The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.
Value of Programmed Ventricular Stimulation After Tetralogy of Fallot Repair: A Multicenter Study
Abstract
Background— Studies have consistently shown that ventricular tachycardia (VT) and sudden cardiac death (SCD) complicate the long-term outcome after tetralogy of Fallot repair, yet the diagnostic and predictive value of electrophysiological testing in this population is uncertain. Methods and Results— A multicenter cohort of 252 patients with repaired tetralogy of Fallot undergoing programmed ventricular stimulation was followed up for 18.5±9.6 and 6.5±4.5 years after corrective surgery and electrophysiological testing, respectively. Clinical VT and/or SCD occurred in 24.6%. Sustained monomorphic VT and polymorphic VT were induced in 30.2% and 4.4%. Including polymorphic VT in the definition of inducibility improved sensitivity (66.1±6.0% versus 77.4±5.3%, P =0.0082) with a marginal reduction in specificity (81.6±2.8% versus 79.5±2.9%, P =0.0455). Positive and negative predictive values were 55.2±5.3% and 91.5±2.2%. Independent risk factors for inducibility were age at study ≥18 years (OR, 3.3), palpitations (OR, 2.8), prior palliative surgery (OR, 3.1), modified Lown criteria ≥2 (OR, 5.6), and cardiothoracic ratio ≥0.6 (OR, 3.3). Event-free survival rates in noninducible and inducible patients at 1, 5, 10, and 15 years were 97.9%, 92.8%, 89.3%, and 89.3% versus 79.4%, 62.6%, 58.7%, and 50.3%, respectively ( P <0.0001). Both inducible monomorphic VT [relative risk (RR), 5.0; P =0.0002] and polymorphic VT (RR, 12.9; P <0.0001) predicted future clinical VT and SCD. In a multivariate analysis, inducible sustained VT was an independent risk factor for subsequent events (RR, 4.7; 95% CI, 1.2 to 18.5; P =0.0268). Conclusions— Programmed ventricular stimulation is of diagnostic and prognostic value in risk stratifying patients with repaired tetralogy of Fallot. In this patient population, inducible sustained polymorphic VT should not be disregarded as nonspecific.
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Moss, A. J., Hall, W. J., Cannom, D. S., Daubert, J. P., Higgins, S. L., Klein, H., Levine, J. H., Saksena, S., Waldo, A. L., Wilber, D., et al. (1996) · New England Journal of Medicine · doi:10.1056/nejm199612263352601 · Cited by 4,165
A Randomized Study of the Prevention of Sudden Death in Patients with Coronary Artery Disease
Buxton, A. E., Lee, K. L., Fisher, J. D., Josephson, M. E., Prystowsky, E. N., & Hafley, G. (1999) · New England Journal of Medicine · doi:10.1056/nejm199912163412503 · Cited by 2,489
Gatzoulis, M. A., Balaji, S., Webber, S. A., Siu, S. C., Hokanson, J. S., Poile, C., Rosenthal, M., Nakazawa, M., Moller, J. H., Gillette, P. C., et al. (2000) · The Lancet · doi:10.1016/s0140-6736(00)02714-8 · Cited by 1,779
Self-citationNollert, G., Fischlein, T., Bouterwek, S., Böhmer, C., Klinner, W., & Reichart, B. (1997) · Journal of the American College of Cardiology · doi:10.1016/s0735-1097(97)00318-5 · Cited by 761
Sustained ventricular tachycardia in adult patients late after repair of tetralogy of Fallot
Harrison, D. A., Harris, L., Siu, S. C., MacLoghlin, C. J., Connelly, M. S., Webb, G. D., Downar, E., McLaughlin, P. R., & Williams, W. G. (1997) · Journal of the American College of Cardiology · doi:10.1016/s0735-1097(97)00316-1 · Cited by 277
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Priori, S. G., Blomström-Lundqvist, C., Mazzanti, A., Blom, N., Borggrefe, M., Camm, J., Elliott, P. M., Fitzsimons, D., Hatala, R., Hindricks, G., et al. (2015) · European Heart Journal · doi:10.1093/eurheartj/ehv316 · Cited by 3,893
Zeppenfeld, K., Tfelt-Hansen, J., de Riva, M., Winkel, B. G., Behr, E. R., Blom, N. A., Charron, P., Corrado, D., Dagres, N., de Chillou, C., et al. (2022) · European Heart Journal · doi:10.1093/eurheartj/ehac262 · Cited by 3,140
ACC/AHA/HRS 2008 guidelines for device-based therapy of cardiac rhythm abnormalities
Epstein, A. E., DiMarco, J. P., Ellenbogen, K. A., Estes, N. A. M., Freedman, R. A., Gettes, L. S., Gillinov, A. M., Gregoratos, G., Hammill, S. C., Hayes, D. L., et al. (2008) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2008.02.032 · Cited by 2,546
ESC Guidelines for the management of grown-up congenital heart disease (new version 2010)
Endorsed by the Association for European Paediatric Cardiology (AEPC), Authors/Task Force Members, Baumgartner, H., Bonhoeffer, P., De Groot, N. M. S., de Haan, F., Deanfield, J. E., Galie, N., Gatzoulis, M. A., Gohlke-Baerwolf, C., et al. (2010) · European Heart Journal · doi:10.1093/eurheartj/ehq249 · Cited by 2,331
Self-citation2020 ESC Guidelines for the management of adult congenital heart disease
Baumgartner, H., De Backer, J., Babu-Narayan, S. V., Budts, W., Chessa, M., Diller, G.-P., lung, B., Kluin, J., Lang, I. M., Meijboom, F., et al. (2021) · European Heart Journal · doi:10.1093/eurheartj/ehaa554 · Cited by 2,311
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Metadata
- Authors
- Khairy, P., Landzberg, M. J., Gatzoulis, M. A., Lucron, H., Lambert, J., Marçon, F., Alexander, M. E., & Walsh, E. P.
- Venue
- Circulation
- Published
- 2004-04-27
- Volume
- 109
- Issue
- 16
- Pages
- 1994-2000
- ISSN
- 0009-7322 (ISSN-L)
- 1524-4539
- OpenAlex
- W2084235265
- Cited by
- 436
- References
- 5
- FWCI
- 9.00
- Type
- journal article
- Language
- en
- Open access
- closed
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- Khairy, P., Landzberg, M. J., Gatzoulis, M. A., Lucron, H., Lambert, J., Marçon, F., Alexander, M. E., & Walsh, E. P. (2004). Value of Programmed Ventricular Stimulation After Tetralogy of Fallot Repair: A Multicenter Study. Circulation. https://doi.org/10.1161/01.cir.0000126495.11040.bd
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