The DOI matches its Crossref record; 14 of the 14 references it cites were found in a registry or an index.
Immediate and sustained hemodynamic and clinical improvement in chronic heart failure by an oral angiotensin-converting enzyme inhibitor.
Open accessAbstract
The hemodynamic effects of an oral angiotensin-converting enzyme inhibitor, captopril, were evaluated in 10 symptomatic patients with chronic congestive heart failure. In all patients there was a significant increase in cardiac output (average 28%), stroke volume (49%), and stroke work index (26%), along with a decrease in pulmonary capillary wedge pressure (48%), indicating improved left ventricular function. Modest decreases in heart rate and arterial pressure were also observed. In seven patients maintained on captopril therapy, repeat hemodynamic studies at 2 months revealed sustained effects. These beneficial hemodynamic effects were accompanied by clinical improvement and improved exercise tolerance during maintenance therapy. These findings suggest that captopril may be a useful therapeutic adjunct for the long-term management of patients with chronic congestive heart failure.
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Cites
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Cited by
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Metadata
- Authors
- Ader, R., Chatterjee, K., Ports, T., Brundage, B., Hiramatsu, B., & Parmley, W.
- Venue
- Circulation
- Published
- 1980-05
- Volume
- 61
- Issue
- 5
- Pages
- 931-937
- ISSN
- 0009-7322 (ISSN-L)
- 1524-4539
- OpenAlex
- W2074588774
- Cited by
- 288
- References
- 14
- FWCI
- 30.69
- Type
- journal article
- Language
- en
- Open access
- bronze
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- CoChat. (2026). Citation check: Immediate and sustained hemodynamic and clinical improvement in chronic heart failure by an oral angiotensin-converting enzyme inhibitor. https://app.cochat.ai/papers/10.1161/01.cir.61.5.931
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- Ader, R., Chatterjee, K., Ports, T., Brundage, B., Hiramatsu, B., & Parmley, W. (1980). Immediate and sustained hemodynamic and clinical improvement in chronic heart failure by an oral angiotensin-converting enzyme inhibitor. Circulation. https://doi.org/10.1161/01.cir.61.5.931
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
