Vascular Smooth Muscle Cell Plasticity and Autophagy in Dissecting Aortic Aneurysms

Objective—: Recent studies suggested the occurrence of phenotypic switching of vascular smooth muscle cells (VSMCs) during the development of aortic aneurysm (AA). However, lineage-tracing studies are still lacking, and the behavior of VSMCs during the formation of dissecting AA is poorly underst…