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Utility of Fast Cine Magnetic Resonance Imaging and Display for the Detection of Myocardial Ischemia in Patients Not Well Suited for Second Harmonic Stress Echocardiography
Abstract
Background —Some patients referred for pharmacological stress testing with transthoracic echocardiography (TTE) are unable to undergo testing owing to poor acoustic windows. Fast cine MRI can be used to assess left ventricular contraction, but its utility for detection of myocardial ischemia in patients poorly suited for echocardiography is unknown. Methods and Results —One hundred fifty-three patients (86 men and 67 women aged 30 to 88 years) with poor acoustic windows that prevented adequate second harmonic TTE imaging were consecutively referred for MRI to diagnose inducible myocardial ischemia during intravenous dobutamine and atropine. Diagnostic studies were completed in an average of 53 minutes. No patients experienced myocardial infarction, ventricular fibrillation, exacerbation of congestive heart failure, or death. In patients who underwent computer-assisted quantitative coronary angiography, the sensitivity and specificity for detecting a >50% luminal diameter narrowing were 83% and 83%, respectively. In the 103 patients with a negative MRI examination, the cardiovascular occurrence–free survival rate was 97%. Conclusions —Fast cine cardiac MRI provides a mechanism to assess left ventricular contraction and diagnose inducible myocardial ischemia in patients not well suited for stress echocardiography.
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Cited by
2013 ESC guidelines on the management of stable coronary artery disease
Task Force Members, Montalescot, G., Sechtem, U., Achenbach, S., Andreotti, F., Arden, C., Budaj, A., Bugiardini, R., Crea, F., Cuisset, T., et al. (2013) · European Heart Journal · doi:10.1093/eurheartj/eht296 · Cited by 4,510
Fihn, S. D., Gardin, J. M., Abrams, J., Berra, K., Blankenship, J. C., Dallas, A. P., Douglas, P. S., Foody, J. M., Gerber, T. C., Hinderliter, A. L., et al. (2012) · Circulation · doi:10.1161/cir.0b013e318277d6a0 · Cited by 845
Clinical indications for cardiovascular magnetic resonance (CMR): Consensus Panel report?
PENNELL, D. (2004) · European Heart Journal · doi:10.1016/j.ehj.2004.06.040 · Cited by 747
Fleisher, L. A., Beckman, J. A., Brown, K. A., Calkins, H., Chaikof, E. L., Fleischmann, K. E., Freeman, W. K., Froehlich, J. B., Kasper, E. K., Kersten, J. R., et al. (2007) · Circulation · doi:10.1161/circulationaha.107.185699 · Cited by 587
Metadata
- Authors
- Hundley, W. G., Hamilton, C. A., Thomas, M. S., Herrington, D. M., Salido, T. B., Kitzman, D. W., Little, W. C., & Link, K. M.
- Venue
- Circulation
- Published
- 1999-10-19
- Volume
- 100
- Issue
- 16
- Pages
- 1697-1702
- ISSN
- 0009-7322 (ISSN-L)
- 1524-4539
- OpenAlex
- W2005682987
- Cited by
- 332
- References
- 0
- FWCI
- 11.24
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Utility of Fast Cine Magnetic Resonance Imaging and Display for the Detection of Myocardial Ischemia in Patients Not Well Suited for Second Harmonic Stress Echocardiography. https://app.cochat.ai/papers/10.1161/01.cir.100.16.1697
- The paper
- Hundley, W. G., Hamilton, C. A., Thomas, M. S., Herrington, D. M., Salido, T. B., Kitzman, D. W., Little, W. C., & Link, K. M. (1999). Utility of Fast Cine Magnetic Resonance Imaging and Display for the Detection of Myocardial Ischemia in Patients Not Well Suited for Second Harmonic Stress Echocardiography. Circulation. https://doi.org/10.1161/01.cir.100.16.1697
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