The DOI matches its Crossref record; 23 of the 23 references it cites were found in a registry or an index.
Determinants of sensitivity and specificity of electrocardiographic criteria for left ventricular hypertrophy.
Open accessAbstract
Numerous electrocardiographic criteria, which are largely dependent on fixed voltage thresholds, have been proposed for the diagnosis of left ventricular hypertrophy (LVH). Electrocardiographic criteria for LVH were examined in 4,684 subjects of the Framingham Heart Study who underwent echocardiographic study for LVH. Echocardiographic LVH was detected in 290 men (14.2%) and 465 women (17.6%). Electrocardiographic features of LVH were present in 2.9% of men (60/2,042) and 1.5% of women (39/2,642). The overall sensitivity of the electrocardiographic diagnosis of LVH was 6.9%, whereas specificity was 98.8%. Sensitivity of the electrocardiogram (ECG) for LVH was marginally lower in women than in men (5.6% vs. 9.0%, p = 0.075). Obesity was inversely associated with sensitivity (p less than 0.05, both sexes combined, sex-adjusted). Smoking was also inversely related to sensitivity (p = 0.001, both sexes combined, sex-adjusted). In contrast, sensitivity of the ECG increased with age (p less than 0.001, both sexes combined, sex-adjusted). These findings suggest that electrocardiographic detection of LVH can be improved by incorporating information about noncardiac factors that impact on electrocardiographic sensitivity for LVH, presumably by attenuating QRS voltage. New strategies that take into consideration sex, age, smoking status, and obesity might improve the sensitivity of the ECG without diminishing specificity.
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Cites
Sahn, D. J., DeMaria, A., Kisslo, J., & Weyman, A. (1978) · Circulation · doi:10.1161/01.cir.58.6.1072 · Cited by 7,430
Echocardiographic assessment of left ventricular hypertrophy: Comparison to necropsy findings
Devereux, R. B., Alonso, D. R., Lutas, E. M., Gottlieb, G. J., Campo, E., Sachs, I., & Reichek, N. (1986) · The American Journal of Cardiology · doi:10.1016/0002-9149(86)90771-x · Cited by 6,229
Echocardiographic determination of left ventricular mass in man. Anatomic validation of the method.
Devereux, R. B., & Reichek, N. (1977) · Circulation · doi:10.1161/01.cir.55.4.613 · Cited by 4,485
Epidemiological approaches to heart disease: the Framingham study
Dawber, T. R., Meadors, G. F., & Moore, F. E. (1951) · American Journal of Public Health and the Nations Health · doi:10.2105/ajph.41.3.279 · Cited by 2,148
Sokolow, M., & Lyon, T. P. (1949) · American Heart Journal · doi:10.1016/0002-8703(49)90562-1 · Cited by 1,980
CASALE, P. N., DEVEREUX, R. B., MILNER, M., ZULLO, G., HARSHFIELD, G. A., PICKERING, T. G., & LARAGH, J. H. (1986) · Annals of Internal Medicine · doi:10.7326/0003-4819-105-2-173 · Cited by 1,078
A point-score system for the ECG diagnosis of left ventricular hypertrophy
Romhilt, D. W., & Estes, E. H. (1968) · American Heart Journal · doi:10.1016/0002-8703(68)90035-5 · Cited by 856
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Self-citationEchocardiographic criteria for left ventricular hypertrophy: The Framingham heart study
Levy, D., Savage, D. D., Garrison, R. J., Anderson, K. M., Kannel, W. B., & Castelli, W. P. (1987) · The American Journal of Cardiology · doi:10.1016/0002-9149(87)91133-7 · Cited by 799
Self-citationLevy, D., Garrison, R. J., Savage, D. D., Kannel, W. B., & Castelli, W. P. (1989) · Annals of Internal Medicine · doi:10.7326/0003-4819-110-2-101 · Cited by 702
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Cited by
Levy, D., Garrison, R. J., Savage, D. D., Kannel, W. B., & Castelli, W. P. (1990) · New England Journal of Medicine · doi:10.1056/nejm199005313222203 · Cited by 5,699
Use and Misuse of the Receiver Operating Characteristic Curve in Risk Prediction
Cook, N. R. (2007) · Circulation · doi:10.1161/circulationaha.106.672402 · Cited by 2,112
Grading quality of evidence and strength of recommendations for diagnostic tests and strategies
Schünemann, H. J., Oxman, A. D., Brozek, J., Glasziou, P., Jaeschke, R., Vist, G. E., Williams, J. W., Kunz, R., Craig, J., Montori, V. M., et al. (2008) · BMJ · doi:10.1136/bmj.39500.677199.ae · Cited by 1,782
de Simone, G., Daniels, S. R., Devereux, R. B., Meyer, R. A., Roman, M. J., de Divitiis, O., & Alderman, M. H. (1992) · Journal of the American College of Cardiology · doi:10.1016/0735-1097(92)90385-z · Cited by 1,734
Santhanakrishnan, R., Wang, N., Larson, M. G., Magnani, J. W., McManus, D. D., Lubitz, S. A., Ellinor, P. T., Cheng, S., Vasan, R. S., Lee, D. S., et al. (2016) · Circulation · doi:10.1161/circulationaha.115.018614 · Cited by 870
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Metadata
- Authors
- Levy, D., Labib, S. B., Anderson, K. M., Christiansen, J. C., Kannel, W. B., & Castelli, W. P.
- Venue
- Circulation
- Published
- 1990-03
- Volume
- 81
- Issue
- 3
- Pages
- 815-820
- ISSN
- 0009-7322 (ISSN-L)
- 1524-4539
- OpenAlex
- W2037510063
- Cited by
- 531
- References
- 23
- FWCI
- 9.91
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Levy, D., Labib, S. B., Anderson, K. M., Christiansen, J. C., Kannel, W. B., & Castelli, W. P. (1990). Determinants of sensitivity and specificity of electrocardiographic criteria for left ventricular hypertrophy. Circulation. https://doi.org/10.1161/01.cir.81.3.815
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