Cited by 116Cardiac Arrhythmias and TreatmentsCardiac electrophysiology and arrhythmiasAtrial Fibrillation Management and Outcomes

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Effects of procainamide and quinidine sulfate in the Wolff-Parkinson-White syndrome

Sellers, T D, Campbell, R W, Bashore, T M, Gallagher, J J·1977·Circulation

DOI 10.1161/01.cir.55.1.15

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Abstract

Thirty-three patients with Wolff-Parkinson-White syndrome were studied electrophysiologically before and after administration of intravenous procainamide and oral quinidine sulfate. Procainamide prolonged the shortest R-R (SRR) interval between two consecutive pre-excited beats during atrial fibrillation 20-70 msec in 15 of 21 patients with no change observed in 6 of 21 patients. Quinidine sulfate prolonged the SRR 20-170 msec in all 16. In 14 of 18 patients where procainamide and quinidine were comparable, quinidine prolonged the SRR 30-100 msec more than procainamide.

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Background
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Authors: Sellers, T. D., Campbell, R. W., Bashore, T. M., & Gallagher, J. J.
ORCID: Bashore, T M
Gallagher, J J
Venue: Circulation
Publisher: Ovid Technologies (Wolters Kluwer Health)
Published: 1977-01
Volume: 55
Issue: 1
Pages: 15-22
ISSN: 0009-7322 (ISSN-L)
1524-4539
DOI: 10.1161/01.cir.55.1.15
OpenAlex: W2054794815
Cited by: 116
References: 23
Citations by year: 2026: 2 · 2025: 3 · 2023: 2 · 2021: 1 · 2020: 2 · 2019: 3 · 2018: 2 · 2016: 2 · 2015: 6 · 2014: 1
FWCI: 9.43
Type: journal article
Language: en
Open access: closed
Locations: Circulation (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Arrhythmias and Treatments
Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac electrophysiology and arrhythmias
Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Atrial Fibrillation Management and Outcomes
Keywords: procainamide, quinidine sulfate, Wolff-Parkinson-White syndrome, atrial fibrillation, RR interval, antiarrhythmic drugs, electrophysiology
MeSH terms: Atrial Fibrillation, Electrophysiology, Female, Humans, Male, Procainamide, Quinidine, Wolff-Parkinson-White Syndrome

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Effects of procainamide and quinidine sulfate in the Wolff-Parkinson-White syndrome

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