The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
T-Tubule Function in Mammalian Cardiac Myocytes
Abstract
The transverse tubules (t-tubules) of mammalian cardiac ventricular myocytes are invaginations of the surface membrane. Recent studies have suggested that the structure and function of the t-tubules are more complex than previously believed; in particular, many of the proteins involved in cellular Ca 2+ cycling appear to be concentrated at the t-tubule. Thus, the t-tubules are an important determinant of cardiac cell function, especially as the main site of excitation-contraction coupling, ensuring spatially and temporally synchronous Ca 2+ release throughout the cell. Changes in t-tubule structure and protein expression occur during development and in heart failure, so that changes in the t-tubules may contribute to the functional changes observed in these conditions. The purpose of this review is to provide an overview of recent studies of t-tubule structure and function in cardiac myocytes.
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Cites
Heart Failure After Myocardial Infarction: Altered Excitation-Contraction Coupling
Gómez, A. M., Guatimosim, S., Dilly, K. W., Vassort, G., & Lederer, W. J. (2001) · Circulation · doi:10.1161/hc3201.092285 · Cited by 205
Cited by
Advanced maturation of human cardiac tissue grown from pluripotent stem cells
Ronaldson-Bouchard, K., Ma, S. P., Yeager, K., Chen, T., Song, L., Sirabella, D., Morikawa, K., Teles, D., Yazawa, M., & Vunjak-Novakovic, G. (2018) · Nature · doi:10.1038/s41586-018-0016-3 · Cited by 1,272
Models of cardiac tissue electrophysiology: Progress, challenges and open questions
Clayton, R. H., Bernus, O., Cherry, E. M., Dierckx, H., Fenton, F. H., Mirabella, L., Panfilov, A. V., Sachse, F. B., Seemann, G., & Zhang, H. (2011) · Progress in Biophysics and Molecular Biology · doi:10.1016/j.pbiomolbio.2010.05.008 · Cited by 585
ter Keurs, H. E. D. J., & Boyden, P. A. (2007) · Physiological Reviews · doi:10.1152/physrev.00011.2006 · Cited by 356
Calcium Signaling in Cardiac Myocytes
Fearnley, C. J., Roderick, H. L., & Bootman, M. D. (2011) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a004242 · Cited by 339
Lieu, D. K., Liu, J., Siu, C.-W., McNerney, G. P., Tse, H.-F., Abu-Khalil, A., Huser, T., & Li, R. A. (2009) · Stem Cells and Development · doi:10.1089/scd.2009.0052 · Cited by 160
Metadata
- Authors
- Brette, F., & Orchard, C.
- Venue
- Circulation Research
- Published
- 2003-06-13
- Volume
- 92
- Issue
- 11
- Pages
- 1182-1192
- ISSN
- 0009-7330 (ISSN-L)
- 1524-4571
- OpenAlex
- W2170853736
- Cited by
- 387
- References
- 1
- FWCI
- 10.69
- Type
- journal article
- Language
- en
- Open access
- closed
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- Brette, F., & Orchard, C. (2003). T-Tubule Function in Mammalian Cardiac Myocytes. Circulation Research. https://doi.org/10.1161/01.res.0000074908.17214.fd
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
