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Cited by 135Atherosclerosis and Cardiovascular DiseasesCholesterol and Lipid MetabolismNitric Oxide and Endothelin Effects

The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.

The Arterial Medial Cell, Smooth Muscle, or Multifunctional Mesenchyme?

WISSLER, ROBERT W.·1967·Circulation
DOI 10.1161/01.cir.36.1.1
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Abstract

UNDERSTANDING of the pathogenesisof atherosclerosis in man is still incom- plete.This is largely due to the dearth of data regarding the artery wall and its metab- olism.In this editorial emphasis will be placed on two basic assumptions regarding the artery wall and atherogenesis.1.The medial cells of the artery are of prime importance in the pathogenesis of atherosclerosis.2. They represent a single cell type in the arterial media, a cell which is probably responsible for the production of collagen, elastin, smooth muscle fibers, and base- ment membrane (acid mucopolysaccharides), and furthermore, they are the chief cell in which one can identify serum lipoproteins in human and animal atherosclerosis.Many histology textbooks still state that two separate cell types exist in the arterial media, smooth muscle cells and fibroblasts.I have yet to find an electron microscopist who has seen

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Crossref · 10.1161/01.cir.36.1.1

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Metadata

Authors
WISSLER, R. W.
Affiliations
University of Chicago (US)
Corresponding author
WISSLER, ROBERT W.
Venue
Circulation
Publisher
Ovid Technologies (Wolters Kluwer Health)
Published
1967-07
Volume
36
Issue
1
Pages
1-4
ISSN
  • 0009-7322 (ISSN-L)
  • 1524-4539
DOI
10.1161/01.cir.36.1.1
OpenAlex
W1984578831
Cited by
135
References
4
Citations by year
2026: 1 · 2025: 2 · 2024: 4 · 2023: 1 · 2022: 2 · 2021: 4 · 2019: 3 · 2015: 1 · 2012: 3
FWCI
4.35
Type
journal article
Language
en
Open access
closed
Locations
  • Circulation (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Life Sciences › Immunology and Microbiology › Immunology › Atherosclerosis and Cardiovascular Diseases
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Biochemistry › Cholesterol and Lipid Metabolism
  • Health Sciences › Medicine › Physiology (medical) › Nitric Oxide and Endothelin Effects
Keywords
atherogenesis, vascular smooth muscle cells, fibroblasts, collagen synthesis, elastin, basement membrane, serum lipoproteins
MeSH terms
Arteries, Arteriosclerosis, Connective Tissue, Muscle, Smooth

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