Structural remodeling of cardiac myocytes in patients with ischemic cardiomyopathy.

Gerdes, A M; Kellerman, S E; Moore, J A; Muffly, K E; Clark, L C; Reaves, P Y; Malec, K B; McKeown, P P; Schocken, D D

doi:10.1161/01.cir.86.2.426

Structural remodeling of cardiac myocytes in patients with ischemic cardiomyopathy.

BACKGROUND Chronic ischemic heart disease may lead to ventricular dilation and congestive heart failure (ischemic cardiomyopathy [ICM]). The changes in cardiac myocyte shape associated with this dilation, however, are not known. METHODS AND RESULTS Left ventricular myocyte dimensions were assesse…