The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Platelet accumulation in experimental angioplasty: time course and relation to vascular injury.
Abstract
Since platelet accumulation may be an important determinant of restenosis after angioplasty, the time course of 51Cr-labeled platelet accumulation after experimental angioplasty was evaluated in a deendothelialized, hypercholesterolemic rabbit preparation of atherosclerosis. Marked platelet accumulation (39.5 +/- 8.7 X 10(6) platelets/1 cm vessel length) was observed at 30 min and remained active until 4 hr after angioplasty. Total accumulation over 24 hr was 56.4 +/- 4.7 X 10(6) platelets/1 cm length. Histologic dissection was directly related to the degree of platelet accumulation, with 64 +/- 15 X 10(6) platelets/1 cm in the group with marked dissection and 8.7 +/- 3.7 X 10(6) platelets/1 cm in the group with minimal dissection (p less than .05). Increasing angiographic dissection also resulted in a trend toward increased platelet accumulation, and angiographic change in luminal diameter showed a significant correlation with platelet accumulation. It is concluded that marked platelet accumulation occurs early after transluminal angioplasty and is related to the extent of dissection. Restenosis may result from a complex interaction of platelet accumulation, vascular damage, and blood flow.
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Cites
Effect of Dipyridamole and Aspirin on Late Vein-Graft Patency after Coronary Bypass Operations
Chesebro, J. H., Fuster, V., Elveback, L. R., Clements, I. P., Smith, H. C., Holmes, D. R., Bardsley, W. T., Pluth, J. R., Wallace, R. B., Puga, F. J., et al. (1984) · New England Journal of Medicine · doi:10.1056/nejm198401263100401 · Cited by 516
Cited by
Platelet GPIIb/IIIa antagonists: the first anti-integrin receptor therapeutics.
Coller, B. S. (1997) · Journal of Clinical Investigation · doi:10.1172/jci119307 · Cited by 263
Metadata
- Authors
- Wilentz, J. R., Sanborn, T. A., Haudenschild, C. C., Valeri, C. R., Ryan, T. J., & Faxon, D. P.
- Venue
- Circulation
- Published
- 1987-03
- Volume
- 75
- Issue
- 3
- Pages
- 636-642
- ISSN
- 0009-7322 (ISSN-L)
- 1524-4539
- OpenAlex
- W1995798630
- Cited by
- 294
- References
- 1
- FWCI
- 21.33
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Platelet accumulation in experimental angioplasty: time course and relation to vascular injury. https://app.cochat.ai/papers/10.1161/01.cir.75.3.636
- The paper
- Wilentz, J. R., Sanborn, T. A., Haudenschild, C. C., Valeri, C. R., Ryan, T. J., & Faxon, D. P. (1987). Platelet accumulation in experimental angioplasty: time course and relation to vascular injury. Circulation. https://doi.org/10.1161/01.cir.75.3.636
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
