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Cited by 353

The DOI matches its Crossref record; 11 of the 11 references it cites were found in a registry or an index.

Analysis of vasoactivity of local pH, PCO2 and bicarbonate on pial vessels.

Open access
Kontos, H A, Raper, A J, Patterson, J L·1977·Stroke
DOI 10.1161/01.str.8.3.358
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Abstract

The mechanism by which the local effect of CO2ON pial arterioles is exerted was examined in anesthetized cats equipped with a cranial window for the direct observation of the microcirculation of the parietal cortex. The dilation of pial arterioles in response to application of artificial cerebrospinal fluid with low pH was the same whether or not the PCO2 of the solution was maintained in the normal range or markedly increased. The constriction of pial arterioles in response to application of artificial cerebrospinal fluid with high pH was the same whether or not the PCO2 of the solution was maintained in the normal range or markedly decreased. Finally, pial arterioles did not change their caliber in response to application of cerebrospinal fluid with unchanged pH but markedly increased or decreased Pco, or bicarbonate ion concentration. These results show that the action of CO2 on cerebral vessels is exerted via changes in extracellular fluid pH and that molecular CO2 and bicarbonate ions do not have independent vasoactivity on these vessels.

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Metadata

Authors
Kontos, H. A., Raper, A. J., & Patterson, J. L.
Venue
Stroke
Publisher
Ovid Technologies (Wolters Kluwer Health)
Published
1977-05
Volume
8
Issue
3
Pages
358-360
ISSN
  • 0039-2499 (ISSN-L)
  • 1524-4628
DOI
10.1161/01.str.8.3.358
OpenAlex
W2068835466
Cited by
353
References
11
FWCI
2.95
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Analysis of vasoactivity of local pH, PCO2 and bicarbonate on pial vessels. https://app.cochat.ai/papers/10.1161/01.str.8.3.358
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Kontos, H. A., Raper, A. J., & Patterson, J. L. (1977). Analysis of vasoactivity of local pH, PCO2 and bicarbonate on pial vessels. Stroke. https://doi.org/10.1161/01.str.8.3.358

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.