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Cited by 377

The DOI matches its Crossref record; 41 of the 41 references it cites were found in a registry or an index.

Plasma Levels of Soluble Receptor for Advanced Glycation End Products and Coronary Artery Disease in Nondiabetic Men

Open access
Falcone, Colomba, Emanuele, Enzo, D’Angelo, Angela, Buzzi, Maria P., Belvito, Chiara, Cuccia, Mariaclara, Geroldi, Diego·2005·Arteriosclerosis, Thrombosis, and Vascular Biology

Abstract

Objective— The receptor for advanced glycation end products (RAGE) is a cell surface receptor whose signaling pathway has been implicated in atherogenesis. RAGE has an endogenous secretory receptor form, called soluble RAGE (sRAGE), that could exert antiatherogenic effects by acting as a decoy. We sought to determine whether a decreased plasma level of sRAGE could be independently associated with the prevalence of coronary artery disease (CAD) in nondiabetic men. Methods and Results— Plasma levels of sRAGE were determined in 328 nondiabetic male patients with angiographically proved CAD and in 328 age-matched healthy controls. The concentration of sRAGE in plasma was significantly lower ( P <0.0001) in CAD cases [median (interquartile range): 966 (658–1372) pg/mL] than in control subjects [1335 (936–1954) pg/mL]. In logistic regression analysis, the multivariate-adjusted odds ratio for the presence of CAD was 6.719 (95% confidence interval, 3.773 to 11.964; P <0.0001) when the lowest quartile of the sRAGE level was compared with the highest quartile. Conclusions— Our findings indicate that low levels of sRAGE in plasma are independently associated with the presence of CAD in nondiabetic men and suggest that sRAGE is one of the clinically important molecules associated with atherosclerosis.

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Crossref · 10.1161/01.atv.0000160342.20342.00

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Metadata

Authors
Falcone, C., Emanuele, E., D’Angelo, A., Buzzi, M. P., Belvito, C., Cuccia, M., & Geroldi, D.
Venue
Arteriosclerosis, Thrombosis, and Vascular Biology
Published
2005-05
Volume
25
Issue
5
Pages
1032-1037
ISSN
  • 1079-5642 (ISSN-L)
  • 1524-4636
OpenAlex
W1985236743
Cited by
377
References
41
FWCI
17.27
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Plasma Levels of Soluble Receptor for Advanced Glycation End Products and Coronary Artery Disease in Nondiabetic Men. https://app.cochat.ai/papers/10.1161/01.atv.0000160342.20342.00
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Falcone, C., Emanuele, E., D’Angelo, A., Buzzi, M. P., Belvito, C., Cuccia, M., & Geroldi, D. (2005). Plasma Levels of Soluble Receptor for Advanced Glycation End Products and Coronary Artery Disease in Nondiabetic Men. Arteriosclerosis, Thrombosis, and Vascular Biology. https://doi.org/10.1161/01.atv.0000160342.20342.00

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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