelling PD patients were studied. The mean age of the patient group was 65 years and the mean disease duration was 9 years. The Neuropsychiatric Inventory was used to measure neuropsychiatric symptoms, and ADL abilities were measured by the Alzheimer's Disease Cooperative Study-Activities of Daily Living Inventory. Results The prevalence of neuropsychiatric symptoms in patients with PD was 73%. The most common symptoms were depression, anxiety, irritability, apathy and agitation. ADL ability correlated significantly with apathy (p Conclusion Apathy was significantly associated with ADL in PD. The result indicates that more attention should be paid to identifying apathy and targeting therapeutic interventions.
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“which has been found to interfere with PD motor disability treatment, exacerbating disability, and lowering quality of life and ability to carry out activities of daily living (ADL)”
From Remote delivery of psychological interventions for Parkinson's disease. (2018) · cites this paper as Laatu et al., 2013
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Research works printed but not linked: 25
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Cited by
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The clinical spectrum of anxiety in Parkinson's disease
Dissanayaka, N. N. N. W., White, E., O'Sullivan, J. D., Marsh, R., Pachana, N. A., & Byrne, G. J. (2014) · Movement Disorders · doi:10.1002/mds.25937 · Cited by 124
Remote delivery of psychological interventions for Parkinson's disease.
Swalwell, C., Pachana, N. A., & Dissanayaka, N. N. (2018) · International Psychogeriatrics · doi:10.1017/s1041610218000340 · Cited by 87
“…not necessarily associated with depression, which has been found to interfere with PD motor disability treatment, exacerbating disability, and lowering quality of life and ability to carry out activities of daily living (ADL) (Weintraub et al., 2004; Benito-Leon et al., 2012; Laatu et al., 2013).”
Background
Metadata
- Authors
- Laatu, S., Karrasch, M., Martikainen, K., & Marttila, R.
- Affiliations
- Turku University Hospital (FI)
- Åbo Akademi University (FI)
- Finnish Parkinson Foundation (FI)
- University of Turku (FI)
- ORCID
- Karrasch, M.
- Venue
- Dementia and Geriatric Cognitive Disorders
- Publisher
- S. Karger AG
- Published
- 2013
- Volume
- 35
- Issue
- 5-6
- Pages
- 249-255
- ISSN
- 1420-8008 (ISSN-L)
- 1421-9824
- OpenAlex
- W1995922883
- Cited by
- 37
- References
- 0
- Citations by year
- 2026: 2 · 2025: 1 · 2024: 3 · 2023: 4 · 2022: 3 · 2021: 1 · 2020: 3 · 2019: 1 · 2018: 3 · 2017: 5 · 2016: 2 · 2015: 4 · 2014: 4
- FWCI
- 2.12
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Dementia and Geriatric Cognitive Disorders (publishedVersion)
- PubMed (publishedVersion)
- Åbo Akademi University Research Portal (submittedVersion)
- Topics
- Health Sciences › Medicine › Clinical Neurology › Parkinson's Disease Mechanisms and Treatments
- Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
- Health Sciences › Medicine › Clinical Neurology › Deep Brain Stimulation and Movement Disorders
- Keywords
- Parkinson's disease, apathy, activities of daily living, neuropsychiatric symptoms, depression, anxiety, irritability, agitation, community-dwelling patients, caregiver burden, nursing home admission
- MeSH terms
- Activities of Daily Living, Adult, Aged, Aged, 80 and over, Antiparkinson Agents, Female, Humans, Male, Middle Aged, Neuropsychological Tests, Parkinson Disease, Psychiatric Status Rating Scales, Psychomotor Agitation, Regression Analysis, Apathy
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