The DOI matches its Crossref record; 10 of the 10 references it cites were found in a registry or an index.
Lipoprotein Heterogeneity and Apolipoprotein B Metabolism
Abstract
Abstract The apolipoprotein B containing lipoproteins VLDL, IDL, and LDL exhibit variation in their structure, function, and metabolism. These major lipoprotein classes can be fractionated into apparently discrete components by density gradient centrifugation or affinity chromatography. Examination of the behavior of subfractions in vivo reveals the presence of metabolic channels within the VLDL-LDL delipidation cascade so that the pedigree of a lipoprotein in part determines its metabolic fate. Evidence from VLDL and LDL apoB turnovers together with epidemiological data allows the construction of a quantitative model for the generation of small, dense LDL. This lipoprotein subspecies is one component of the dyslipidemic syndrome known as the atherogenic lipoprotein phenotype, a common disorder in those at risk for coronary heart disease. Understanding lipoprotein heterogeneity is an essential step in the further discovery of the pathogenesis of atherosclerosis and in the tailoring of pharmacologic treatment for subjects at risk.
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Cites
Atherogenic lipoprotein phenotype. A proposed genetic marker for coronary heart disease risk
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Walsh, B. W., Schiff, I., Rosner, B., Greenberg, L., Ravnikar, V., & Sacks, F. M. (1991) · New England Journal of Medicine · doi:10.1056/nejm199110243251702 · Cited by 1,152
Griffin, B. A., Freeman, D. J., Tait, G. W., Thomson, J., Caslake, M. J., Packard, C. J., & Shepherd, J. (1994) · Atherosclerosis · doi:10.1016/0021-9150(94)90129-5 · Cited by 525
Self-citationGinsberg, H. N., Le, N. A., Goldberg, I. J., Gibson, J. C., Rubinstein, A., Wang-Iverson, P., Norum, R., & Brown, W. V. (1986) · Journal of Clinical Investigation · doi:10.1172/jci112713 · Cited by 424
Chapman, M. J., Laplaud, P. M., Luc, G., Forgez, P., Bruckert, E., Goulinet, S., & Lagrange, D. (1988) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)38518-7 · Cited by 216
Bjorkegren, J., Packard, C. J., Hamsten, A., Bedford, D., Caslake, M., Foster, L., Shepherd, J., Stewart, P., & Karpe, F. (1996) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)37637-9 · Cited by 187
Self-citationMcNamara, J. R., Small, D. M., Li, Z., & Schaefer, E. J. (1996) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)37557-x · Cited by 147
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Self-citationCapell, W. H., Zambon, A., Austin, M. A., Brunzell, J. D., & Hokanson, J. E. (1996) · Arteriosclerosis, Thrombosis, and Vascular Biology · doi:10.1161/01.atv.16.8.1040 · Cited by 95
Presence of multiple subpopulations of lipoproteins of intermediate density in normal subjects
Musliner, T. A., Giotas, C., & Krauss, R. M. (1986) · Arteriosclerosis: An Official Journal of the American Heart Association, Inc. · doi:10.1161/01.atv.6.1.79 · Cited by 87
Cited by
Borén, J., Chapman, M. J., Krauss, R. M., Packard, C. J., Bentzon, J. F., Binder, C. J., Daemen, M. J., Demer, L. L., Hegele, R. A., Nicholls, S. J., et al. (2020) · European Heart Journal · doi:10.1093/eurheartj/ehz962 · Cited by 1,601
Self-citationMetabolic origins and clinical significance of LDL heterogeneity
Berneis, K. K., & Krauss, R. M. (2002) · Journal of Lipid Research · doi:10.1194/jlr.r200004-jlr200 · Cited by 896
Diabetic dyslipidaemia: from basic research to clinical practice*
Taskinen, M.-R. (2003) · Diabetologia · doi:10.1007/s00125-003-1111-y · Cited by 888
Effect of sibutramine on weight maintenance after weight loss: a randomised trial
James, W. P. T., Astrup, A., Finer, N., Hilsted, J., Kopelman, P., Rössner, S., Saris, W. H. M., & Gaal, L. F. V. (2000) · The Lancet · doi:10.1016/s0140-6736(00)03491-7 · Cited by 817
Caligiuri, G., Rudling, M., Ollivier, V., Jacob, M.-P., Michel, J.-B., Hansson, G. K., & Nicoletti, A. (2003) · Molecular Medicine · doi:10.1007/bf03402102 · Cited by 332
Metadata
- Authors
- Packard, C. J., & Shepherd, J.
- Venue
- Arteriosclerosis, Thrombosis, and Vascular Biology
- Published
- 1997-12
- Volume
- 17
- Issue
- 12
- Pages
- 3542-3556
- ISSN
- 1079-5642 (ISSN-L)
- 1524-4636
- OpenAlex
- W2117950105
- Cited by
- 402
- References
- 10
- FWCI
- 16.70
- Type
- journal article
- Language
- en
- Open access
- closed
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- Packard, C. J., & Shepherd, J. (1997). Lipoprotein Heterogeneity and Apolipoprotein B Metabolism. Arteriosclerosis, Thrombosis, and Vascular Biology. https://doi.org/10.1161/01.atv.17.12.3542
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
