The DOI matches its Crossref record; 7 of the 7 references it cites were found in a registry or an index.
Sympathetic Activity in Obese Subjects With and Without Obstructive Sleep Apnea
Abstract
Background —Obese humans are reported to have increased muscle sympathetic nerve activity (MSNA). Obstructive sleep apnea (OSA) may also be accompanied by increased MSNA. Because there is a high prevalence of OSA in obese humans, it is possible that high MSNA reported in obese subjects may in fact reflect the presence of OSA in these subjects. We tested the hypothesis that obesity, per se, in the absence of OSA, is not accompanied by increased MSNA. Methods and Results —We measured MSNA in 25 healthy normal-weight subjects and 30 healthy sedentary obese subjects. All subjects were screened by history and examination to exclude subjects with OSA or hypertension. OSA was further excluded by overnight polysomnographic studies. Despite careful screening, polysomnography revealed that 1 of 25 normal-weight subjects and 9 of 30 obese subjects had occult OSA ( P =0.015). MSNA was similar in normal-weight subjects (41±3 bursts per 100 heartbeats) and obese subjects without sleep apnea (42±3 bursts per 100 heartbeats, P =0.99). MSNA in the 9 obese subjects with occult OSA was 61±8 bursts per 100 heartbeats, which was higher than MSNA in normal-weight subjects without sleep apnea ( P =0.02) and higher than MSNA in obese subjects without sleep apnea ( P =0.02). Conclusions —Obesity alone, in the absence of OSA, is not accompanied by increased sympathetic activity to muscle blood vessels.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
The Occurrence of Sleep-Disordered Breathing among Middle-Aged Adults
Young, T., Palta, M., Dempsey, J., Skatrud, J., Weber, S., & Badr, S. (1993) · New England Journal of Medicine · doi:10.1056/nejm199304293281704 · Cited by 10,183
Sympathetic neural mechanisms in obstructive sleep apnea.
Somers, V. K., Dyken, M. E., Clary, M. P., & Abboud, F. M. (1995) · Journal of Clinical Investigation · doi:10.1172/jci118235 · Cited by 2,527
Self-citationReaven, G. M., Lithell, H., & Landsberg, L. (1996) · New England Journal of Medicine · doi:10.1056/nejm199602083340607 · Cited by 1,435
Strollo, P. J., & Rogers, R. M. (1996) · New England Journal of Medicine · doi:10.1056/nejm199601113340207 · Cited by 1,313
Regional Sympathetic Nervous Activity and Oxygen Consumption in Obese Normotensive Human Subjects
Vaz, M., Jennings, G., Turner, A., Cox, H., Lambert, G., & Esler, M. (1997) · Circulation · doi:10.1161/01.cir.96.10.3423 · Cited by 404
Body fat and sympathetic nerve activity in healthy subjects.
Scherrer, U., Randin, D., Tappy, L., Vollenweider, P., Jéquier, E., & Nicod, P. (1994) · Circulation · doi:10.1161/01.cir.89.6.2634 · Cited by 383
Vollenweider, P., Randin, D., Tappy, L., Jéquier, E., Nicod, P., & Scherrer, U. (1994) · Journal of Clinical Investigation · doi:10.1172/jci117242 · Cited by 285
Cited by
Epidemiology of Obstructive Sleep Apnea: A Population Health Perspective
Young, T., Peppard, P. E., & Gottlieb, D. J. (2002) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.2109080 · Cited by 4,244
Poirier, P., Giles, T. D., Bray, G. A., Hong, Y., Stern, J. S., Pi-Sunyer, F. X., & Eckel, R. H. (2006) · Circulation · doi:10.1161/circulationaha.106.171016 · Cited by 3,165
Sleep-disordered Breathing and Cardiovascular Disease
SHAHAR, E., WHITNEY, C. W., REDLINE, S., LEE, E. T., NEWMAN, A. B., JAVIER NIETO, F., O'CONNOR, G. T., BOLAND, L. L., SCHWARTZ, J. E., & SAMET, J. M. (2001) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.163.1.2001008 · Cited by 2,901
Goldberger, J. J., Cain, M. E., Hohnloser, S. H., Kadish, A. H., Knight, B. P., Lauer, M. S., Maron, B. J., Page, R. L., Passman, R. S., Siscovick, D., et al. (2008) · Circulation · doi:10.1161/circulationaha.107.189375 · Cited by 1,450
Association of Nocturnal Arrhythmias with Sleep-disordered Breathing
Mehra, R., Benjamin, E. J., Shahar, E., Gottlieb, D. J., Nawabit, R., Kirchner, H. L., Sahadevan, J., & Redline, S. (2006) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.200509-1442oc · Cited by 1,262
Metadata
- Authors
- Narkiewicz, K., van de Borne, P. J. H., Cooley, R. L., Dyken, M. E., & Somers, V. K.
- Venue
- Circulation
- Published
- 1998-08-25
- Volume
- 98
- Issue
- 8
- Pages
- 772-776
- ISSN
- 0009-7322 (ISSN-L)
- 1524-4539
- OpenAlex
- W1965644737
- Cited by
- 523
- References
- 7
- FWCI
- 7.43
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Sympathetic Activity in Obese Subjects With and Without Obstructive Sleep Apnea. https://app.cochat.ai/papers/10.1161/01.cir.98.8.772
- The paper
- Narkiewicz, K., van de Borne, P. J. H., Cooley, R. L., Dyken, M. E., & Somers, V. K. (1998). Sympathetic Activity in Obese Subjects With and Without Obstructive Sleep Apnea. Circulation. https://doi.org/10.1161/01.cir.98.8.772
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
